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COPD clinical trials in Birmingham, AL

18 studies for COPD are looking for participants at sites in and around Birmingham (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

RecruitingPhase 2
  • University of Alabama at Birmingham, Birmingham
Ages 40 to 75 · All sexes · Updated Sep 25, 2026 · NCT07759245

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

RecruitingPhase 4
  • University of Alabama at Birmingham - School of Medicine- Site Number : 8400003, Birmingham
Ages 40 to 85 · All sexes · Updated Sep 22, 2026 · NCT07053423

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

RecruitingPhase 3
  • University of Alabama at Birmingham- Site Number : 8400003, Birmingham
Ages 40 to 80 · All sexes · Updated Sep 15, 2026 · NCT07190222

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

RecruitingPhase 2
  • Research Site, Birmingham
Ages 40 and older · All sexes · Updated Sep 9, 2026 · NCT07082738

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

RecruitingPhase 2
  • University of Alabama, Birmingham
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07059091

A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease

RecruitingPhase 1
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06603246

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

RecruitingPhase 2/3
  • University of Alabama at Birmingham Lung Health Center, Birmingham
Ages 35 to 80 · All sexes · Updated Aug 31, 2026 · NCT07363694

Improving Patient-Centered Care for Underserved Older African American Patients With Cardiovascular Comorbidities

RecruitingObservational study
  • Cooper Green Mercy Hospital, Birmingham
Ages 50 to 99 · All sexes · Updated Aug 6, 2026 · NCT07748858

Multi-Center Clean Air Randomized Controlled Trial in COPD

RecruitingPhase 3
  • University of Alabama, Lung Health Center, Birmingham
Ages 40 and older · All sexes · Updated Jul 31, 2026 · NCT06376994

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

Recruiting
  • The University of Alabama at Birmingham, Birmingham
Ages 22 and older · All sexes · Updated Jun 23, 2026 · NCT07222410

SPIROMICS Study of Early COPD Progression (SOURCE)

RecruitingObservational studyHealthy volunteers welcome
  • University of Alabama at Birmingham, Birmingham
Ages 30 to 55 · All sexes · Updated Jun 3, 2026 · NCT05033990

Effect of Ensifentrine on Sputum Markers of Inflammation in COPD

RecruitingPhase 2
  • University of Alabama at Birmingham, Birmingham
Ages 40 to 80 · All sexes · Updated May 13, 2026 · NCT05270525

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

Recruiting
  • University of Alabama-Birmingham Hospital - UAB Lung Health Center, Birmingham
Ages 40 to 80 · All sexes · Updated Apr 28, 2026 · NCT07051707

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Recruiting
  • University of Alabama at Birmingham, Birmingham
Ages 40 to 84 · All sexes · Updated Apr 24, 2026 · NCT06891755

PiMZ Longitudinal Cohort (PiMZ Logic)

RecruitingObservational study
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06505603

Genetic Variation in IgG in Alpha 1 Antitrypsin Deficiency

RecruitingPhase 4
  • University of Alabama at Birmingham, Birmingham
Ages 19 and older · All sexes · Updated Nov 10, 2025 · NCT07135427

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Recruiting
  • UAB School of Medicine/Lung Health Center, Birmingham
Ages 30 and older · All sexes · Updated Feb 6, 2025 · NCT05204888

About COPD

COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. At first symptoms are mild, but they usually become more severe. Learn more.

More about COPD on MedlinePlus

COPD trials in other cities

Other studies in Birmingham

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.