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Depression clinical trials in Missouri
20 studies for Depression are looking for participants at sites in Missouri.
Cities in Missouri
Lumateperone for Late-Life Depression
- Washington University School of Medicine, St Louis
RecruitingPhase 3
Ages 60 and older · All sexes · Updated Sep 16, 2026 · NCT07623135A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
- Seaport Investigator Site, St Louis
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07065240Efficacy of a Multi-level School Intervention for LGBTQ Youth
- Washington University in St. Louis, St Louis
RecruitingHealthy volunteers welcome
Ages 12 to 20 · All sexes · Updated Sep 11, 2026 · NCT05541406A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
- Psychiatric Care and Research Center, O'Fallon
- St. Charles Psychiatric Associates - Midwest Research Group, Saint Charles
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407Regulating Together for Prader-Willi Syndrome: A Group Behavioral Therapy for Emotion Dysregulation
- Children's Mercy, Kansas City
Recruiting
Ages 13 to 17 · All sexes · Updated Sep 2, 2026 · NCT07607730Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) Stage II
- Washington University School of Medicine/Barnes-Jewish Hospital, St Louis
RecruitingPhase 2
Ages 60 and older · All sexes · Updated Aug 27, 2026 · NCT06867549Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
- St. Louis VA Medical Center John Cochran Division, St. Louis, MO, St Louis
Recruiting
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT06162741Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older
- Washington University School of Medicine in St Louis, St Louis
Recruiting
Ages 50 to 74 · All sexes · Updated Aug 18, 2026 · NCT06636058A Study of Brenipatide in Adult Participants With Major Depressive Disorder
- Arch Clinical Trials, St Louis
RecruitingPhase 3
Ages 18 to 75 · All sexes · Updated Aug 6, 2026 · NCT07412756E-Mindfulness Approaches for Living After Breast Cancer
- Lake Regional Hospital, Osage Beach
- Heartland Regional Medical Center, Saint Joseph
- Mercy Hospital Springfield, Springfield
- and 2 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
- Tekton Research, St Louis
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, O'Fallon
- Neurocrine Clinical Site, Saint Charles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401Leveraging mHealth to Promote Opioid Use Recovery and Mental Health Among Residents of a Medium-Sized Midwestern City
- Washington University School of Medicine, St Louis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Jun 29, 2026 · NCT07673380A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- University of Missouri, Columbia
- Psychiatric Care and Research, O'Fallon
- Washington University School of Medicine, St Louis
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715Depression and Driving
- Washington University School of Medicine, St Louis
RecruitingObservational study
Ages 65 and older · All sexes · Updated Jun 8, 2026 · NCT05446805Clinical Trial on Agitation in Alzheimer's Dementia
- Tekton Research LLC, St Louis
RecruitingPhase 2
Ages 60 and older · All sexes · Updated May 20, 2026 · NCT05543681A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- Midwest Research Group, Saint Charles
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830Just-In-Time Adaptive Interventions (JITAIs) in a Digital Mental Health Intervention for Middle-Aged and Older Adults With Chronic Pain
- Washington University in St. Louis School of Medicine, St Louis
Recruiting
Ages 45 and older · All sexes · Updated May 5, 2026 · NCT06978166INCLUDE Program: A Perioperative Wellness Program Tailored for Black Surgical Patients
- Washington University School of Medicine, St Louis
Recruiting
Ages 60 and older · All sexes · Updated Mar 25, 2026 · NCT07283783A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
- Clinical Research Site, Saint Charles
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.