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Depression clinical trials in Nashville, TN

8 studies for Depression are looking for participants at sites in and around Nashville (within about 30 miles). Open a study to see who can join and how to contact the study team.

Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →

E-Mindfulness Approaches for Living After Breast Cancer

RecruitingPhase 3
  • Vanderbilt Breast Center at One Hundred Oaks, Nashville
Ages 18 to 50 · All sexes · Updated Nov 4, 2026 · NCT06748222

To Improve Depressive Symptoms Using a Web-App

Recruiting
  • Vanderbilt University, Nashville
Ages 40 to 60 · Women · Updated Oct 30, 2026 · NCT05405803

Cancer Pain Management Using a Web-based Intervention

Recruiting
  • Vanderbilt University, Nashville
Ages 18 and older · Women · Updated Oct 30, 2026 · NCT06085313

CBT Enhanced With Social Cognitive Training vs. CBT Only With Depressed Youth

Recruiting
  • Judy Garber, Nashville
Ages 13 to 17 · All sexes · Updated Oct 23, 2026 · NCT05456035

PCORI Comparative Effectiveness Study-Esketamine (Spravato) vs. Ketamine-Equivalence Study

RecruitingPhase 3
  • Athena Care, Nashville
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT06713616

Neural Correlates of Psychiatric Disorders

RecruitingObservational study
  • Vanderbilt University Medical Center, Nashville
Ages 18 and older · All sexes · Updated Jun 12, 2026 · NCT04725409

Latino Teen Depression Treatment Study

RecruitingObservational studyHealthy volunteers welcome
  • Researchmatch.org, Nashville
Ages 13 and older · All sexes · Updated Jan 15, 2026 · NCT05499182

About Depression

Depression is a serious medical illness. It affects almost 7 percent of U.S. adults. It causes feelings of sadness, hopelessness, and frustration that do not go away. Learn about treatments.

More about Depression on MedlinePlus

Depression trials in other cities

Other studies in Nashville

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.