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Amyotrophic Lateral Sclerosis clinical trials in Boston, MA
19 studies for Amyotrophic Lateral Sclerosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS
RecruitingPhase 1/2
- Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, Boston
Healey ALS MyMatch Common Screening Protocol
RecruitingObservational study
- Massachusetts General Hospital, Boston
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
RecruitingPhase 2
- Dana Farber Cancer Institute, Boston
ASSESS ALL ALS Study
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Brigham, Boston
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
RecruitingPhase 3
- Sean M. Healey & AMG Center for ALS, Boston
Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?
Recruiting
- Massachusetts General Hospital, Boston
ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
RAPA-501 Therapy for ALS
RecruitingPhase 2/3
- Massachusetts General Hospital, Boston
Controlling Amyotrophic Lateral Sclerosis Motor Neuron Excitability Study
Recruiting
- Beth Israel Deaconess Medical Center, Boston
Usnoflast Neuromuscular Investigation for Treatment Efficacy in Amyotrophic Lateral Sclerosis
RecruitingPhase 2
- Zydus US010, Boston
Tofersen in Non-SOD1 ALS
RecruitingPhase 2
- Massachusetts General Hospital, Boston
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Recruiting
- Massachusetts General Hospital, Boston
BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia
Recruiting
- Massachusetts General Hospital, Boston
EIM Via the Myolex mScan as an ALS Biomarker
RecruitingObservational study
- Massachusetts General Hospital, Boston
- Beth Israel Deaconess Medical Center, Boston
Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)
Recruiting
- Massachusetts General Hospital, Boston
AMX0114 in Adult Participants With Amyotrophic Lateral Sclerosis
RecruitingPhase 1
- Massachusetts General Hospital, Healey & AMG Center for ALS, Boston
A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Participants With Superoxide Dismutase 1 (SOD-1) Amyotrophic Lateral Sclerosis (ALS)
RecruitingObservational study
- Mass General Hospital -MGH, Boston
Intermuscular Coherence as a Biomarker for ALS
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
RecruitingObservational studyHealthy volunteers welcome
- Massachusetts General Hospital, Boston
About Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, is a nerve disease that weakens muscles and gets worse over time. Learn how to manage symptoms.
More about Amyotrophic Lateral Sclerosis on MedlinePlus
Amyotrophic Lateral Sclerosis trials in other cities
- Jacksonville, FL12 studies
- Philadelphia, PA12 studies
- Baltimore, MD11 studies
- San Diego, CA9 studies
- Chicago, IL9 studies
- San Francisco, CA8 studies
- New York City, NY8 studies
- St. Louis, MO8 studies
- Atlanta, GA7 studies
- Phoenix, AZ7 studies
- Houston, TX7 studies
- Miami, FL6 studies
Other studies in Boston
- Breast Cancer110 studies
- Cancer (all types)90 studies
- Non-Small Cell Lung Cancer87 studies
- Lung Cancer63 studies
- Colorectal Cancer62 studies
- Ovarian Cancer62 studies
- Metastatic Cancer61 studies
- Prostate Cancer56 studies
- Endometrial Cancer51 studies
- Depression50 studies
- Heart Failure46 studies
- Multiple Myeloma45 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.