🔎 Trials Near Me

Home › Charleston, SC

Healthy volunteer studies in Charleston, SC

57 studies at sites in and around Charleston accept healthy volunteers — people without the condition being studied. Many studies pay participants for their time and travel; the amount is set by each study, so ask the study team.

Investigating Novel Smoking Cessation Primary Care Interventions in Rural Environments

RecruitingHealthy volunteers welcomeMentions payment for participants
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT05764759

Lot-to-lot Consistency Study of a 21-valent Pneumococcal Conjugate Vaccine in Healthy Infants From 2 Months of Age

RecruitingPhase 3Healthy volunteers welcome
  • Tribe Clinical Research At Neighbors Pediatrics- Site Number : 8400008, Charleston
42 Days – 89 Days · All sexes · Updated Oct 5, 2026 · NCT07348692

A Clinical Study of Novel Pneumococcal Vaccine V118C in Children (V118C-002)

RecruitingPhase 1Healthy volunteers welcome
  • Carolina Family Care ( Site 1021), Charleston
2 Months – 15 Months · All sexes · Updated Oct 2, 2026 · NCT07300267

Surgical Thromboprophylaxis Practices in Oncology Patients Within the NCORP Network, STOP-VTE Study

RecruitingObservational studyHealthy volunteers welcome
  • Charleston Oncology North Charleston, Charleston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07215624

Testing an Enhanced Digital Delivery Model for Inherited Cancer Genetic Testing in Young Adults With Cancer

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT07091617

Observational Study of Decentralized Urine Optical Interaction Patterns Associated With Environmental Microplastic and Nanoplastic Exposure

RecruitingObservational studyHealthy volunteers welcome
  • Decentralized / At-Home Participation (U.S.), Charleston
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07775495

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 55 and older · All sexes · Updated Sep 28, 2026 · NCT06112418

GBPDC: Gut-Brain in PD Consortium Master Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 21 to 80 · All sexes · Updated Sep 25, 2026 · NCT07567794

American Lung Association (ALA) Lung Health Cohort

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 25 to 35 · All sexes · Updated Sep 23, 2026 · NCT04543461

Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06279013

Development and Evaluation of a Virtual Reality Tool for At-Risk Trauma-Exposed Young People

RecruitingHealthy volunteers welcome
  • National Crime Victims Research and Treatment Center, Charleston
Ages 15 to 30 · All sexes · Updated Sep 9, 2026 · NCT05816083

STEPS: Substance Use Trial of E-cigarettes or Pharmacotherapy for Smoking

RecruitingHealthy volunteers welcome
  • MUSC Charleston, Charleston
Ages 21 and older · All sexes · Updated Sep 3, 2026 · NCT06922617

Pragmatic Evaluation of Events And Benefits of Lipid-lowering in Older Adults

RecruitingPhase 4Healthy volunteers welcome
  • Charleston VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
Ages 75 and older · All sexes · Updated Sep 1, 2026 · NCT04262206

Health Education Approach to Lung Screening

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 50 to 80 · All sexes · Updated Aug 25, 2026 · NCT06070870

Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Aug 20, 2026 · NCT06678789

Social Functioning in Opioid Use Disorder

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07044466

Progesterone Preeclampsia

RecruitingPhase 4Healthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · Women · Updated Aug 17, 2026 · NCT07448597

A Clinical Trial of Adaptive Treatment for Early Smoking Cessation Relapse

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Aug 12, 2026 · NCT06118502

COPEWeb Training for Providers

RecruitingHealthy volunteers welcome
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05812131

Systemic Lupus Erythematosus in Gullah Health

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 2 and older · All sexes · Updated Jul 28, 2026 · NCT00756769

RECOVERS - Realigning Emotion and COgnition Via prEcision Regulation networkS

RecruitingHealthy volunteers welcome
  • Medical Univeristy of South Carolina, Charleston
Ages 18 to 65 · All sexes · Updated Jul 21, 2026 · NCT05977439

Impact of Cigarette and E-cigarette Menthol Regulation on Current Smokers of Menthol Cigarettes

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Jul 21, 2026 · NCT05896033

Switch or Quit R01

RecruitingHealthy volunteers welcome
  • Medical Univeristy of South Carolina, Charleston
Ages 21 and older · All sexes · Updated Jul 13, 2026 · NCT06373679

Digitally Enhanced Stepped-Care for Depression in Primary Care

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Jul 9, 2026 · NCT07634705

Atomoxetine and Executive Function in PTSD

RecruitingPhase 4Healthy volunteers welcome
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 to 75 · All sexes · Updated Jul 7, 2026 · NCT06573970

Young Adult Tobacco/Nicotine and Cannabis Co-use

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina - Charleston, Charleston
Ages 18 to 25 · All sexes · Updated Jul 6, 2026 · NCT06239350

Advanced SPinal Innovations With Robotics and Enabling Technology Registry

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina Shawn Jenkins Children's Hospital, Charleston
Ages 0 to 21 · All sexes · Updated Jun 22, 2026 · NCT05071144

E-cigarette Cessation in Adults Who Co-use Cannabis

RecruitingPhase 4Healthy volunteers welcome
  • MUSC Charleston, Charleston
Ages 18 to 40 · All sexes · Updated Jun 12, 2026 · NCT06688539

The Society for Obstetric Anesthesia and Perinatology Research Network General Anesthesia Registry

