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Lung Cancer clinical trials in New York City, NY

60 studies for Lung Cancer are looking for participants at sites in and around New York City (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study of ZW251 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07164313

A Study of Mental Health Care in People With Cancer

Recruiting
  • Memorial Sloan Kettering Cancer Center, New York
Ages 65 and older · All sexes · Updated Oct 5, 2026 · NCT06037954

Safety and Efficacy of OBX-115 in Advanced Solid Tumors

RecruitingPhase 1/2
  • Memorial Sloan Kettering (Melanoma/NSCLC), New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06060613

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

RecruitingPhase 3
  • Mount Sinai Chelsea, New York
  • Mount Sinai Hospital, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT04181060

Adding Certolizumab to Chemotherapy + Nivolumab in People Who Have Lung Cancer That Can Be Treated With Surgery

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT04991025

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering, New York
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Empathic Communication Skills (ECS) Training

RecruitingHealthy volunteers welcome
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 to 100 · All sexes · Updated Oct 1, 2026 · NCT05456841

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Memorial Sloan Kettering Hospital, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • NYU Langone's Perlmutter Cancer Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

Symbiotic-Lung-14: A Study to Learn About the Study Medicine Called PF08634404 in Combination With Chemotherapy in Adult Participants With Transformed Small Cell Lung Cancer

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center - David H. Koch Center for Cancer Care (74th Street)., New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07476287

A Registry for People With Lung Cancer

RecruitingObservational study
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06424327

Study of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)

RecruitingPhase 2/3
  • NYU Langone Health, New York
  • Weill Cornell Medical College, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07100080

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Columbia University, New York
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • NYU Langone Health Perlmutter Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Testing the Combination of an Anti-cancer Drug, Iadademstat, With Other Anti-cancer Drugs (Atezolizumab or Durvalumab) at Improving Outcomes for Small Cell Lung Cancer

RecruitingPhase 1/2
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT06287775

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • NYU Langone Medical Center - Perlmutter Cancer Center (NYU Cancer Institute), New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Columbia University Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06561685

A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer

RecruitingPhase 3
  • Laura and Isaac Perlmutter Cancer Center, New York
  • Manhattan Eye, Ear and Throat Hospital, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06119581

A Study of Sofe-M in Participants With Selected Advanced Solid Tumors

RecruitingPhase 1
  • New York University (NYU) Clinical Cancer Center, New York
  • David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06400472

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, New York
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • Perlmutter Cancer Center - NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Safety and Efficacy of BNT327, an Investigational Therapy in Combination With Chemotherapy for Patients With Untreated Small-cell Lung Cancer

RecruitingPhase 3
  • Cornell University - NewYork-Presbyterian/Weill Cornell Medical Center, New York
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT06712355

Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma

RecruitingPhase 1
  • New York Cancer & Blood Specialists, New York
Ages 18 and older · All sexes · Updated Aug 27, 2026 · NCT06582017

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • New York Proton Center, New York
  • Manhattan Eye Ear and Throat Hospital, New York
  • Memorial Sloan Kettering Cancer Center, New York
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial

RecruitingPhase 3
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
  • New York Proton Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06500481

A Study of Lung Cancer Risk

RecruitingObservational studyHealthy volunteers welcome
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 40 to 74 · All sexes · Updated Aug 14, 2026 · NCT07701733

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

RecruitingPhase 2
  • Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06518057

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, New York
  • Xencor Investigative Site, New York
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Study of a Side Effects and Resource Navigation Program for People With Cancer

Recruiting
  • City College of New York (Data Collection AND Specimen Analysis), New York
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT07646847

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • New York University Langone Health, New York
  • Icahn School of Medicine at Mount Sinai, New York
  • Columbia University Medical Center, New York
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • New York University Langone Medical Center, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • NYU Langone Medical Center, New York
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer

RecruitingPhase 1/2
  • Weill Medical College of Cornell University, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 to 70 · All sexes · Updated Jun 11, 2026 · NCT05361174

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, New York
  • Research Site, New York
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT05419076

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • NYU Langone, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Perlmutter Cancer Center at NYU Langone Health, New York
  • Memorial Sloan-Kettering Cancer Center, New York
  • Columbia University, New York
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT06922591

Brodalumab in the Treatment of Immune-Related Adverse Events

RecruitingPhase 1
  • Columbia University Irving Medical Center, New York
Ages 18 and older · All sexes · Updated May 13, 2026 · NCT06673329

Lung Cancer Biomarkers and Screening

RecruitingObservational studyHealthy volunteers welcome
  • NYU Cancer Institute at New York University Medical Center, New York
Ages 50 and older · All sexes · Updated May 8, 2026 · NCT00301119

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Memorial Sloan Kettering Cancer Center, New York
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors

RecruitingPhase 1/2
  • Laura & Isaac Perlmutter Cancer Center at NYU Langone, New York
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT07020221

Preoperative Radioimmunotherapy Versus Chemoimmunotherapy in NSCLC

RecruitingPhase 2
  • Weill Cornell Medicine, New York
Ages 18 and older · All sexes · Updated Apr 21, 2026 · NCT06623656

Safety and Tolerability of TNG456 Alone and in Combination With Abemaciclib in Patients With Solid Tumors With MTAP Loss

RecruitingPhase 1/2
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Apr 13, 2026 · NCT06810544

Confocal Laser Endomicroscopy VERification

Recruiting
  • Montefiore Medical Center, New York
Ages 18 and older · All sexes · Updated Apr 7, 2026 · NCT06079970

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • NYU Langone Health, New York
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Manhattan Eye Ear and Throat Hospital, New York
  • Lenox Hill Hospital, New York
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma

RecruitingPhase 1/2
  • Weill Cornell Medicine, Cornell University (site 126), New York
Ages 18 to 80 · All sexes · Updated Dec 11, 2025 · NCT03556228

Longitudinal Evaluation of Microbial and Host Signatures During Immunotherapy for Lung Cancer

RecruitingObservational study
  • NYU Langone Health, New York
Ages 18 to 100 · All sexes · Updated Dec 2, 2025 · NCT04063501

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, New York
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®

RecruitingPhase 2
  • NYU Langone Health, New York
Ages 18 and older · All sexes · Updated Apr 4, 2025 · NCT03290534

Genomic and Methylation Markers in SCLC and LCNEC for Chemo-Immunotherapy Resistance Prediction (STRATUS)

RecruitingObservational study
  • Icahn School of Medicine at Mount Sinai, New York
Ages 18 to 85 · All sexes · Updated Mar 19, 2025 · NCT06717243

Comprehensive Outcomes for After Cancer Health

RecruitingHealthy volunteers welcome
  • Memorial Sloan Kettering Cancer Center, New York
Ages 18 and older · All sexes · Updated Dec 11, 2024 · NCT05349227

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in New York City

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.