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Breast Cancer clinical trials in Seattle, WA

40 studies for Breast Cancer are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

An Investigational Study of BG-75202 Alone and in Combination With Other Therapeutic Agents in Adults With Advanced Solid Tumors

RecruitingPhase 1
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222267

A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)

RecruitingPhase 3
  • Fred Hutchinson Cancer Center ( Site 0069), Seattle
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06966700

ASPEN-09-03: A Study of Evorpacept in Combination With Trastuzumab and Chemotherapy in Metastatic HER2-Positive Breast Cancer

RecruitingPhase 2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07007559

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

Recruiting
  • Fred Hutch Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07214532

A Study to Evaluate the Safety, Tolerability, Drug Levels, and Preliminary Efficacy of BMS-986507 Combinations in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Swedish Medical Center, Seattle
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT06618287

Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer

RecruitingPhase 3
  • Clinical Trial Site, Seattle
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07085767

ARTIDIS Nanomechanical Generated Measurements for Early Breast Lesions

Recruiting
  • University of Washington, Seattle
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06085833

A Study of Tersolisib (LY4064809/STX-478) With Other Anti-Cancer Treatments in Participants With Advanced Breast Cancer With a Genetic Change (PIK3CA)

RecruitingPhase 3
  • Swedish Medical Center, Seattle
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07174336

Beamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has Spread

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06324357

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Washington, Fred Hutchinson Cancer Center, Seattle
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence

RecruitingPhase 3
  • Virginia Mason Medical Center, Seattle
  • Swedish Cancer Institute, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT06492616

BGB-21447 (Bcl-2 Inhibitor) Combinations for Adults With Hormone-Receptor Positive (HR+)/Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Metastatic Breast Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06756932

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06625775

A Phase 1/1b Study of IAM1363 in HER2 Cancers

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT06253871

Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25

RecruitingPhase 3
  • Virginia Mason Medical Center, Seattle
  • Swedish Medical Center-Ballard Campus, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • and 5 more
Ages 18 to 60 · Women · Updated Sep 2, 2026 · NCT05879926

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Swedish Medical Center-Ballard Campus, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • and 1 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid Tumors

RecruitingPhase 1/2
  • Fred Hutch Cancer Research, Seattle
Ages 18 to 100 · All sexes · Updated Aug 27, 2026 · NCT06726148

Hippocampal Avoidance in Craniospinal Irradiation for the Treatment of Leptomeningeal Metastases From Breast Cancer or Non-small Cell Lung Cancer

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT06518057

Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

Recruiting
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT07140172

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Swedish Cancer Institute, Seattle
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Saint Joseph Medical Center Hematology and Oncology - Silverdale, Silverdale · 17 mi away
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers

RecruitingPhase 1
  • University Of Washington, Seattle
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • University of Washington School of Medicine, Seattle
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Jun 23, 2026 · NCT06993844

[18F]FTT Positron Emission Tomography for the Measurement of PARP Tumor Expression in Patients With Metastatic Breast Cancer

RecruitingPhase 1/2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · All sexes · Updated May 19, 2026 · NCT06502691

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

RecruitingPhase 3
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated May 18, 2026 · NCT06757634

A Study Evaluating the Safety, Pharmacokinetics and Early Efficacy of AVA6000 in Solid Tumours

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT04969835

De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)

RecruitingPhase 3
  • Swedish Medical Center-Ballard Campus, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • Saint Michael Cancer Center, Silverdale · 17 mi away
Ages 50 to 70 · All sexes · Updated Apr 23, 2026 · NCT04852887

Quantitative MRI Assessment of Breast Cancer Therapy Response

RecruitingObservational study
  • University of Washington, Seattle
Ages 18 and older · All sexes · Updated Apr 17, 2026 · NCT05704062

Avelumab or Hydroxychloroquine With or Without Palbociclib to Eliminate Dormant Breast Cancer

RecruitingPhase 2
  • University of Washington, Seattle
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT04841148

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Kaiser Permanente Washington, Seattle
  • Swedish Medical Center-First Hill, Seattle
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Seattle
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity

RecruitingPhase 3
  • FHCC South Lake Union, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • University of Washington Medical Center - Montlake, Seattle
Ages 18 and older · All sexes · Updated Oct 8, 2025 · NCT03418961

MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles

RecruitingObservational study
  • Swedish Cancer Institute, Seattle
  • Seattle Cancer Care Alliance, Seattle
Ages 18 and older · All sexes · Updated Aug 20, 2025 · NCT03053193

About Breast Cancer

Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. These extra cells can form a mass called a tumor.

More about Breast Cancer on MedlinePlus

Breast Cancer trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.