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Depression clinical trials in Tennessee
12 studies for Depression are looking for participants at sites in Tennessee.
Cities in Tennessee
A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)
- Clinical Neuroscience Solutions Inc. - Memphis, Mephis
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07621237RE104 Safety and Efficacy Study in Adjustment Disorder in Cancer and Other Medical Illnesses
- Alliance for Multispecialty Research Clinical, Knoxville
RecruitingPhase 2
Ages 18 to 80 · All sexes · Updated Sep 15, 2026 · NCT07002034PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study
- Athena Care, Nashville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06713616AI-Based Personalized Exercise Prescription Through Mobile Health on Physical Activity and Health Outcomes in Older Adults: A Feasibility Study
- Kinesiology, Recreation, and Sport Studies (865) 974-3340 [email protected], Knoxville
RecruitingHealthy volunteers welcome
Ages 65 and older · All sexes · Updated Aug 20, 2026 · NCT07768670E-Mindfulness Approaches for Living After Breast Cancer
- University of Tennessee - Knoxville, Knoxville
- Baptist Memorial Hospital and Cancer Center-Memphis, Memphis
- Vanderbilt Breast Center at One Hundred Oaks, Nashville
RecruitingPhase 3
Ages 18 to 50 · All sexes · Updated Aug 4, 2026 · NCT06748222A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder
- Clinical Neuroscience Solutions, Inc., Memphis
RecruitingPhase 3
Ages 18 to 74 · All sexes · Updated Aug 3, 2026 · NCT06775379A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression
- Neuroscience and TMS Treatment Center, Brentwood
Recruiting
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT03887715Neural Correlates of Psychiatric Disorders
- Vanderbilt University Medical Center, Nashville
RecruitingObservational study
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT04725409Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
- University of Tennessee Medical Center, Knoxville
- University of Tennessee Health Science Center/Regional One Health, Memphis
Recruiting
Ages 18 and older · All sexes · Updated Jan 29, 2026 · NCT06374277Latino Teen Depression Treatment Study
- Researchmatch.org, Nashville
RecruitingObservational studyHealthy volunteers welcome
Ages 13 and older · All sexes · Updated Jan 15, 2026 · NCT05499182CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth
- Judy Garber, Nashville
Recruiting
Ages 13 to 17 · All sexes · Updated Sep 9, 2025 · NCT05456035A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
- Clinical Research Site, Memphis
RecruitingPhase 4
Ages 18 to 65 · All sexes · Updated Jan 23, 2025 · NCT06223880From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.