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Ovarian Cancer clinical trials in Nashville, TN

49 studies for Ovarian Cancer are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

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Testing the Addition of Paclitaxel Administered Into the Abdominal Cavity Combined With Chemotherapy for Patients With Gastric Cancer Spread to the Abdominal Cavity

RecruitingPhase 2/3
  • Vanderbilt University/Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT07001748

Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial

RecruitingPhase 2
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
  • Vanderbilt University/Ingram Cancer Center, Nashville
All ages · All sexes · Updated Oct 5, 2026 · NCT05564377

A Study of PHST001 in Advanced Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 18 and older · All sexes · Updated Oct 5, 2026 · NCT06840886

A Phase 1 Study of PLN-101095 in Adults With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06270706

A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
  • Tennessee Oncology PLLC, Nashville
Ages 18 and older · All sexes · Updated Oct 2, 2026 · NCT06465069

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06172478

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 19 and older · All sexes · Updated Oct 1, 2026 · NCT06586957

A Study of NT-175 in Adult Participants With Advanced Malignancies That Are Positive for HLA-A*02:01 and the TP53 R175H Mutation

RecruitingPhase 1
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT05877599

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Solid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell Manufacturing

RecruitingObservational study
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT04981119

Study of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)

RecruitingPhase 2
  • Research Site, Nashville
Ages 18 to 130 · All sexes · Updated Sep 23, 2026 · NCT05489211

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

RecruitingPhase 3
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213804

Study of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institue, Nashville
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06128551

Evaluate BL-B01D1 in Patients With Metastatic or Unresectable Non-Small Cell Lung Cancer (NSCLC) and Other Solid Tumors

RecruitingPhase 1
  • Sarah Cannon - Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT05983432

A Clinical Trial of Sac-TMT in People With Non-HRD Positive Advanced Ovarian Cancer (MK-2870-021)

RecruitingPhase 3
  • Henry-Joyce Cancer Clinic ( Site 0011), Nashville
Ages 18 and older · Women · Updated Sep 17, 2026 · NCT07318558

A Phase 1/2 Trial of TER-2013 in Patients With Solid Tumors Harboring AKT/PI3K/PTEN Pathway Alterations

RecruitingPhase 1/2
  • Sarah Cannon Nashville, Nashville
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07109726

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06293898

Phase 1 Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Antitumor Activity of ARR-002 in Advanced or Metastatic Ovarian or Endometrial Cancer.

RecruitingPhase 1
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · Women · Updated Sep 3, 2026 · NCT07755436

Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 15 and older · All sexes · Updated Aug 25, 2026 · NCT06276491

A Phase 1 Study of NRM-823 in Participants With Locally Advanced or Metastatic Refractory Solid Tumors

RecruitingPhase 1
  • Normunity Investigational Site, Nashville
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07182149

A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT04895709

A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
  • Vanderbilt University/Ingram Cancer Center, Nashville
  • Vanderbilt-Ingram Cancer Center at Franklin, Franklin · 17 mi away
  • and 1 more
Ages 35 to 50 · Women · Updated Aug 7, 2026 · NCT04251052

Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer

RecruitingPhase 3
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
  • Vanderbilt University/Ingram Cancer Center, Nashville
  • Vanderbilt-Ingram Cancer Center at Franklin, Franklin · 17 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT06580314

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)

RecruitingPhase 1/2
  • Sarah Cannon Research Institute at Tennessee Oncology, Nashville
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Aug 4, 2026 · NCT05579366

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • SCRI Oncology Partners, Nashville
  • Vanderbilt Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations

RecruitingPhase 2
  • SCRI - TriStar Medical Group Children's Specialists, Nashville
  • SCRI Oncology Partners, Nashville
Ages 8 and older · All sexes · Updated Jul 27, 2026 · NCT05503797

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

RecruitingPhase 1
  • Investigative Site #102, Nashville
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06545942

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

RecruitingPhase 2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06695845

First-in-Human Study of Tersolisib (STX-478) as Monotherapy and in Combination With Other Antineoplastic Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute, Nashville
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT05768139

A Study of Sigvotatug Vedotin in Advanced Solid Tumors

RecruitingPhase 1
  • US Oncology Research LLC, Nashville
Ages 18 and older · All sexes · Updated Jul 6, 2026 · NCT04389632

Study of Trastuzumab Deruxtecan With Bevacizumab Versus Bevacizumab Monotherapy for First-line Maintenance in HER2-Expressing Ovarian Cancer (DESTINY-Ovarian01)

RecruitingPhase 3
  • Sarah Cannon Research Institute (Oncology Associates of Oregon PC), Nashville
Ages 18 and older · Women · Updated Jul 2, 2026 · NCT06819007

A Study of Emiltatug Ledadotin (Emi-Le) in Participants With Solid Tumors

RecruitingPhase 1/2
  • Sarah Cannon Research Institute (SCRI), Nashville
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT05377996

A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression

RecruitingPhase 1/2
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT06051695

Study of NMS-03305293 in Adult Patients With Relapsed Ovarian Cancer

RecruitingPhase 1
  • Tennessee Oncology, Nashville
Ages 18 and older · Women · Updated May 28, 2026 · NCT06930755

JAB-30355 in Patients With Advanced Solid Tumors Harboring TP53 Y220C Mutation

RecruitingPhase 1/2
  • Research Site, Nashville
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT06386146

Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer

RecruitingPhase 3
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · Women · Updated Apr 16, 2026 · NCT05659381

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Sarah Cannon Research Institute (SCRI) Oncology Partners, Nashville
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

cfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual Disease

RecruitingObservational studyHealthy volunteers welcome
  • Vanderbilt-Ingram Cancer Center, Nashville
Ages 40 and older · All sexes · Updated Jan 20, 2026 · NCT05366881

A Study of CUSP06 in Patients With Platinum-Refractory/Resistant Ovarian Cancer and Other Advanced Solid Tumors

RecruitingPhase 1
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated Jan 14, 2026 · NCT06234423

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Nashville
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

A Study to Evaluate TROP2 ADC LCB84 Single Agent and in Combination With an Anti-PD-1 Ab in Advanced Solid Tumors

RecruitingPhase 1/2
  • Tennessee Oncology, Nashville
Ages 18 and older · All sexes · Updated Sep 24, 2025 · NCT05941507

A Phase 1 Study of XL309 (ISM3091) Alone and in Combination in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #6, Nashville
Ages 18 and older · All sexes · Updated Sep 5, 2025 · NCT05932862

A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies

RecruitingPhase 1/2
  • SCRI Oncology Partners, Nashville
Ages 18 and older · All sexes · Updated May 1, 2025 · NCT04503265

About Ovarian Cancer

Ovarian cancer is a cancerous tumor that forms in the tissues of an ovary. The ovaries are a pair of female reproductive glands that make eggs and female hormones.

More about Ovarian Cancer on MedlinePlus

Ovarian Cancer trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.