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Amyloidosis clinical trials in Boston, MA

11 studies for Amyloidosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

RecruitingObservational study
  • Research Site, Boston
  • Research Site, Boston
  • Research Site, Boston
Ages 18 to 130 · All sexes · Updated Sep 23, 2026 · NCT06465810

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

RecruitingPhase 3
  • Clinical Trial Site, Boston
  • Clinical Trial Site, Boston
Ages 18 to 85 · All sexes · Updated Sep 16, 2026 · NCT07052903

TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy

RecruitingPhase 3
  • Clinical Trial Site, Boston
Ages 18 to 85 · All sexes · Updated Sep 15, 2026 · NCT07223203

DemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World Setting

RecruitingObservational study
  • Clinical Trial Site, Boston
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07358078

Prevalence and Prediction of ATTR in Ambulatory Patients With HFpEF

Recruiting
  • Massachusetts General Hospital, Boston
Ages 65 and older · All sexes · Updated Sep 1, 2026 · NCT05577819

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

RecruitingPhase 3
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
  • Boston University (BU) School of Medicine, Boston
Ages 18 to 75 · All sexes · Updated Aug 4, 2026 · NCT06563895

[64Cu]FBP8 PET for Early Detection of Intracardiac Thrombus in Amyloid Cardiomyopathy

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT07560306

A Phase 1b/2 Study of CAR T Cell Therapy Targeting CD19 and BCMA in Participants With Relapsed or Refractory AL Amyloidosis.

RecruitingPhase 1/2
  • Research Site, Boston
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT07081646

MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM)

RecruitingPhase 3
  • Brigham and Women's Hospital, Boston
  • Boston University School of Medicine, Boston
Ages 18 to 90 · All sexes · Updated Mar 27, 2026 · NCT06128629

Molecular Imaging of Primary Amyloid Cardiomyopathy

Recruiting
  • Brigham and Womens' Hospital, Boston
Ages 18 to 99 · All sexes · Updated Nov 14, 2025 · NCT02641145

About Amyloidosis

Amyloidosis is a rare condition that can affect different organs of the body. Find out about amyloidosis treatment and symptoms.

More about Amyloidosis on MedlinePlus

Amyloidosis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.