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Crohn's Disease clinical trials in Durham, NC

12 studies for Crohn's Disease are looking for participants at sites in and around Durham (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

RecruitingPhase 3
  • University of North Carolina Medical Center ( Site 5034), Chapel Hill · 10 mi away
Ages 16 to 80 · All sexes · Updated Oct 2, 2026 · NCT06430801

A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07499232

A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 2/3
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07196722

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Duke University Medical Center-Site Number: 8400093, Durham
  • UNC Hospitals, The University of North Carolina at Chapel Hill-Site Number: 8400074, Chapel Hill · 10 mi away
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184931

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • UNC Hospitals, The University of North Carolina at Chapel Hill-Site Number: 8400074, Chapel Hill · 10 mi away
Ages 16 to 80 · All sexes · Updated Sep 23, 2026 · NCT07184944

A Study to Assess Concentration of TREMFYA in Breast Milk of Lactating Women Who Are Receiving TREMFYA Therapeutically

RecruitingPhase 4
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 and older · Women · Updated Aug 28, 2026 · NCT07654751

A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • University of North Carolina Hospital, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT07577843

Zymfentra (Infliximab-dyyb) REal World Cohort STudy

RecruitingObservational study
  • University of North Carolina, Chapel Hill · 10 mi away
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07237516

Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD)

Recruiting
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 18 to 44 · Women · Updated Jul 14, 2026 · NCT07337902

Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease

RecruitingPhase 3
  • Univ NC Chapel Hill /ID# 262198, Chapel Hill · 10 mi away
Ages 2 to 17 · All sexes · Updated Jun 24, 2026 · NCT06332534

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

RecruitingObservational study
  • Duke Health System, Durham
  • University of North Carolina at Chapel Hill, Chapel Hill · 10 mi away
Ages 1 to 18 · All sexes · Updated Apr 17, 2026 · NCT07198113

A Study to Investigate Efficacy and Safety of SAR442970 in Patients With Crohn's Disease

RecruitingPhase 2
  • Investigational Site Number: 8400003, Chapel Hill · 10 mi away
Ages 18 to 75 · All sexes · Updated Mar 27, 2026 · NCT06958536

About Crohn's Disease

Crohn's Disease can cause inflammation in any area from the mouth to the anus. Read about medicines, surgery or dietary management to treat symptoms.

More about Crohn's Disease on MedlinePlus

Crohn's Disease trials in other cities

Other studies in Durham

From ClinicalTrials.gov, data retrieved Oct 5, 2026. Each study sets its own eligibility; the study team decides who can join.