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Metastatic Cancer clinical trials in Sacramento, CA

16 studies for Metastatic Cancer are looking for participants at sites in and around Sacramento (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Mercy Cancer Center - Sacramento, Sacramento
  • Woodland Memorial Hospital, Woodland · 16 mi away
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

Testing the Safety and Tolerability of the Anti-cancer Drugs Trastuzumab Deruxtecan and Neratinib for Cancers With Changes in the HER2 Gene

RecruitingPhase 1
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05372614

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • University of California, Davis Comprehensive Cancer Center, Sacramento
  • University of California, Davis Medical Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1)

RecruitingPhase 1/2
  • UC Davis Comprehensive Cancer Center, Sacramento
Ages 12 and older · All sexes · Updated Sep 24, 2026 · NCT05118789

A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract

RecruitingPhase 3
  • University of California Davis (UC Davis) Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07218380

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • UC Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas

RecruitingPhase 1
  • The University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06389123

FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3

RecruitingPhase 1
  • University of California (UC) Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Aug 20, 2026 · NCT05614739

TR-002 for the Treatment of Advanced Unresectable Metastatic Solid Tumors Unresectable or Metastatic, Refractory Pancreatic Adenocarcinoma

RecruitingPhase 1
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT07189195

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Sutter Institute for Medical Research, Sacramento
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • University of California Davis, Sacramento
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

A Study of Neladalkib (NVL-655) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ALK Rearrangement or Activating ALK Mutation (ALKOVE-1)

RecruitingPhase 1/2
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 12 and older · All sexes · Updated May 27, 2026 · NCT05384626

A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1)

RecruitingPhase 1
  • University of California, Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Feb 25, 2026 · NCT06521554

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • University of California Davis Comprehensive Cancer Center, Sacramento
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Metastatic Cancer trials in other cities

Other studies in Sacramento

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.