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Acute Lymphoblastic Leukemia clinical trials in Chicago, IL

19 studies for Acute Lymphoblastic Leukemia are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation

RecruitingPhase 1/2
  • The University of Chicago Medical Center, Chicago
30 Days · All sexes · Updated Sep 16, 2026 · NCT04065399

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Mount Sinai Hospital Medical Center, Chicago
  • John H Stroger Jr Hospital of Cook County, Chicago
  • University of Illinois, Chicago
  • and 1 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

RecruitingPhase 1/2
  • Lurie Children's Hospital-Chicago, Chicago
  • University of Illinois, Chicago
  • University of Chicago Comprehensive Cancer Center, Chicago
Up to age 22 · All sexes · Updated Aug 25, 2026 · NCT04726241

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

RecruitingPhase 2
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

A Study of CTD402 in T-ALL/LBL Patients

RecruitingPhase 1/2
  • University of Chicago, Chicago
Ages 1 and older · All sexes · Updated Aug 19, 2026 · NCT07070219

Safety Study to Evaluate the Occurrence of EFAD in Pediatric Patients With PNAC Who Require More Than Eight Weeks of Omegaven Treatment

RecruitingObservational study
  • The University of Chicago, Chicago
1 Day – 17 Years · All sexes · Updated Aug 14, 2026 · NCT06274788

Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia

RecruitingPhase 1/2
  • Research Site, Chicago
Ages 12 and older · All sexes · Updated Jul 13, 2026 · NCT07109219

Using Text Messages to Improve Oral Chemotherapy for Adolescents and Adults With Acute Lymphoblastic Leukemia

Recruiting
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 15 and older · All sexes · Updated Jul 10, 2026 · NCT06446661

A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs)

RecruitingObservational study
  • Northwestern Memorial Hospital, Chicago
  • Rush University Medical Center, Chicago
  • University of Illinois at Chicago, Chicago
  • and 2 more
All ages · All sexes · Updated Jul 6, 2026 · NCT01351545

Mobile Health Intervention to Support Oral Chemotherapy Adherence in Adolescents and Young Adults With Leukemia

Recruiting
  • Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago
Ages 14 and older · All sexes · Updated Jun 30, 2026 · NCT03932903

Ruxolitinib and Chemotherapy in Adolescents and Young Adults With Ph-like Acute Lymphoblastic Leukemia

RecruitingPhase 1
  • University of Chicago Medical Center, Chicago
Ages 18 to 39 · All sexes · Updated Jun 29, 2026 · NCT03571321

Study of Chemotherapy-Free Induction Regimen for Ph+ Acute Lymphoblastic Leukemia With Inotuzumab Ozogamicin (InO)

RecruitingPhase 2
  • University of Chicago Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jun 5, 2026 · NCT04747912

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

RecruitingObservational study
  • Lurie Children's Hospital-Chicago, Chicago
All ages · All sexes · Updated May 18, 2026 · NCT01790152

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

RecruitingPhase 1
  • University of Chicago, Chicago
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

RecruitingPhase 1/2
  • Northwestern, Chicago
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL)

RecruitingPhase 1/2
  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
Ages 18 and older · All sexes · Updated Mar 18, 2026 · NCT06207123

Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma

RecruitingPhase 2
  • University of Chicago Comprehensive Cancer Center, Chicago
Ages 18 to 54 · All sexes · Updated Mar 17, 2026 · NCT06918431

Venetoclax Basket Trial for High Risk Hematologic Malignancies

RecruitingPhase 1
  • Ann & Robert H Lurie Children's Hospital of Chicago, Chicago
Ages 1 to 40 · All sexes · Updated Mar 12, 2026 · NCT05292664

Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies

RecruitingPhase 1
  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
Ages 1 to 21 · All sexes · Updated Dec 6, 2024 · NCT05476770

Acute Lymphoblastic Leukemia trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.