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Pancreatic Cancer clinical trials in Durham, NC

24 studies for Pancreatic Cancer are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Vanguard Study: Testing a New Way to Screen for Cancer

RecruitingHealthy volunteers welcome
  • Durham VA Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 45 to 75 · All sexes · Updated Oct 5, 2026 · NCT06995898

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Durham
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Durham
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

A Study to Learn About the Medicine Ponsegromab in Adults With Cancer of the Pancreas Which Has Spread and Caused Significant Body Weight Loss and Fatigue

RecruitingPhase 2/3
  • UNC Hospitals, The University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
  • University of North Carolina Hospitals at Hillsborough, Hillsborough · 13 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06989437

Study of Daraxonrasib (RMC-6236) in Patients With Resected Pancreatic Ductal Adenocarcinoma (PDAC)

RecruitingPhase 3
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07252232

A Study to Evaluate Chemotherapy With or Without INCB161734 in Previously Untreated, KRAS G12D-Mutated Metastatic Pancreatic Ductal Adenocarcinoma

RecruitingPhase 3
  • Investigative Site US035, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07522073

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

RecruitingPhase 1/2
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06445062

A Study of BMS-986504 Monotherapy and in Combination With Other Agents in Participants With Advanced and/or Metastatic Solid Tumors With Homozygous MTAP Deletion (MountainTAP-5)

RecruitingPhase 2
  • Local Institution - 0100, Durham
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07492680

Promoting CT Engagement for Pancreatic Cancer With App

Recruiting
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06252545

Comparing the Clinical Impact of Pancreatic Cyst Surveillance Programs and Associated Biomarkers

RecruitingObservational study
  • Durham VA Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
  • University of North Carolina-Hillsborough Campus, Hillsborough · 13 mi away
Ages 50 to 75 · All sexes · Updated Sep 4, 2026 · NCT04239573

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

RecruitingPhase 2
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07644559

Phase 1 Study of MRTX1719 in Solid Tumors With MTAP Deletion

RecruitingPhase 1
  • University of North Carolina - Gastroenterology and Hepatology, Chapel Hill · 10 mi away
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05245500

Testing Higher Dose Radiation Therapy for Locally Advanced Pancreatic Cancer

RecruitingPhase 3
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT06958328

Ulixertinib/Palbociclib in Patients With Advanced Pancreatic and Other Solid Tumors

RecruitingPhase 1
  • Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 to 99 · All sexes · Updated Aug 19, 2026 · NCT03454035

Safely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing Chemotherapy

RecruitingPhase 2
  • Duke University Medical Center, Durham
Ages 18 and older · All sexes · Updated Jul 15, 2026 · NCT06937177

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Durham
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Autologous CAR-T Cells Targeting B7-H3 in PDAC

RecruitingPhase 1
  • University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06158139

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Basal-like PDAC Treated With Gemcitabine, Erlotinib, and Nab-paclitaxel

RecruitingPhase 1/2
  • University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT06483555

Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer

RecruitingPhase 2
  • University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 to 99 · All sexes · Updated Jan 13, 2026 · NCT03977233

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

RecruitingPhase 2
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224

About Pancreatic Cancer

The pancreas is a gland behind your stomach that produces insulin. Pancreatic cancer is hard to catch early. Find out about risk factors and symptoms.

More about Pancreatic Cancer on MedlinePlus

Pancreatic Cancer trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 6, 2026. Each study sets its own eligibility; the study team decides who can join.