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Lung Cancer clinical trials in Tampa, FL

29 studies for Lung Cancer are looking for participants at sites in and around Tampa (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Chemotherapy Combined With Immunotherapy Versus Immunotherapy Alone for Older Adults With Stage IIIB-IV Lung Cancer, The ACHIEVE Trial

RecruitingPhase 3
  • Moffitt Cancer Center-International Plaza, Tampa
  • James A. Haley Veterans Affairs Hospital, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • and 1 more
Ages 70 and older · All sexes · Updated Oct 5, 2026 · NCT06096844

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
Ages 40 to 75 · All sexes · Updated Oct 2, 2026 · NCT05334069

Immunotherapy After Surgery for People Who Have No Remaining Cancer Cells After Standard Treatment for Early-Stage Non-Small Cell Lung Cancer, INSIGHT Trial

RecruitingPhase 3
  • Moffitt Cancer Center-International Plaza, Tampa
  • Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • and 1 more
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06498635

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

Neladalkib (NVL-655) for TKI-naive Patients With Advanced ALK-Positive NSCLC

RecruitingPhase 3
  • H Lee Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Sep 30, 2026 · NCT06765109

Safety, Efficacy, and Pharmacokinetics of BNT327 in Combination With Chemotherapy and Other Investigational Agents for Lung Cancer

RecruitingPhase 2/3
  • H. Lee Moffit Cancer center and research institute, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06712316

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

A First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS Mutations

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07629960

Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT05681780

Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation

RecruitingPhase 1/2
  • Moffitt Cancer Center-International Plaza, Tampa
  • Moffitt Cancer Center - McKinley Campus, Tampa
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07012031

AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)

RecruitingPhase 1/2
  • Avenzo Therapeutics Recruiting Site, Tampa
Ages 18 to 75 · All sexes · Updated Sep 4, 2026 · NCT07038343

Testing the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung Cancer

RecruitingPhase 3
  • Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05624996

Study of RAS(ON) Inhibitors in Patients With Advanced RAS-mutated NSCLC

RecruitingPhase 1/2
  • H Lee Moffitt Cancer Center and Research Institute, Tampa
Ages 18 and older · All sexes · Updated Jun 30, 2026 · NCT06162221

A Phase 1 Dose-escalation Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation

RecruitingPhase 1
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07458347

Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer

RecruitingPhase 2
  • H Lee Moffitt Cancer Center and Research Institute, Tampa
Ages 18 to 70 · All sexes · Updated Jun 26, 2026 · NCT04614103

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT05642572

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Lee Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Targeted Treatment for Advanced Non-Small Cell Lung Cancer That Has a MET Exon 14 Skipping Gene Change (An Expanded Lung-MAP Treatment Trial)

RecruitingPhase 2
  • Moffitt Cancer Center, Tampa
18 Minutes · All sexes · Updated May 5, 2026 · NCT06031688

Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers

RecruitingHealthy volunteers welcome
  • Moffitt Cancer Center, Tampa
Ages 18 and older · All sexes · Updated Mar 5, 2026 · NCT06196008

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Tampa
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Lung Cancer

Lung cancer forms in tissues of the lung, usually in the cells that line the air passages. It is the leading cause of cancer death in both men and women.

More about Lung Cancer on MedlinePlus

Lung Cancer trials in other cities

Other studies in Tampa

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.