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COPD clinical trials in Chicago, IL

14 studies for COPD are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype

RecruitingPhase 3
  • University of Illinois-Chicago - College of Medicine- Site Number : 8400055, Chicago
Ages 40 to 80 · All sexes · Updated Sep 22, 2026 · NCT07190209

An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema

Recruiting
  • Northwestern University, Chicago
  • University of Chicago Medical Center, Chicago
Ages 40 to 80 · All sexes · Updated Sep 17, 2026 · NCT06035120

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

RecruitingPhase 2
  • Northwestern University, Chicago
  • Rush University Medical Center, Chicago
Ages 40 and older · All sexes · Updated Sep 4, 2026 · NCT07059091

STRIVE Post-Market Registry Study

RecruitingObservational study
  • Northwestern University, Division of Pulmonary and Critical Care Medicine, Chicago
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT04302272

Functional Improvement in OSA and COPD With a Telehealth LifeStyle and Exercise Intervention

Recruiting
  • Jesse Brown VA Medical Center, Chicago
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT06390345

SPIROMICS Study of Early COPD Progression (SOURCE)

RecruitingObservational studyHealthy volunteers welcome
  • University of Illinois Chicago, Chicago
Ages 30 to 55 · All sexes · Updated Jun 3, 2026 · NCT05033990

A Multi Center Study Testing a New Implant for Adults With Severe Emphysema

Recruiting
  • Northwestern University, Chicago
Ages 22 and older · All sexes · Updated Jun 3, 2026 · NCT07119229

Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3

Recruiting
  • University of Chicago, Chicago
Ages 40 to 84 · All sexes · Updated Apr 24, 2026 · NCT06891755

Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)

RecruitingPhase 3
  • GSK Investigational Site, Chicago
Ages 40 to 80 · All sexes · Updated Apr 9, 2026 · NCT06961214

PiMZ Longitudinal Cohort (PiMZ Logic)

RecruitingObservational study
  • University of Chicago, Chicago
Ages 18 and older · All sexes · Updated Jan 16, 2026 · NCT06505603

COPD Resources, Education, and Activity Designed for You Study

Recruiting
  • Rush University Medical Center, Chicago
Ages 40 and older · All sexes · Updated Sep 22, 2025 · NCT07125053

Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening

RecruitingObservational study
  • University of Chicago, Chicago
Ages 50 and older · All sexes · Updated Aug 5, 2025 · NCT06122077

myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

Recruiting
  • University of Chicago, Chicago
Ages 30 and older · All sexes · Updated Feb 6, 2025 · NCT05204888

About COPD

COPD (chronic obstructive pulmonary disease) makes it hard for you to breathe. At first symptoms are mild, but they usually become more severe. Learn more.

More about COPD on MedlinePlus

COPD trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.