🔎 Trials Near Me

Home › Colorectal Cancer › Texas › Dallas

Colorectal Cancer clinical trials in Dallas, TX

33 studies for Colorectal Cancer are looking for participants at sites in and around Dallas (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)

RecruitingPhase 1/2
  • UT Southwest Simmons Cancer Center, Dallas
Ages 12 and older · All sexes · Updated Oct 2, 2026 · NCT04585750

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #89, Dallas
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT05176483

Open-Label Study of BBO-10203 in Subjects With Advanced Solid Tumors

RecruitingPhase 1
  • SCRI at Mary Crowley, Dallas
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT06625775

A Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • GSK Investigational Site, Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07277270

Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors

RecruitingPhase 1
  • Research Site, Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06218914

A Study of Amivantamab and FOLFIRI Versus Cetuximab/Bevacizumab and FOLFIRI in Participants With KRAS/NRAS and BRAF Wild-type Colorectal Cancer Who Have Previously Received Chemotherapy

RecruitingPhase 3
  • Parkland Health and Hospital System, Dallas
  • Texas Oncology DFW, Dallas
  • UT Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06750094

Testing Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP Trial

RecruitingPhase 3
  • Parkland Memorial Hospital, Dallas
  • UT Southwestern Simmons Cancer Center - RedBird, Dallas
  • UT Southwestern/Simmons Cancer Center-Dallas, Dallas
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT05863195

Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis

RecruitingPhase 1/2
  • Baylor, Scott and White Research Institute, Dallas
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06047379

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

RecruitingPhase 1
  • Texas Oncology - DFW (Sammons CC), Dallas
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07114601

A Study of LY4337713 in Participants With FAP-Positive Solid Tumors

RecruitingPhase 1
  • Texas Oncology - DFW (Sammons CC), Dallas
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07213791

Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

RecruitingPhase 1
  • NEXT - Dallas, Dallas
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07349537

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Clinical Study Site, Dallas
  • Clinical Study Site, Dallas
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07228832

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)

RecruitingPhase 1/2
  • Texas Oncology, P.A., Dallas
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT06330064

A Study of ART0380 for the Treatment of Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • Mary Crowley Cancer Research, Dallas
  • Texas Oncology - Baylor Charles A. Sammons Cancer Center, Dallas
Ages 18 and older · All sexes · Updated Jul 30, 2026 · NCT04657068

A Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid Tumors

RecruitingPhase 1/2
  • Texas Oncology, Dallas
Ages 18 and older · All sexes · Updated Jul 29, 2026 · NCT03526835

A Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal Cancer

RecruitingPhase 3
  • Texas Oncology - DFW, Dallas
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT05253651

A Phase 2 Study of Zanidatamab in Patients With HER2-expressing Tumors

RecruitingPhase 2
  • Texas Oncology - DFW, Dallas
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06695845

A Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal Cancer

RecruitingPhase 4
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06562543

[18F]FPyQCP PET Imaging of Fibroblast Activation Protein in Selected Oncology Indications

RecruitingPhase 1/2
  • University of Texas Southwestern Medical Center, Dallas
Ages 18 to 80 · All sexes · Updated Jun 23, 2026 · NCT07432633

A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Texas LLC - Dallas, Dallas
Ages 18 to 99 · All sexes · Updated Jun 16, 2026 · NCT07540572

KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors

RecruitingPhase 1
  • UT Southwestern Simmons Cancer Center, Dallas
Ages 18 and older · All sexes · Updated Jun 8, 2026 · NCT06026410

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Sarah Cannon Research Institute at Mary Crowley, Dallas
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

BBO-11818 in Adult Subjects With KRAS Mutant Cancer

RecruitingPhase 1
  • Sarah Cannon Research Institute at Mary Crowley, Dallas
Ages 18 and older · All sexes · Updated Jun 2, 2026 · NCT06917079

Study of RMC-6236 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS

RecruitingPhase 1/2
  • Mary Crowley Cancer Research, Dallas
Ages 18 and older · All sexes · Updated May 15, 2026 · NCT05379985

Early-Onset Colorectal Cancer Patients Too Young for Screening

RecruitingObservational study
  • Methodist Dallas Medical Center- Clinical Research Institute, Dallas
Ages 35 and older · All sexes · Updated Apr 30, 2026 · NCT07559825

An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.

RecruitingPhase 2
  • NGM Clinical Study Site, Dallas
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT07033026

Study of CP-383 in Patients With Advanced or Metastatic Solid Tumors

RecruitingPhase 1/2
  • NEXT Oncology - Dallas, Dallas
Ages 18 and older · All sexes · Updated Feb 18, 2026 · NCT07030257

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

RecruitingPhase 1/2
  • NEXT Oncology Dallas, Dallas
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT07148128

Effect on Body Movement and Mental Skills in Patients Who Received Gadolinium-based Contrast Media for Magnetic Resonance Examination Multiple Times Within 5 Years

RecruitingPhase 4
  • UT Southwestern Medical Center, Dallas
Ages 18 to 64 · All sexes · Updated Jan 22, 2026 · NCT04373564

A Phase 1 Study of JMT108 in Participants With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Dallas, Dallas
Ages 18 and older · All sexes · Updated Jan 21, 2026 · NCT07317505

A First-in-human, Phase I, Open-label, Multicenter Study of NM1F(Anti-PVRIG) in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • NEXT Oncology, Dallas, Dallas
Ages 18 and older · All sexes · Updated Jan 26, 2024 · NCT05746897

About Colorectal Cancer

Colorectal cancer starts in the colon or rectum. It may not cause symptoms at first. Screening tests can help find it early, when treatment is most effective.

More about Colorectal Cancer on MedlinePlus

Colorectal Cancer trials in other cities

Other studies in Dallas

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.