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Colon Cancer clinical trials in North Carolina
20 studies for Colon Cancer are looking for participants at sites in North Carolina.
Cities in North Carolina
- Durham12 studies
- Charlotte5 studies
- Cary4 studies
- Winston-Salem3 studies
- Raleigh3 studies
- Goldsboro3 studies
- Jacksonville3 studies
A Study of PHN-012 in Patients With Advanced Solid Tumors
- PHN-012-001 Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)
- WakeMed Raleigh Campus ( Site 0094), Raleigh
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06997497Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer
- Duke Cancer Center Cary, Cary
- Duke Cancer Center - Investigational Chemotherapy Service, Durham
- Duke Cancer Center, Durham
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer
- Messino Cancer Center, Asheville
- The University of North Carolina At Chapel Hill, Chapel Hill
- Oncology Specialists of Charlotte, Charlotte
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation
- UNC- Chapel Hill, Chapel Hill
RecruitingObservational study
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444A Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)
- First Health of the Carolinas, Pinehurst
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07058012Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment Delays
- FirstHealth of the Carolinas-Moore Regional Hospital, Pinehurst
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07283939Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps
- Southeastern Medical Oncology Center-Clinton, Clinton
- Southeastern Medical Oncology Center-Goldsboro, Goldsboro
- Southeastern Medical Oncology Center-Jacksonville, Jacksonville
Recruiting
Ages 45 to 70 · All sexes · Updated Sep 2, 2026 · NCT05080673Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease
- Duke Cancer Center Cary, Cary
- UNC Health Cancer Care Cary, Cary
- Waverly Hematology Oncology, Cary
- and 22 more
RecruitingPhase 2/3
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169Family Communications After Genetic Testing
- Southeastern Medical Oncology Center-Clinton, Clinton
- CaroMont Regional Medical Center, Gastonia
- Southeastern Medical Oncology Center-Goldsboro, Goldsboro
- and 2 more
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT07143487Shield Post-Approval Study Protocol
- Cary Gastroenterology Associates, Cary
- University of North Carolina at Chapel Hill, Chapel Hill
- University of North Carolina at Chapel Hill, Chapel Hill
- and 1 more
RecruitingObservational studyHealthy volunteers welcome
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055Distance-Based Exercise to Preserve Function and Prevent Disability
- Novant Health Cancer Institute - Kernersville, Kernersville
- Novant Health Cancer Institute - Mount Airy, Mount Airy
- Novant Health Forsyth Medical Center, Winston-Salem
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07059884Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma
- Xencor Investigative Site, Charlotte
- Xencor Investigative Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142Integrated Cancer Repository for Cancer Research
- Cape Fear Valley Health System, Fayetteville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations
- Research Site, Durham
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors
- Duke Cancer Center, Durham
- Carolina BioOncology Institute, Huntersville
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
- GSK Investigational Site, Durham
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT05855200SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
- Massive Bio SYNERGY-AI site, Chapel Hill
- Massive Bio SYNERGY-AI site, Winston-Salem
RecruitingObservational study
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774Pilot Study for Colorectal Cancer and Advanced Adenoma Detection With the Mainz Biomed Colorectal Cancer Test
- Virtual Research Group, Morrisville
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Aug 12, 2025 · NCT06864338APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors
- University of North Carolina, Chapel Hill
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.