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Aortic Valve Stenosis clinical trials in Boston, MA

10 studies for Aortic Valve Stenosis are looking for participants at sites in and around Boston (within about 30 miles). Open a study to see who can join and how to contact the study team.

ALLIANCE: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve

Recruiting
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated Sep 24, 2026 · NCT05172960

REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE

RecruitingObservational study
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
Ages 18 to 105 · All sexes · Updated Sep 24, 2026 · NCT06777368

ALLIANCE AVIV: Safety and Effectiveness of the SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

Recruiting
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated Jul 27, 2026 · NCT05172973

Ataciguat for Slowing the Progression of Moderate Calcific Aortic Valve Stenosis: A Randomized, Placebo Controlled Study

RecruitingPhase 2/3
  • Massachusetts General Hospital, Boston
  • Brigham and Women's Hospital, Boston
Ages 50 and older · All sexes · Updated Jul 6, 2026 · NCT07001800

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

RecruitingPhase 2
  • Tufts Medical Center, Boston
  • Massachusetts General Hospital, Boston
  • Massachusetts General Hospital, Boston
  • and 2 more
Ages 50 to 80 · All sexes · Updated Jun 23, 2026 · NCT05646381

Imaging Histone Deacetylase in the Heart

RecruitingHealthy volunteers welcome
  • Massachusetts General Hospital, Boston
Ages 18 to 85 · All sexes · Updated Dec 22, 2025 · NCT03549559

PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR

Recruiting
  • Massachusetts General Hospital Boston, Boston
Ages 65 and older · All sexes · Updated Dec 17, 2025 · NCT04889872

Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement

Recruiting
  • Tufts Medical, Boston
  • Massachusetts General Hospital, Boston
All ages · All sexes · Updated Jul 24, 2025 · NCT04634240

PARTNER 3 Trial - Aortic Valve-in-Valve

Recruiting
  • Brigham and Women's Hospital, Boston
All ages · All sexes · Updated May 10, 2024 · NCT03003299

The HALT Biomarker Study

RecruitingPhase 1
  • Massachusetts General Hospital, Boston
Ages 65 and older · All sexes · Updated Nov 10, 2021 · NCT04552275

Aortic Valve Stenosis trials in other cities

Other studies in Boston

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.