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Depression clinical trials in Cincinnati, OH

8 studies for Depression are looking for participants at sites in and around Cincinnati (within about 30 miles). Open a study to see who can join and how to contact the study team.

NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

RecruitingPhase 3
  • Neurocrine Clinical Site, Mason · 19 mi away
Ages 18 and older · All sexes · Updated Aug 11, 2026 · NCT06911112

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • University of Cincinnati Cancer Center-UC Medical Center, Cincinnati
  • University of Cincinnati Cancer Center-West Chester, West Chester · 15 mi away
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222

Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic Domains

RecruitingPhase 1/2
  • Lindner Center of Hope, Mason · 19 mi away
Ages 18 to 60 · All sexes · Updated Aug 3, 2026 · NCT06795451

TIDES 2.0: Prevalence and Longitudinal Course of Depression, Anxiety, and Behavior Problems in Children With Cystic Fibrosis Under 12 Years of Age

RecruitingObservational study
  • Cincinnati Children's Hospital Medical Center, Cincinnati
18 Months – 11 Years · All sexes · Updated Jul 6, 2026 · NCT07048574

Prefrontal Glutamatergic Modulation by NAC and MBCT for Depression in Youth

RecruitingPhase 3
  • University of Cincinnati, Department of Psychiatry and Behavioral Neuroscience, Cincinnati
Ages 15 to 24 · All sexes · Updated Mar 11, 2026 · NCT07464886

Transforming Care for Individuals With Childhood-onset Systemic Lupus Erythematosus

Recruiting
  • Cincinnati Children's Hospital Medical Center, Cincinnati
Ages 12 to 22 · All sexes · Updated Oct 30, 2025 · NCT06232304

A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

RecruitingPhase 4
  • Clinical Research Site, Cincinnati
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Cincinnati

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.