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Crohn's Disease clinical trials in Chicago, IL

9 studies for Crohn's Disease are looking for participants at sites in and around Chicago (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

RecruitingPhase 3
  • University of Chicago Medical Center ( Site 5066), Chicago
Ages 16 to 80 · All sexes · Updated Sep 29, 2026 · NCT06430801

Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease

RecruitingPhase 2
  • University of Chicago Medical Center /ID# 267400, Chicago
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT06548542

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

RecruitingPhase 3
  • Rush University Medical Center, Chicago
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Rush University Medical Center-Site Number: 8400015, Chicago
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Master Protocol (IIBD): A Study of Multiple Drugs in Adults With Ulcerative Colitis or Crohn's Disease

RecruitingPhase 2
  • Rush University Medical Center, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483073

A Study of LY4395089 and Mirikizumab (LY3074828) Given Together and Mirikizumab (Alone) in Adults With Crohn's Disease

RecruitingPhase 2
  • Rush University Medical Center, Chicago
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT07483099

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

RecruitingPhase 4
  • University of Chicago Medicine, Chicago
Ages 18 to 70 · All sexes · Updated Sep 9, 2026 · NCT06045754

Treat-to-Target of Endoscopic Remission in Patients With IBD in Symptomatic Remission

Recruiting
  • University of Chicago Medicine, Chicago
Ages 18 and older · All sexes · Updated Aug 7, 2026 · NCT05230173

Treatment of Moderate to Severe Refractory Crohn's Disease

RecruitingPhase 1/2
  • Northwestern, Chicago
  • University of Chicago, Chicago
Ages 18 to 65 · All sexes · Updated Dec 10, 2025 · NCT06721962

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Chicago

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.