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Chronic Lymphocytic Leukemia clinical trials in Seattle, WA

20 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Swedish Medical Center-Ballard Campus, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • and 1 more
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies.

RecruitingPhase 1/2
  • Research Site, Seattle
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06542250

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

RecruitingPhase 3
  • Fred Hutchinson Cancer Center, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • FHCC at Northwest Hospital, Seattle
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT04269902

A Dose-Escalation and Expansion Study of Tacabrutideg (BGB-16673) in Participants With B-Cell Malignancies

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT05006716

A Study to Investigate Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Acalabrutinib in Adults With Previously Untreated Chronic Lymphocytic Leukemia

RecruitingPhase 3
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07277231

A Study to Investigate the Safety of Novel Dose Ramp-up Schedule(s) When Initiating Sonrotoclax in Participants Treated for Blood Cancers.

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06697184

A Study to Evaluate the Safety and Efficacy of Tacabrutideg (BGB-16673) Compared to Pirtobrutinib in Adults With Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

RecruitingPhase 3
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06973187

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

RecruitingPhase 2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07221500

Nemtabrutinib and Lisocabtagene Maraleucel for the Treatment of Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT07194980

A Phase 1 Study of UB-VV111 With and Without Rapamycin in Relapsed/Refractory CD19+ B-cell Malignancies

RecruitingPhase 1
  • Fred Hutch Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06528301

Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies

RecruitingPhase 2Healthy volunteers welcome
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
6 Months · All sexes · Updated May 29, 2026 · NCT04195633

Acalabrutinib in Combination With Venetoclax for the Treatment of Refractory or Recurrent Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma, The AVENUE-2 Trial

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT04941716

Sonrotoclax, Rituximab, and Zanubrutinib in Treating Participants With Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, and Mantle Cell Lymphoma

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated Apr 22, 2026 · NCT06839053

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

RecruitingPhase 4
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876662

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

RecruitingPhase 4
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876649

Study of SGR-1505 in Mature B-Cell Neoplasms

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT05544019

A Randomized Phase II Study Of Bruton Tyrosine Kinase Inhibitor With Or Without Venetoclax In Veterans With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)

RecruitingPhase 2
  • VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
Ages 18 to 80 · All sexes · Updated Oct 14, 2025 · NCT06520098

A Study of AC676 for the Treatment of Relapsed/Refractory B-Cell Malignancies

RecruitingPhase 1
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Oct 2, 2025 · NCT05780034

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.