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Colon Cancer clinical trials in Durham, NC

12 studies for Colon Cancer are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study of PHN-012 in Patients With Advanced Solid Tumors

RecruitingPhase 1
  • PHN-012-001 Site, Durham
Ages 18 and older · All sexes · Updated Sep 29, 2026 · NCT07127874

Symbiotic-GI-03: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Adult Participants With Metastatic Colorectal Cancer

RecruitingPhase 3
  • Duke Cancer Center - Investigational Chemotherapy Service, Durham
  • Duke Cancer Center, Durham
  • Duke University Hospital - Vascular Interventional Radiology, Durham
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07222800

A Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal Cancer

RecruitingPhase 3
  • The University of North Carolina At Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT07284849

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • UNC- Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

Colon Adjuvant Chemotherapy Based on Evaluation of Residual Disease

RecruitingPhase 2/3
  • Duke University Medical Center, Durham
  • UNC Lineberger Comprehensive Cancer Center, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT05174169

Shield Post-Approval Study Protocol

RecruitingObservational studyHealthy volunteers welcome
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
  • University of North Carolina at Chapel Hill, Hillsborough · 13 mi away
Ages 45 to 81 · All sexes · Updated Aug 7, 2026 · NCT06880055

Study of XmAb®819 in Subjects With Advanced Clear Cell Renal Cell Carcinoma

RecruitingPhase 1
  • Xencor Investigative Site, Durham
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT05433142

A Study to Learn About Study Medicine ALTA3263 in Adults With Advanced Solid Tumors With KRAS Mutations

RecruitingPhase 1
  • Research Site, Durham
Ages 18 and older · All sexes · Updated Jun 10, 2026 · NCT06835569

Study of RMC-9805 in Participants With KRAS G12D-Mutant Solid Tumors

RecruitingPhase 1
  • Duke Cancer Center, Durham
Ages 18 and older · All sexes · Updated Jun 3, 2026 · NCT06040541

Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer

RecruitingPhase 3
  • GSK Investigational Site, Durham
Ages 18 and older · All sexes · Updated Jan 23, 2026 · NCT05855200

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Chapel Hill · 10 mi away
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors

RecruitingPhase 2
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Jun 27, 2025 · NCT03175224

Colon Cancer trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.