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Major Depressive Disorder clinical trials in Atlanta, GA
24 studies for Major Depressive Disorder are looking for participants at sites in and around Atlanta (within about 30 miles). Open a study to see who can join and how to contact the study team.
Regulated Stimulation for Optimized Network Activity and Therapeutic Equilibrium
Recruiting
- Emory Healthcare, Atlanta
JAK Signaling in Depression
RecruitingPhase 2
- Emory University, Atlanta
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
RecruitingPhase 3
- Advanced Discovery Research, Atlanta
- Agile Clinical Research Trials, LLC, Atlanta
- iResearch Atlanta LLC, Decatur · 6 mi away
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
RecruitingPhase 3
- Peachford Hospital-Atlanta Behavioral Research, Atlanta
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
RecruitingPhase 3
- The Emory Clinic, Atlanta
- CenExeli Research LLC, Decatur · 6 mi away
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
RecruitingPhase 2
- Seaport Investigator Site, Atlanta
- Seaport Investigator Site, Decatur · 6 mi away
Leucine in Midlife Depression
RecruitingPhase 2
- Emory University Hospital, Atlanta
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
RecruitingPhase 3
- Delricht Research, Atlanta
- Emory University Brain Health Center, Atlanta
A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
RecruitingPhase 2
- Draig Clinical Site, Decatur · 6 mi away
Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)
Recruiting
- Emory University Hospital, Atlanta
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
RecruitingPhase 3
- Agile Clinical Research Trials, LLC, Atlanta
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
RecruitingPhase 2
- Draig Clinical Site, Atlanta
- Draig Clinical Site, Decatur · 6 mi away
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, Atlanta
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
RecruitingPhase 3
- CenExel - Atlanta Center for Medical Research, Atlanta
- CenExel - iResearch Atlanta, Decatur · 6 mi away
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
RecruitingPhase 3
- CenExel iResearch, LLC, Decatur · 6 mi away
A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
RecruitingPhase 3
- Advanced Discovery Research, Atlanta
- Synexus - Atlanta, Atlanta
A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive Disorder
RecruitingPhase 2
- Denali Health Atlanta, LLC, Stone Mountain · 13 mi away
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
RecruitingPhase 3
- Neurocrine Clinical Site, Atlanta
Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol
RecruitingPhase 3
- Clinical Research Site, Atlanta
A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive Disorder
RecruitingPhase 2
- Trialmed /ID# 277601, Atlanta
Glutamatergic Adaptation to Stress as a Mechanism for Anhedonia and Treatment Response With Ketamine
RecruitingEarly phase 1Healthy volunteers welcome
- Emory University, Atlanta
A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
RecruitingPhase 2
- CenExcel, Decatur · 6 mi away
Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)
RecruitingPhase 2
- Autobahn Site #112, Decatur · 6 mi away
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
RecruitingPhase 4
- Clinical Research Site, Atlanta
Major Depressive Disorder trials in other cities
- New York City, NY37 studies
- Boston, MA30 studies
- Philadelphia, PA22 studies
- Orlando, FL19 studies
- Tampa, FL17 studies
- Miami, FL17 studies
- Chicago, IL16 studies
- Houston, TX16 studies
- San Diego, CA16 studies
- Little Rock, AR14 studies
- Austin, TX13 studies
- Orange, CA13 studies
Other studies in Atlanta
- Cancer (all types)50 studies
- Non-Small Cell Lung Cancer46 studies
- Multiple Myeloma41 studies
- Breast Cancer41 studies
- Prostate Cancer32 studies
- Lung Cancer29 studies
- Colorectal Cancer29 studies
- Acute Myeloid Leukemia29 studies
- Ovarian Cancer28 studies
- Metastatic Cancer27 studies
- Obesity25 studies
- Heart Failure25 studies
From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.