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Non-Small Cell Lung Cancer clinical trials in Birmingham, AL

22 studies for Non-Small Cell Lung Cancer are looking for participants at sites in and around Birmingham (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Clinical Study of Calderasib (MK-1084) and Other Treatments for Participants With Non-Small Cell Lung Cancer (MK-1084-007/KANDLELIT-007)

RecruitingPhase 3
  • Central Alabama Research ( Site 0108), Birmingham
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07190248

Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)

RecruitingPhase 3
  • Alabama Oncology, Birmingham
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT06881784

A Study to Learn About the Study Medicine Called PF-08046054/SGN-PDL1V Versus Docetaxel in Adult Participants With Previously-Treated Programmed Cell Death Ligand 1 (PD-L1) Positive Non-Small-Cell Lung Cancer (NSCLC)

RecruitingPhase 3
  • Alabama Oncology, St Vincent's Birmingham, Birmingham
  • Alabama Oncology, Brookwood, Birmingham
  • Alabama Oncology, Princeton, Birmingham
  • and 5 more
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07144280

A Study to Investigate Ubamatamab With and Without Marlotamig (REGN7075) in Adult Participants With Advanced/Metastatic Non-Small Cell Lung Cancer (NSCLC)

RecruitingPhase 2
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07154290

Pan-tumor MRD Study

RecruitingObservational study
  • Alabama Oncology, Birmingham
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • Birmingham Hematology and Oncology Associates LLC d/b/a Alabama Oncology, Birmingham
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors

RecruitingPhase 1/2
  • UAB Medicine - UAB Hospital, Birmingham
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07488676

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

RecruitingPhase 1/2
  • The University of Alabama, Birmingham
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06303505

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

A Study of PRMT5 Inhibitor BAY 3713372 in Participants With MTAP-deleted Solid Tumors

RecruitingPhase 1/2
  • UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital, Birmingham
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06914128

Open-label Study of BBO-8520 in Adult Subjects With KRASG12C Non-small Cell Lung Cancer

RecruitingPhase 1
  • O'Neal Comprehensive Cancer Center at UAB, Birmingham
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06343402

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

RecruitingPhase 1
  • Uni of Alabama at Birmingham, Birmingham
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study of PF-08046054/SGN-PDL1V in Advanced Solid Tumors

RecruitingPhase 1
  • University of Alabama at Birmingham, Birmingham
  • University of Alabama at Birmingham, IDS Pharmacy, Birmingham
  • University of Alabama at Birmingham, Birmingham
  • and 1 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05208762

LUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLC

RecruitingPhase 3
  • Central Alabama Research, Birmingham
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT06216301

DISCERN: Dual Versus Single ICB in PDL-1 Negative NSCLC

RecruitingPhase 2
  • University of Alabama at Birmingham, Birmingham
Ages 18 to 89 · All sexes · Updated Jun 15, 2026 · NCT06364917

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

Safety and Preliminary Efficacy of Pumitamig (BNT327), an Investigational Therapy for Patients With Non-small Cell Lung Cancer in Combination With Chemotherapy as First-line or Second-line Treatment

RecruitingPhase 2
  • The University of Alabama at Birmingham Hospital, Birmingham
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT06841055

GEMINI-NSCLC: NSCLC Biomarker Study

RecruitingObservational study
  • Alabama Oncology, Birmingham
Ages 18 and older · All sexes · Updated Feb 5, 2026 · NCT05236114

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Birmingham
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Non-Small Cell Lung Cancer trials in other cities

Other studies in Birmingham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.