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Prostate Cancer clinical trials in Seattle, WA

44 studies for Prostate Cancer are looking for participants at sites in and around Seattle (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of JNJ-87189401 Combined With JNJ-78278343 for Advanced Prostate Cancer

RecruitingPhase 1
  • Swedish Medical Center, Seattle
Ages 18 and older · Men · Updated Sep 28, 2026 · NCT06095089

Precision-Based Genomics in Prostate Cancer

RecruitingObservational study
  • University of Washington, Seattle
Ages 18 to 120 · Men · Updated Sep 28, 2026 · NCT04706663

Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Research Center, Seattle
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT06801236

A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Sep 25, 2026 · NCT07082920

Study Comparing AAA817+ARPI Versus Standard of Care in Adult Participants With PSMA-positive mCRPC

RecruitingPhase 3
  • Swedish Medical Center, Seattle
Ages 18 to 100 · Men · Updated Sep 22, 2026 · NCT06855277

Carboplatin or Olaparib for BRcA Deficient Prostate Cancer

RecruitingPhase 2
  • VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT04038502

High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers

RecruitingPhase 2
  • VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT05011383

A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)

RecruitingPhase 3
  • VA Puget Sound Health Care System ( Site 0054), Seattle
  • Fred Hutchinson Cancer Center ( Site 0060), Seattle
Ages 18 and older · Men · Updated Sep 17, 2026 · NCT06925737

PROMISE Registry: A Prostate Cancer Registry of Outcomes and Germline Mutations for Improved Survival and Treatment Effectiveness

RecruitingObservational study
  • University of Washington Medical Center, Seattle
Ages 18 and older · Men · Updated Sep 15, 2026 · NCT04995198

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • University of Washington, Fred Hutchinson Cancer Center, Seattle
Ages 12 and older · All sexes · Updated Sep 15, 2026 · NCT04585750

The SUGAR Study; SBRT and Relugolix) for Prostate Cancer

RecruitingPhase 2
  • University of Washington, Seattle
Ages 18 and older · Men · Updated Sep 14, 2026 · NCT06111781

Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients With High Risk Prostate Cancer

RecruitingPhase 3
  • Fred Hutchinson Cancer Center, Seattle
  • FHCC at Northwest Hospital, Seattle
  • University of Washington Medical Center - Montlake, Seattle
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05946213

Safety, Pharmacokinetics, and Preliminary Efficacy of VIR-5500 (AMX-500) in Prostate Cancer

RecruitingPhase 1
  • Investigational Site Number: 400, Seattle
Ages 18 and older · Men · Updated Sep 10, 2026 · NCT05997615

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Swedish Medical Center-Ballard Campus, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • Swedish Medical Center-First Hill, Seattle
  • and 1 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Testing Different Dosing Schedules of the Anti-cancer Drug, Lutetium 177Lu PSMA RLT and Its Effect on Patients With Advanced Prostate Cancer, RECIPROCAL Trial

RecruitingPhase 3
  • Swedish Medical Center-First Hill, Seattle
Ages 18 and older · Men · Updated Sep 2, 2026 · NCT07200830

Targeted Treatment for Metastatic Prostate Cancer, The PREDICT Trial

RecruitingPhase 2
  • Swedish Medical Center-First Hill, Seattle
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT06632977

Prostate Active Surveillance Study

RecruitingObservational study
  • Veterans Affairs Puget Sound Health Care System, Seattle
  • University of Washington, Seattle
Ages 21 and older · Men · Updated Sep 2, 2026 · NCT00756665

Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Aug 27, 2026 · NCT07698535

A Single-Arm Phase II Study of Neoadjuvant Intensified Androgen Deprivation (Leuprolide and Abiraterone Acetate) in Combination With AKT Inhibition (Capivasertib) for High-Risk Localized Prostate Cancer With PTEN Loss

RecruitingPhase 2
  • VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle
Ages 18 and older · Men · Updated Aug 25, 2026 · NCT05593497

Study of Oral MRT-2359 With Apalutamide in Prostate Cancer

RecruitingPhase 2
  • University of Washington Medical Center, Seattle
Ages 18 and older · Men · Updated Aug 24, 2026 · NCT07745361

