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Depression clinical trials in North Carolina
23 studies for Depression are looking for participants at sites in North Carolina.
Cities in North Carolina
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Nov 10, 2026 · NCT07002034E-Mindfulness Approaches for Living After Breast Cancer
- Atrium Health Stanly/LCI-Albemarle, Albemarle
- Cone Health MedCenter Asheboro, Asheboro
- Cone Health Cancer Center at Alamance Regional, Burlington
- and 16 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
- University of North Carolina School of Medicine, Chapel Hill
RecruitingObservational study
18 Months – 11 Years · All sexes · Updated Nov 3, 2026 · NCT07048574Single Session Personalized Aperiodic Transcranial Alternating Current Stimulation (PandA-tACS) for Antenatal Depression
- Carolina Center for Neurostimulation, Department of Psychiatry, UNC-Chapel Hill, Chapel Hill
Recruiting
Ages 18 to 45 · Women · Updated Nov 3, 2026 · NCT07799480SER Familia: A Family-Based Intervention Addressing Syndemic Conditions Among Latino Families
- Duke School of Nursing, Durham
RecruitingHealthy volunteers welcome
Ages 12 to 100 · All sexes · Updated Oct 16, 2026 · NCT06627764A New Intervention to Improve Function in Veterans With Anxiety and Depression
- Durham VA Medical Center, Durham, NC, Durham
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Oct 14, 2026 · NCT06188923Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder
- Qortical Clinical Partners, Durham
Recruiting
Ages 22 and older · All sexes · Updated Oct 8, 2026 · NCT07282678Brexanolone Lifting Outcomes Of Moms
- Lipocine Investigational Site, Chapel Hill
RecruitingPhase 3
Ages 15 to 45 · Women · Updated Sep 16, 2026 · NCT07822321Teachers Leading the Front Lines - North Carolina (Tealeaf-NC)
- University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 5 to 99 · All sexes · Updated Sep 3, 2026 · NCT06587230Project neuroARTEMIS
- Wake Forest University School of Medicine, Winston-Salem
Recruiting
Ages 18 to 59 · All sexes · Updated Sep 3, 2026 · NCT06814275Neuroscience of Psychotherapy for Depression
- Carolina Center for Neurostimulation, Chapel Hill
Recruiting
Ages 18 to 30 · All sexes · Updated Aug 27, 2026 · NCT06696001NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Charlotte
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 10, 2026 · NCT06963021Telehealth Music Therapy for Adults With Endocrine Disorder and Depression
- Appalachian State University, Boone
Recruiting
Ages 18 to 65 · All sexes · Updated Jul 30, 2026 · NCT07413874Adaptive Coping Skills Training to Improve Psychological Distress Among Cardiorespiratory Failure Survivors
- Duke University Medical Center, Durham
Recruiting
Ages 18 and older · All sexes · Updated Jul 23, 2026 · NCT06538246CBT-I vs. MBTI for Traumatic Brain Injury (TBI)-Related Insomnia and Post-Traumatic Stress Symptoms
- Womack Army Medical Center, Fort Bragg
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05663034Enhancing Slow Wave Sleep in Depression
- Wake Forest University Health Sciences, Winston-Salem
Recruiting
Ages 40 to 80 · All sexes · Updated Jun 29, 2026 · NCT07143838CARED : A Novel Rapid Treatment Paradigm for Depression
- Carolina Center for Neurostimulation, Chapel Hill
Recruiting
Ages 18 to 70 · All sexes · Updated Jun 25, 2026 · NCT07507370Identifying and Treating Depression in the Orthopaedic Trauma Population
- Wake Forest University Health Sciences, Winston-Salem
RecruitingPhase 4
Ages 18 and older · All sexes · Updated May 22, 2026 · NCT05976347Examining the Effects of Estradiol on Neural and Molecular Response to Reward
- University of North Carolina at Chapel Hill, Chapel Hill
RecruitingPhase 4
Ages 45 to 55 · Women · Updated Apr 29, 2026 · NCT05282277Adolescent Mood During Puberty and Testosterone
- Carolina Crossing B, Suite 1, Chapel Hill
RecruitingHealthy volunteers welcome
Ages 11 to 14 · All sexes · Updated Jan 14, 2026 · NCT06072677Optimizing the AYA Survivors' Coping and Emotional Needs Toolkit
- East Carolina University, Greenville
- Wake Forest University, Winston-Salem
Recruiting
Ages 15 to 39 · All sexes · Updated Jan 7, 2026 · NCT07173205Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression
- University of North Carolina, Chapel Hill, Chapel Hill
RecruitingPhase 4
Ages 18 to 45 · Women · Updated Oct 29, 2025 · NCT06610305A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
- Clinical Research Site, Hickory
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.