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Depression clinical trials in Ohio
26 studies for Depression are looking for participants at sites in Ohio.
Cities in Ohio
RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Cleveland Clinic, Cleveland
- The Ohio State University, Department of Psychiatry, Columbus
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
- Seaport Investigator Site, Independence
- Seaport Investigator Site, North Canton
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated Sep 14, 2026 · NCT07065240A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder (X-NOVA3)
- Insight Clinical Trials, Independence
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Sep 8, 2026 · NCT07076407A Study to Evaluate the Effectiveness of DT-101 as an Adjunctive Treatment in Patients With Depression
- Draig Clinical Site, Columbus
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07610473NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Mason
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112E-Mindfulness Approaches for Living After Breast Cancer
- Indu and Raj Soin Medical Center, Beavercreek
- University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
- Ohio State University Comprehensive Cancer Center, Columbus
- and 16 more
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
- Neuro-Behavioral Clinical Research, North Canton
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains
- Lindner Center of Hope, Mason
RecruitingPhase 1/2
Ages 18 to 60 · All sexes · Updated Aug 3, 2026 · NCT06795451Developing Resilience and Anxiety Management Through the Arts
- Case Western Reserve University, Cleveland
Recruiting
Ages 8 to 17 · All sexes · Updated Jul 31, 2026 · NCT07033052A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
- Cleveland Clinic - Cleveland /ID# 276309, Cleveland
- CincyScience /ID# 226318, West Chester
RecruitingPhase 3
Ages 10 to 17 · All sexes · Updated Jul 27, 2026 · NCT04777357Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Avon Lake
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06966401A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and Anxiety
- The Ohio State University Department of Psychiatry, Columbus
RecruitingPhase 2
Ages 21 to 65 · All sexes · Updated Jul 23, 2026 · NCT06820723Virtual Poetry Workshops to Enhance Patient Well Being and Reduce Anxiety
- Ohio State University Wexner Medical Center, Columbus
Recruiting
Ages 18 and older · All sexes · Updated Jul 21, 2026 · NCT07717541TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age
- Cincinnati Children's Hospital Medical Center, Cincinnati
RecruitingObservational study
18 Months – 11 Years · All sexes · Updated Jul 6, 2026 · NCT07048574A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- The Ohio State University, Columbus
- Charak Center for Health and Wellness, Garfield Heights
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715Teenthrive 2: Treatments for Improving Mood in Teens
- Nationwide Children's Hospital, Columbus
Recruiting
Ages 12 to 18 · All sexes · Updated Jun 10, 2026 · NCT07475845Psilocybin-Assisted Therapy for the Treatment of Major Depressive Disorder in Patients With Non-Small Cell Lung Cancer
- Ohio State University Comprehensive Cancer Center, Columbus
RecruitingPhase 2
Ages 18 and older · All sexes · Updated May 14, 2026 · NCT07216404A Precision Medicine Approach to Target Engagement for Emotion Regulation
- Ohio State University, Columbus
Recruiting
Ages 18 and older · All sexes · Updated May 11, 2026 · NCT05651295A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)
- The Ohio State University, Columbus
- Neuro Behavioral Clinical Research, Inc., North Canton
RecruitingPhase 2
Ages 18 to 65 · All sexes · Updated May 11, 2026 · NCT06524830Virtual Patient Groups for Sarcoidosis Associated Fatigue
- Cleveland Clinic, Cleveland
Recruiting
Ages 18 and older · All sexes · Updated Apr 24, 2026 · NCT07073963Positive Processes and Transition to Health - Single-Session (PATH-SS)
- Case Western Reserve University, Cleveland
RecruitingMentions payment for participants
Ages 18 to 65 · All sexes · Updated Apr 22, 2026 · NCT06900712Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth
- University of Cincinnati, Department of Psychiatry and Behavioral Neuroscience, Cincinnati
RecruitingPhase 3
Ages 15 to 24 · All sexes · Updated Mar 11, 2026 · NCT07464886Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus
- Cincinnati Children's Hospital Medical Center, Cincinnati
Recruiting
Ages 12 to 22 · All sexes · Updated Oct 30, 2025 · NCT06232304Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
- Neurocrine Clinical Site, Avon Lake
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Oct 29, 2025 · NCT06786624Mechanisms of Rumination Change in Adolescent Depression
- Nationwide Children's Hospital, Columbus
- The Ohio State University, Columbus
Recruiting
Ages 14 to 17 · All sexes · Updated Aug 11, 2025 · NCT03859297A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
- Clinical Research Site, Cincinnati
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.