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Amyotrophic Lateral Sclerosis clinical trials in Chicago, IL

10 studies for Amyotrophic Lateral Sclerosis are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS

RecruitingPhase 3
  • Northwestern University, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07322003

RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses

RecruitingPhase 2
  • Rush University Medical Center, Chicago
  • University of Chicago Medical Center, Chicago
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034

ASSESS ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University, Chicago
  • Synapticure (Remote Participation Only), Chicago
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06578195

PREVENT ALL ALS Study

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06581861

Study of COYA 302 for the Treatment of ALS

RecruitingPhase 2/3
  • Northwestern, Chicago
Ages 18 to 80 · All sexes · Updated Aug 6, 2026 · NCT07161999

ARTFL LEFFTDS Longitudinal Frontotemporal Lobar Degeneration (ALLFTD)

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04363684

Analysis of Human ALS Tissues and Registry of ALS Patients

RecruitingObservational study
  • University of Illinois at Chicago, Chicago
Ages 18 to 90 · All sexes · Updated Jul 8, 2026 · NCT05067179

ALS/MND Natural History Study Data Repository

RecruitingObservational study
  • Northwestern University, Chicago
Ages 18 to 90 · All sexes · Updated May 20, 2026 · NCT05966038

Clinical Outcome Assessment for AT & BCI

RecruitingHealthy volunteers welcome
  • Shirley Ryan AbilityLab, Chicago
Ages 18 and older · All sexes · Updated May 5, 2026 · NCT07407725

Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures

RecruitingObservational studyHealthy volunteers welcome
  • Northwestern University, Chicago
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05137665

About Amyotrophic Lateral Sclerosis

ALS stands for Amyotrophic Lateral Sclerosis, also called Lou Gehrig's disease. ALS affects the nervous system, causing muscle problems. Find out how.

More about Amyotrophic Lateral Sclerosis on MedlinePlus

Amyotrophic Lateral Sclerosis trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.