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Colorectal Cancer clinical trials in Minnesota
45 studies for Colorectal Cancer are looking for participants at sites in Minnesota.
Cities in Minnesota
- Rochester29 studies
- Minneapolis19 studies
- Saint Paul9 studies
- Plymouth9 studies
- Brooklyn Park7 studies
- Bloomington7 studies
- Duluth5 studies
Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial
- Sanford Joe Lueken Cancer Center, Bemidji
- Regions Hospital, Saint Paul
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT05673148Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
- Riverwood Healthcare Center, Aitkin
- Mayo Clinic Health System in Albert Lea, Albert Lea
- Essentia Health - Baxter Clinic, Baxter
- and 48 more
RecruitingObservational studyHealthy volunteers welcome
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069Family Communications After Genetic Testing
- Riverwood Healthcare Center, Aitkin
- Essentia Health - Baxter Clinic, Baxter
- Essentia Health Saint Joseph's Medical Center, Brainerd
- and 41 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07143487Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors
- Exelixis Clinical Site #68, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483PRE-ISPY Phase I/II Oncology Platform Program
- University of Minnesota Masonic Cancer Center, Minneapolis
- Mayo Clinic Comprehensive Cancer Center, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
- Avera Cancer Institute- Marshall, Marshall
- Mayo Clinic Hospital, Methodist Campus, Research Pharmacy, Rochester
- Mayo Clinic Pharmacy, Rochester
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing
- Mayo Clinic Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial
- University of Minnesota/Masonic Cancer Center, Minneapolis
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
- Minnesota Oncology, Maple Grove
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07221357Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors
- Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
- Mayo Clinic - Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies
- Masonic Cancer Center University of Minnesota, Minneapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924An Investigational Drug (TPST-1495) in Patients With Familial Adenomatous Polyposis
- Mayo Clinic in Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06557733A Study Evaluating the Safety and Efficacy of Targeted Therapies in Subpopulations of Patients With Metastatic Colorectal Cancer (INTRINSIC)
- Mayo Clinic Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT04929223A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)
- Minnesota Oncology Hematology, P.A., Saint Louis Park
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07549412Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
- Clinical Study Site, Saint Louis Park
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors
- University of Minnesota Masonic Cancer Center, Minneapolis
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07216105The Vanguard Study: Testing a New Way to Screen for Cancer
- Minneapolis VA Medical Center, Minneapolis
RecruitingHealthy volunteers welcome
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors
- University of Minnesota/Masonic Cancer Center, Minneapolis
RecruitingPhase 1/2
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119A Study of Novel Study Interventions and Combinations in Participants With Colorectal Cancer
- Research Site, Rochester
RecruitingPhase 2
Ages 18 to 130 · All sexes · Updated Aug 18, 2026 · NCT06792695Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients
- Mayo Clinic, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT05410977FOG-001 in Locally Advanced or Metastatic Solid Tumors
- M Health Fairview University of Minnesota Medical Center, Minneapolis
- Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)
- M Health Fairview University of Minnesota Medical Center, Minneapolis
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064Study of RAS(ON) Inhibitors in Combination With Ivonescimab in Patients With Solid Tumors
- Health Partners Cancer Center at Regions Hospital, Saint Paul
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT07397338A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors
- Minnesota Oncology Hematology, Maple Grove
- Mayo Clinic (Minnesota), Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
- Mayo Clinic Rochester, Rochester
RecruitingPhase 1
Ages 18 to 100 · All sexes · Updated Jul 29, 2026 · NCT06562192A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer
- Minnesota Oncology Hematology, PA, Burnsville
- Allina Health Cancer institute, Coon Rapids
- Minnesota Oncology Hematology, PA, Coon Rapids
- and 17 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651A Study of SGN-CEACAM5C in Adults With Advanced Solid Tumors
- Mayo Clinic Cancer Center, Rochester
- Mayo Clinic, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06131840A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer
- May Clinic Rochester, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 16, 2026 · NCT06948448A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease
- Scri Minnesota Oncology Hematology, P.A. /ID# 275149, Minneapolis
- Mayo Clinic-Rochester /ID# 273508, Rochester
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT07023289Lead-212 PSV359 Therapy for Patients With Solid Tumors
- Mayo Clinic in Rochester, Minnesota, Rochester
RecruitingPhase 1/2
Ages 18 to 90 · All sexes · Updated Jul 6, 2026 · NCT06710756A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
- Mayo Clinic Rochester, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)
- Minnesota Oncology Hematology - Primary, Maple Grove
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT07011576KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors
- Mayo Clinic Comprehensive Cancer Center, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410A Study to Investigate the Safety and Efficacy of KQB365 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies
- Mayo Clinic, Rochester, Rochester
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06720987Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors
- Riverwood Healthcare Center, Aitkin
- Essentia Health - Baxter Clinic, Baxter
- Essentia Health Saint Joseph's Medical Center, Brainerd
- and 38 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869A Study of PARG Inhibitor ETX-19477 in Patients With Advanced Solid Malignancies
- Mayo Clinic, Rochester
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Mar 27, 2026 · NCT06395519Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
- Mayo Clinic Health System in Albert Lea, Albert Lea
- Essentia Health Saint Joseph's Medical Center, Brainerd
- Minnesota Oncology - Burnsville, Burnsville
- and 31 more
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform
- Mayo Clinic in Rochester, Rochester
RecruitingObservational study
Ages 18 and older · All sexes · Updated Mar 12, 2026 · NCT06349642cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease
- Allina Health Cancer Institute, Minneapolis
- Mayo Clinic, Rochester
RecruitingObservational studyHealthy volunteers welcome
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.