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 15 to 55 · Women · Updated Jun 4, 2026 · NCT06030063

A Study on the Immune Response and Safety of an Investigational Chickenpox Vaccine When Given to Healthy Children 12 to 15 Months of Age

RecruitingPhase 3Healthy volunteers welcome
  • GSK Investigational Site, Charleston
  • GSK Investigational Site, Charleston
12 Months – 15 Months · All sexes · Updated May 29, 2026 · NCT06740630

tFUS Induced Transient Scotoma for Individual Dosing

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina Brain Stimulation Division, Charleston
Ages 18 to 70 · All sexes · Updated May 29, 2026 · NCT06426498

Cognitive Decline Following Deep Brain Stimulation

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated May 29, 2026 · NCT05822388

Weekly Isotretinoin vs Tetracycline for Moderate Acne

RecruitingEarly phase 1Healthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 12 and older · All sexes · Updated May 18, 2026 · NCT06225570

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

RecruitingPhase 3Healthy volunteers welcome
  • Lowcountry Center for Veterans Research, Charleston
Ages 18 and older · All sexes · Updated Apr 29, 2026 · NCT07280065

A Pilot Study of a Remote ADHD Monitoring Program

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 5 to 11 · All sexes · Updated Apr 28, 2026 · NCT06743425

RTMS Targets Neural Circuits for Smoking Cessation

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
  • Medical University of South Carolina, Charleston
Ages 22 to 70 · All sexes · Updated Apr 16, 2026 · NCT04903028

HVIP Outcomes and Stakeholder Insights

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 16 and older · All sexes · Updated Apr 9, 2026 · NCT06582953

Cannabis-Tobacco Co-Use Treatment Study

RecruitingPhase 3Healthy volunteers welcome
  • Medical University of South Carolina - Charleston, Charleston
Ages 18 and older · All sexes · Updated Apr 3, 2026 · NCT06883162

Evaluating Whether an Educational Website Called Current Together After Cancer (CTAC) Improves Follow-up Care for Colorectal Cancer Survivors

RecruitingPhase 3Healthy volunteers welcome
  • Ralph H Johnson VA Medical Center, Charleston
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Mar 31, 2026 · NCT07018869

Helix Research Network

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina (In Our DNA SC), Charleston
Ages 18 and older · All sexes · Updated Mar 23, 2026 · NCT06057181

3D-Printed Versus Laboratory-Fabricated Hyrax Expanders

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 8 to 13 · All sexes · Updated Mar 20, 2026 · NCT05743127

Enhancing Smoking Cessation Via Telehealth Options in Primary Care

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT05493254

Black and African Americans Connections to Parkinson's Disease (BLAAC PD)

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Feb 27, 2026 · NCT06719583

taVNS-Paired Breastfeeding to Improve Breastfeeding at Discharge

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina Shawn Jenkins Children's Hospital, Charleston
35 Weeks · All sexes · Updated Feb 6, 2026 · NCT06417385

Beat Childhood Cancer Specimen Banking and Data Registry

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
All ages · All sexes · Updated Feb 3, 2026 · NCT04715178

Caris Biorepository Research Protocol

RecruitingObservational studyHealthy volunteers welcome
  • Clinical Biotechnology Research Institute at RSFH, Charleston
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT01499394

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

RM1 Project 2 - tAN fMRI

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina Institute of Psychiatry, Charleston
Ages 18 to 65 · All sexes · Updated Dec 18, 2025 · NCT05487664

RM1 Project 1 - tAN Naloxone

RecruitingEarly phase 1Healthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 to 65 · All sexes · Updated Dec 18, 2025 · NCT05490134

SMYLS Multi-site Trial

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 14 to 21 · All sexes · Updated Dec 8, 2025 · NCT06035939

A Study to Evaluate the SENSE Device's Ability to Detect TBI

RecruitingObservational studyHealthy volunteers welcome
  • MUSC, Charleston
Ages 22 and older · All sexes · Updated Nov 25, 2025 · NCT06828107

Impact of Nd:YAG Laser Photobiostimulation on Healing of Gingiva

RecruitingHealthy volunteers welcome
  • MUSC College of Dental Medicine, Graduate Periodontics Clinic, Charleston
Ages 18 and older · All sexes · Updated Nov 12, 2025 · NCT07095556

ACTION: Trial of Adding Buprenorphine, CBT, and TMS to Improve Outcomes of Long-Term Opioid Therapy for Chronic Pain

RecruitingPhase 1/2Healthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Nov 5, 2025 · NCT06442566

Quantitative Cardiac Parametric Mapping

RecruitingHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 to 90 · All sexes · Updated Nov 5, 2025 · NCT02855554

Cognitive Decline Following Deep Brain Stimulation: A DBS-fMRI Study

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
Ages 18 and older · All sexes · Updated Oct 14, 2025 · NCT06960096

EMG-Controlled Game to Retrain Upper Extremity Muscle Activation Patterns Following Stroke

RecruitingHealthy volunteers welcome
  • Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston
Ages 18 and older · All sexes · Updated Aug 26, 2025 · NCT05628324

Project Mountain - Comparing SpO2 and SaO2 for Accuracy

RecruitingObservational studyHealthy volunteers welcome
  • Medical University of South Carolina, Charleston
All ages · All sexes · Updated Apr 2, 2025 · NCT06372106

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.