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Crohn's Disease clinical trials in Houston, TX

17 studies for Crohn's Disease are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

RecruitingPhase 3
  • Baylor College of Medicine Medical Center ( Site 5020), Houston
  • Michael E. DeBakey VA Medical Center ( Site 5086), Houston
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

Study of Advanced Therapies for the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease or Ulcerative Colitis

RecruitingPhase 2
  • Integrity Advanced Therapeutics /ID# 283871, Houston
  • Novel Research - Bellaire /ID# 280925, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Oct 2, 2026 · NCT07697456

A Study of Vedolizumab in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) in the Community Setting

RecruitingPhase 4
  • Kelsey Research Foundation, Houston
  • MedCare Pharma LLC, Houston
  • Spring Clinical Research, Houston
Ages 18 to 80 · All sexes · Updated Sep 30, 2026 · NCT06581328

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

RecruitingPhase 2
  • Houston Methodist Hospital /ID# 265533, Houston
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2/3
  • Victorium Clinical Research, Houston
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07196722

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Novel Research, LLC, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06233461

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 85 · All sexes · Updated Sep 22, 2026 · NCT06226883

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

RecruitingPhase 4
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

A Study to Assess the Long-Term Safety of Ustekinumab Versus Other Biologics in Patients With Crohn's Disease and Ulcerative Colitis

RecruitingObservational study
  • BAMC, Houston
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT04372108

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Recruiting
  • Baylor College of Medicine, Houston
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors

RecruitingObservational study
  • M D Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated May 20, 2026 · NCT04751396

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

RecruitingPhase 3
  • Texas Children's Hospital - Baylor - PIN, Houston
Ages 2 and older · All sexes · Updated May 7, 2026 · NCT05442567

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

RecruitingPhase 3
  • Texas Children's Hospital, Houston
Ages 2 to 17 · All sexes · Updated May 5, 2026 · NCT04779320

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2
  • Houston Methodist Hospital, Houston
  • Novel Research, LLC, Bellaire · 7 mi away
Ages 18 to 75 · All sexes · Updated Apr 27, 2026 · NCT06456593

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

RecruitingPhase 2
  • Mirador Therapeutics Selected Site, Houston
Ages 18 to 80 · All sexes · Updated Mar 12, 2026 · NCT07113522

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

RecruitingPhase 4
  • Houston Methodist Hospital, Houston
Ages 18 to 80 · All sexes · Updated Jan 15, 2026 · NCT06257706

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.