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Depression clinical trials in North Carolina
26 studies for Depression are looking for participants at sites in North Carolina.
Cities in North Carolina
Brexanolone Lifting Outcomes Of Moms
- Lipocine Investigational Site, Chapel Hill
RecruitingPhase 3
Ages 15 to 45 · Women · Updated Sep 16, 2026 · NCT07822321RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
- Magnolia Clinical Research, Llc, Cary
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407Project neuroARTEMIS
- Wake Forest University School of Medicine, Winston-Salem
Recruiting
Ages 18 to 59 · All sexes · Updated Sep 3, 2026 · NCT06814275Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 5 to 99 · All sexes · Updated Sep 3, 2026 · NCT06587230Neuroscience of Psychotherapy for Depression
- Carolina Center for Neurostimulation, Chapel Hill
Recruiting
Ages 18 to 30 · All sexes · Updated Aug 27, 2026 · NCT06696001NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Charlotte
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06963021E-Mindfulness Approaches for Living After Breast Cancer
- Atrium Health Stanly/LCI-Albemarle, Albemarle
- Cone Health MedCenter Asheboro, Asheboro
- Cone Health Cancer Center at Alamance Regional, Burlington
- and 16 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
- New Hope Clinical Research, Charlotte
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379Telehealth Music Therapy for Adults With Endocrine Disorder and Depression
- Appalachian State University, Boone
Recruiting
Ages 18 to 65 · All sexes · Updated Jul 30, 2026 · NCT07413874Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
- Duke University Medical Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06538246CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
- Womack Army Medical Center, Fort Bragg
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05663034A New Intervention to Improve Function in Veterans With Anxiety and Depression
- Durham VA Medical Center, Durham, NC, Durham
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Jul 7, 2026 · NCT06188923TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
- University of North Carolina School of Medicine, Chapel Hill
RecruitingObservational study
18 Months – 11 Years · All sexes · Updated Jul 6, 2026 · NCT07048574Enhancing Slow Wave Sleep in Depression
- Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 40 to 80 · All sexes · Updated Jun 29, 2026 · NCT07143838CARED : A Novel Rapid Treatment Paradigm for Depression
- Carolina Center for Neurostimulation, Chapel Hill
Recruiting
Ages 18 to 70 · All sexes · Updated Jun 25, 2026 · NCT07507370Identifying and Treating Depression in the Orthopaedic Trauma Population
- Wake Forest University Health Sciences, Winston-Salem
RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05976347Examining the Effects of Estradiol on Neural and Molecular Response to Reward
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 4
Ages 45 to 55 · Women · Updated Apr 29, 2026 · NCT05282277SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Immigrant Families
- Duke School of Nursing, Durham
RecruitingHealthy volunteers welcome
Ages 12 to 100 · All sexes · Updated Apr 9, 2026 · NCT06627764Adolescent Mood During Puberty and Testosterone
- Carolina Crossing B, Suite 1, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 11 to 14 · All sexes · Updated Jan 14, 2026 · NCT06072677Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit
- East Carolina University, Greenville
- Wake Forest University, Winston-Salem
Recruiting
Ages 15 to 39 · All sexes · Updated Jan 7, 2026 · NCT07173205Depression, Aging, Stress and Heart Health Study
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 44 to 55 · Women · Updated Dec 22, 2025 · NCT05570721Supporting Health in Veterans With Heart Failure
- VA Clinic - Durham, Durham
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Nov 13, 2025 · NCT05839067Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression
- University of North Carolina, Chapel Hill, Chapel Hill
RecruitingPhase 4
Ages 18 to 45 · Women · Updated Oct 29, 2025 · NCT06610305Comparing Cognitive-Behavioral Therapy Versus Mindfulness-Based Therapy for Autistic Adults
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 and older · All sexes · Updated Sep 18, 2025 · NCT06060860A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
- Clinical Research Site, Hickory
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.