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Colorectal Cancer clinical trials in Minneapolis, MN

19 studies for Colorectal Cancer are looking for participants at sites in and around Minneapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • University of Minnesota/Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Masonic Cancer Center University of Minnesota, Minneapolis
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05786924

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

RecruitingPhase 3
  • Minnesota Oncology Hematology, P.A., Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07549412

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • University of Minnesota Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05868226

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Minneapolis VA Medical Center, Minneapolis
Ages 45 to 75 · All sexes · Updated Sep 2, 2026 · NCT06995898

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • University of Minnesota Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07216105

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • University of Minnesota/Masonic Cancer Center, Minneapolis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • M Health Fairview University of Minnesota Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05919264

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • M Health Fairview University of Minnesota Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Allina Health Cancer Institute (Virginia Piper Cancer Institute), Minneapolis
  • Minnesota Oncology Hematology, PA, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • and 3 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Allina Health Cancer Institute, Minneapolis
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 60 and older · All sexes · Updated Jan 8, 2026 · NCT03998202

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Minneapolis

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.