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Chronic Lymphocytic Leukemia clinical trials in Philadelphia, PA

11 studies for Chronic Lymphocytic Leukemia are looking for participants at sites in and around Philadelphia (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

Testing the Addition of Anti-Cancer Drug Sonrotoclax, to the Standard Treatment Zanubrutinib, for Previously Untreated CLL/SLL

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Torresdale Hospital, Philadelphia
Ages 65 and older · All sexes · Updated Oct 2, 2026 · NCT07321652

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Reading Hospital McGlinn Cancer Institute at Phoenixville, Phoenixville · 22 mi away
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Testing Early Treatment for Patients With High-Risk Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Leukemia (SLL), EVOLVE CLL/SLL Study

RecruitingPhase 3
  • Thomas Jefferson University Hospital, Philadelphia
  • Jefferson Torresdale Hospital, Philadelphia
  • Asplundh Cancer Pavilion, Willow Grove · 13 mi away
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT04269902

A Study of Nemtabrutinib (MK-1026) Versus Comparator (Investigator's Choice of Ibrutinib or Acalabrutinib) in First Line (1L) Chronic Lymphocytic Leukemia (CLL)/ Small Lymphocytic Lymphoma (SLL) (MK-1026-011/BELLWAVE-011)

RecruitingPhase 3
  • Consultants in Medical Oncology and Hematology (CMOH) ( Site 8002), Broomall · 10 mi away
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06136559

A Study of AZD0486 Monotherapy or in Combination With Other Anti-Cancer Agents for Mature B-Cell Malignancies

RecruitingPhase 1/2
  • Research Site, Philadelphia
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06564038

A Study of NX-5948 in Adults With Relapsed/Refractory B-cell Malignancies

RecruitingPhase 1
  • University of Pennsylvania, Abramson Cancer Center, Philadelphia
Ages 18 and older · All sexes · Updated Jul 2, 2026 · NCT05131022

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

RecruitingPhase 4
  • University of Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876662

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

RecruitingPhase 4
  • University of Pennsylvania Hospital, Philadelphia
Ages 18 and older · All sexes · Updated Mar 2, 2026 · NCT06876649

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

RecruitingPhase 2
  • Pennsylvania Oncology Hematolo /ID# 249637, Philadelphia
Ages 18 and older · All sexes · Updated Feb 9, 2026 · NCT04895436

Chronic Lymphocytic Leukemia trials in other cities

Other studies in Philadelphia

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.