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COPD clinical trials in Houston, TX

18 studies for COPD are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

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A Study to Investigate the Efficacy and Safety of GSK5784283 (Felcorekibart) Compared With Placebo in Participants With Moderate to Very Severe COPD (PERSIST COPD-1)

RecruitingPhase 3
  • GSK Investigational Site, Humble · 17 mi away
Ages 40 to 80 · All sexes · Updated Nov 12, 2026 · NCT07780669

A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

RecruitingPhase 2
  • Baylor College of Medicine Medical Center, Houston
Ages 40 to 75 · All sexes · Updated Nov 5, 2026 · NCT07759245

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

RecruitingPhase 2
  • Research Site, Houston
Ages 40 and older · All sexes · Updated Oct 23, 2026 · NCT07082738

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype

RecruitingPhase 3
  • Se Houston- Site Number : 8400120, Houston
  • Aavon Clinical Trials, Llc- Site Number : 8400166, Houston
Ages 40 to 80 · All sexes · Updated Oct 23, 2026 · NCT07190222

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

RecruitingPhase 2/3
  • Greater Heights & Memorial Pulmonary and Sleep, Houston
  • Houston Pulmonary Sleep and Allergy Associates, Houston
Ages 35 to 80 · All sexes · Updated Oct 22, 2026 · NCT07363694

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Recruiting
  • Houston Methodist/Primary Critical Care, Houston
Ages 40 to 84 · All sexes · Updated Oct 19, 2026 · NCT06891755

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

RecruitingPhase 3
  • Trio Clinical Trials- Site Number : 8400106, Houston
  • HDH Research, Inc.- Site Number : 8400104, Houston
  • Baylor College of Medicine- Site Number : 8400076, Houston
  • and 2 more
Ages 40 to 80 · All sexes · Updated Oct 19, 2026 · NCT07190209

STRIVE Post-Market Registry Study

RecruitingObservational study
  • University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT04302272

The Study of Chronic Obstructive Pulmonary Disease (COPD) Participants Treated With Dupilumab (STRIDE) Registry

RecruitingObservational study
  • The Respire Institute, Houston
Ages 40 and older · All sexes · Updated Oct 15, 2026 · NCT07612878

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)

RecruitingPhase 3
  • Research Site, Houston
  • Research Site, Houston
  • Research Site, Houston
Ages 40 to 80 · All sexes · Updated Oct 9, 2026 · NCT06878261

Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

RecruitingPhase 3
  • GSK Investigational Site, Houston
Ages 40 to 80 · All sexes · Updated Oct 5, 2026 · NCT06961214

Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation

RecruitingPhase 3
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
Ages 40 to 80 · All sexes · Updated Oct 5, 2026 · NCT06959095

A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease

RecruitingPhase 3
  • Research Site, Houston
  • Research Site, Houston
  • Research Site, Houston
Ages 40 to 80 · All sexes · Updated Oct 2, 2026 · NCT06283966

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07059091

A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)

RecruitingPhase 3
  • Research Site, Houston
  • Research Site, Houston
  • Research Site, Humble · 17 mi away
Ages 40 to 80 · All sexes · Updated Sep 3, 2026 · NCT06883305

eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation

RecruitingPhase 3
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
  • GSK Investigational Site, Houston
Ages 40 to 75 · All sexes · Updated Jul 28, 2026 · NCT07177339

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

RecruitingObservational study
  • Horizon Clinical Research Group, Houston
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Recruiting
  • Respire Research Institute, Houston
Ages 30 and older · All sexes · Updated Feb 6, 2025 · NCT05204888

About COPD

COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. At first symptoms are mild, but they usually become more severe. Learn more.

More about COPD on MedlinePlus

COPD trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.