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Head and Neck Squamous Cell Carcinoma clinical trials in Atlanta, GA

24 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Atlanta (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer

RecruitingPhase 2
  • Emory University Hospital Midtown, Atlanta
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06980038

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

RecruitingPhase 3
  • Emory University Hospital Midtown, Atlanta
Ages 60 and older · All sexes · Updated Sep 25, 2026 · NCT04892173

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

RecruitingPhase 1
  • Emory University, Atlanta
Ages 18 to 74 · All sexes · Updated Sep 25, 2026 · NCT07219212

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Emory Proton Therapy Center, Atlanta
  • Emory University Hospital Midtown, Atlanta
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • Morehouse, Atlanta
  • Piedmont Healthcare, Atlanta
  • Winship Cancer Institute, Emory University, Atlanta
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

A Study to See if Giving Fianlimab and Cemiplimab Together is Better Than Cemiplimab Alone at Treating Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • Emory University School of Medicine, Atlanta
Ages 18 and older · All sexes · Updated Aug 21, 2026 · NCT06769698

Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer

RecruitingPhase 2/3
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04333537

Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)

RecruitingPhase 1/2
  • Winship Cancer Institute - Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT04198766

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation

Recruiting
  • Emory Midtown University Hospital/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06662058

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Winship Cancer Institute, Emory University, Atlanta
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of Dostarlimab vs Placebo After Chemoradiation in Adult Participants With Locally Advanced Unresected Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • GSK Investigational Site, Atlanta
Ages 18 and older · All sexes · Updated May 26, 2026 · NCT06256588

DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • USA10-0, Atlanta
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06953089

Surgeon-performed Ultrasound for Real-time Guidance In Oral Cancer Surgeries - A Multicenter Randomized Controlled Trial

Recruiting
  • Emory University Hospital, Atlanta
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT07203911

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • Emory University, Atlanta
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

A Study of DB-1310 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 111, Atlanta
Ages 18 and older · All sexes · Updated Apr 6, 2026 · NCT05785741

TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer

RecruitingPhase 1
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Mar 4, 2026 · NCT06868433

Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP Trial

RecruitingPhase 2
  • Emory University Hospital Midtown, Atlanta
  • Emory University Hospital/Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Feb 11, 2026 · NCT06636734

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 114, Atlanta
  • Research Site 139, Atlanta
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer

RecruitingEarly phase 1
  • Emory University Hospital Midtown, Atlanta
Ages 18 and older · All sexes · Updated Oct 22, 2025 · NCT06914999

A Beta-only IL-2 ImmunoTherapY Study

RecruitingPhase 1/2
  • Emory - Winship Cancer Institute, Atlanta
Ages 18 and older · All sexes · Updated Jul 9, 2025 · NCT05086692

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Atlanta

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.