A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide

RecruitingPhase 2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT06844383

Study of AMG 509 in Participants With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Aug 21, 2026 · NCT04221542

Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging

RecruitingPhase 3
  • Swedish Medical Center-Ballard Campus, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • and 4 more
Ages 18 and older · Men · Updated Aug 19, 2026 · NCT04423211

A Study of FG-3246 in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC)

RecruitingPhase 2
  • Fred Hutchinson Cancer Center, Seattle
  • University of Washington Medical Center, Seattle
Ages 18 and older · Men · Updated Aug 17, 2026 · NCT06842498

Genomic Biomarker-Selected Umbrella Neoadjuvant Study for High Risk Localized Prostate Cancer

RecruitingPhase 2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Aug 14, 2026 · NCT04812366

Impact of DNA Repair Pathway Alterations on Sensitivity to Radium-223 in Bone Metastatic Castration-resistant Prostate Cancer

RecruitingObservational study
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Aug 12, 2026 · NCT04489719

Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 1/2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Aug 11, 2026 · NCT06236139

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Aug 10, 2026 · NCT06067841

Collecting and Studying Blood and Tissue Samples From Patients With Locally Recurrent or Metastatic Prostate or Bladder/Urothelial Cancer

RecruitingObservational studyHealthy volunteers welcome
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Aug 6, 2026 · NCT01050504

Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
All ages · Men · Updated Aug 6, 2026 · NCT06145633

Evaluation of Neoadjuvant Xaluritamig in Localized Prostate Cancer

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Jul 31, 2026 · NCT06613100

Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Jul 21, 2026 · NCT06039371

Exercise for Tumor Suppressive Impact in Men With Prostate Cancer at High-Risk of Progression on Active Surveillance: The REMOVE Trial

Recruiting
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Jul 15, 2026 · NCT05918263

Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response

RecruitingPhase 3
  • Swedish Medical Center-Ballard Campus, Seattle
  • Fred Hutchinson Cancer Center, Seattle
  • Swedish Medical Center-Cherry Hill, Seattle
  • and 4 more
Ages 18 and older · Men · Updated Jul 14, 2026 · NCT06592924

Study of ORIC-944 in Patients With Metastatic Prostate Cancer

RecruitingPhase 1
  • University of Washington, Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · Men · Updated Jul 9, 2026 · NCT05413421

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

RecruitingPhase 2
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 18 and older · Men · Updated Jul 7, 2026 · NCT06526299

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

RecruitingPhase 2
  • VA Puget Sound Health Care System, Seattle
Ages 18 and older · Men · Updated Jun 15, 2026 · NCT05422911

Prostate Cancer Screening for People at Genetic Risk for Aggressive Disease, PATROL Study

RecruitingObservational studyHealthy volunteers welcome
  • Fred Hutch/University of Washington Cancer Consortium, Seattle
Ages 40 and older · Men · Updated May 15, 2026 · NCT04472338

A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies

RecruitingPhase 1/2
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Fred Hutchinson Cancer Center, Seattle
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Carboplatin Chemotherapy Before Surgery for People With High-Risk Prostate Cancer and an Inherited BRCA1 or BRCA2 Gene Mutation

RecruitingPhase 2
  • Swedish Medical Center-Ballard Campus, Seattle
  • FHCC South Lake Union, Seattle
  • Fred Hutchinson Cancer Research Center, Seattle
  • and 4 more
Ages 18 and older · Men · Updated Jan 29, 2026 · NCT05806515

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Seattle
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer

RecruitingPhase 3
  • FHCC South Lake Union, Seattle
  • FHCC at Northwest Hospital, Seattle
  • University of Washington Medical Center - Montlake, Seattle
Ages 18 and older · Men · Updated Sep 11, 2025 · NCT03678025

About Prostate Cancer

Prostate cancer is one of the most common types of cancer among American men. The risk goes up as men age. Learn about symptoms, tests, and treatment.

More about Prostate Cancer on MedlinePlus

Prostate Cancer trials in other cities

Other studies in Seattle

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.