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Amyotrophic Lateral Sclerosis clinical trials in St. Louis, MO

9 studies for Amyotrophic Lateral Sclerosis are looking for participants at sites in and around St. Louis (within about 30 miles). Open a study to see who can join and how to contact the study team.

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

RecruitingPhase 3
  • Washington University, St Louis
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07322003

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

Study of COYA 302 for the Treatment of ALS

RecruitingPhase 2/3
  • Washington University, St Louis
Ages 18 to 80 · All sexes · Updated Aug 6, 2026 · NCT07161999

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • Washinton University in St. Louis, St Louis
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

Tofersen in Non-SOD1 ALS

RecruitingPhase 2
  • Washington University ALS Center, St Louis
Ages 18 and older · All sexes · Updated Jun 25, 2026 · NCT07294144

ALS/MND Natural History Study Data Repository

RecruitingObservational study
  • Saint Louis University, St Louis
Ages 18 to 90 · All sexes · Updated May 20, 2026 · NCT05966038

Intermuscular Coherence as a Biomarker for ALS

RecruitingObservational studyHealthy volunteers welcome
  • Washington University Medical Center, St Louis
Ages 20 to 90 · All sexes · Updated Feb 9, 2026 · NCT05104710

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

RecruitingObservational studyHealthy volunteers welcome
  • Washington University, St Louis
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

About Amyotrophic Lateral Sclerosis

ALS stands for Amyotrophic Lateral Sclerosis, also called Lou Gehrig's disease. ALS affects the nervous system, causing muscle problems. Find out how.

More about Amyotrophic Lateral Sclerosis on MedlinePlus

Amyotrophic Lateral Sclerosis trials in other cities

Other studies in St. Louis

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.