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Colorectal Cancer clinical trials in Minneapolis, MN

20 studies for Colorectal Cancer are looking for participants at sites in and around Minneapolis (within about 30 miles). Open a study to see who can join and how to contact the study team.

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The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Minneapolis VA Medical Center, Minneapolis
Ages 45 to 75 · All sexes · Updated Nov 6, 2026 · NCT06995898

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Nov 6, 2026 · NCT07018869

Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 60 and older · All sexes · Updated Nov 5, 2026 · NCT03998202

A Study of Precemtabart Tocentecan With or Without Bevacizumab Compared to Trifluridine/Tipiracil Plus Bevacizumab in Participants With Previously Treated Metastatic Colorectal Cancer (PROCEADE-CRC-03)

RecruitingPhase 3
  • Minnesota Oncology Hematology, P.A., Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07549412

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Minneapolis
  • Clinical Study Site, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT07228832

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 40 to 75 · All sexes · Updated Nov 4, 2026 · NCT05334069

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Nov 4, 2026 · NCT06418204

Family Communications After Genetic Testing

RecruitingHealthy volunteers welcome
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07143487

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur Trial

RecruitingPhase 2
  • University of Minnesota/Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT05673148

SumMET: Study of [225Ac]Ac-FL-261 in Participants With Solid Tumors Overexpressing c-MET

RecruitingPhase 1/2
  • Full-Life Technologies Investigational Site, Minneapolis
Ages 18 and older · All sexes · Updated Oct 29, 2026 · NCT07873450

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • M Health Fairview University of Minnesota Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Oct 26, 2026 · NCT06330064

Phase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive Malignancies

RecruitingPhase 1/2
  • Masonic Cancer Center University of Minnesota, Minneapolis
Ages 18 and older · All sexes · Updated Oct 13, 2026 · NCT05786924

FOG-001 in Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • M Health Fairview University of Minnesota Medical Center, Minneapolis
Ages 18 and older · All sexes · Updated Oct 7, 2026 · NCT05919264

PRE-ISPY Phase I/II Oncology Platform Program

RecruitingPhase 1/2
  • University of Minnesota Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT05868226

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • University of Minnesota/Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • University of Minnesota Masonic Cancer Center, Minneapolis
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07216105

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • University of Minnesota/Masonic Cancer Center, Minneapolis
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Allina Health Cancer Institute (Virginia Piper Cancer Institute), Minneapolis
  • Minnesota Oncology Hematology, PA, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • and 3 more
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

LOTUS-CC: An Observational Research Study to Uncover Subtypes of Cancer Cachexia

RecruitingObservational study
  • Abbott-Northwestern Hospital, Minneapolis
  • Hennepin County Medical Center, Minneapolis
  • Park Nicollet Clinic - Saint Louis Park, Saint Louis Park · 5 mi away
Ages 18 and older · All sexes · Updated Jan 9, 2026 · NCT06073431

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Minneapolis

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.