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Aortic Valve Stenosis clinical trials recruiting in the U.S.

36 studies for Aortic Valve Stenosis are recruiting participants at sites across the United States.

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Recently updated studies

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Recruiting
All ages · All sexes · Updated Sep 24, 2026 · NCT05172960

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

RecruitingObservational study
Ages 18 to 105 · All sexes · Updated Sep 24, 2026 · NCT06777368

CardioHeartConnect: Commercially Available Fitness for Cardiac Rehabilitation

Recruiting
Ages 18 and older · All sexes · Updated Sep 21, 2026 · NCT07008911

CAPTURE-2: Controlled Arterial Protection to Ultimately Remove Embolic Material

Recruiting
Ages 22 and older · All sexes · Updated Aug 26, 2026 · NCT07276711

Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR

RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Aug 21, 2026 · NCT05862558

Study of the Progression of Chronic Cardiovascular Conditions

RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07420907

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

RecruitingPhase 2/3
Ages 50 and older · All sexes · Updated Jul 6, 2026 · NCT07001800

Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia

RecruitingPhase 3
Ages 6 to 11 · All sexes · Updated May 15, 2026 · NCT06597019

Patient Quality of Recovery After TAVR With Different Sedation Regimens

RecruitingPhase 4
Ages 18 to 90 · All sexes · Updated Apr 29, 2026 · NCT07556523

DELINEATE-Prospective

RecruitingObservational study
Ages 18 and older · All sexes · Updated Apr 16, 2026 · NCT07197736

Detecting Changes in Arterial Blood Volume and Cardiac Efficiency

RecruitingObservational study
Ages 18 to 80 · All sexes · Updated Apr 13, 2026 · NCT07205341

STAR Trial (Siegel Transcatheter Aortic Valve Replacement in Patients With Symptomatic Severe Aortic Stenosis)

Recruiting
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT07278310

Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR

Recruiting
Ages 18 and older · All sexes · Updated Mar 24, 2026 · NCT05459233

AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction

RecruitingObservational study
Ages 60 and older · All sexes · Updated Mar 4, 2026 · NCT06580158

Comparative Imaging Assessment of Valvular Heart Disease

RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Jan 13, 2026 · NCT04126018

Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease

RecruitingObservational study
Ages 18 to 90 · All sexes · Updated Jan 2, 2026 · NCT06780241

Pre-Emptive LAVA-ECMO for Complex High-Risk TAVR

RecruitingObservational study
Ages 18 to 100 · All sexes · Updated Dec 30, 2025 · NCT07309029

Imaging Histone Deacetylase in the Heart

RecruitingHealthy volunteers welcome
Ages 18 to 85 · All sexes · Updated Dec 22, 2025 · NCT03549559

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

Recruiting
Ages 65 and older · All sexes · Updated Dec 17, 2025 · NCT04889872

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.