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Epilepsy clinical trials in Houston, TX

16 studies for Epilepsy are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Diagnosing Epilepsy To EffeCT Change

Recruiting
  • University of Texas Health Science Center at Houston, Houston
Ages 18 to 75 · All sexes · Updated Sep 15, 2026 · NCT07110337

Prospective Natural History Study of POLG Disease

RecruitingObservational study
  • UTHealth Houston, Houston
All ages · All sexes · Updated Sep 15, 2026 · NCT07775872

Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures

RecruitingPhase 3
  • Baylor College of Medicine, Houston
  • University of Texas Health Science Center in Houston, Houston
Ages 18 to 75 · All sexes · Updated Sep 2, 2026 · NCT07594119

Subcortical Arousal in Perceptual Awareness

Recruiting
  • Baylor College of Medicine, Houston
Ages 13 and older · All sexes · Updated Aug 10, 2026 · NCT06934356

A Study to Evaluate XEN1101 as Adjunctive Therapy in Primary Generalized Tonic-Clonic Seizures

RecruitingPhase 3
  • UTHealth Science Center at Houston, Houston
Ages 12 and older · All sexes · Updated Aug 10, 2026 · NCT05667142

The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project

RecruitingPhase 4
  • The University of Texas Health Science Center at Houston, Houston
Ages 16 and older · All sexes · Updated Jul 15, 2026 · NCT07112365

Mapping of Human Cognition

Recruiting
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 to 75 · All sexes · Updated Jul 14, 2026 · NCT05989893

Understanding Prefrontal and Medial Temporal Neuronal Responses to Algorithmic Cognitive Variables in Epilepsy Patients

Recruiting
  • Baylor College of Medicine, Houston
Ages 10 to 64 · All sexes · Updated Jul 6, 2026 · NCT05283811

Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))

RecruitingPhase 3
  • UTHealth Houston, Houston
Ages 18 to 75 · All sexes · Updated Jun 9, 2026 · NCT05135091

An Examination of Whether Infrared Light Therapy Can Reduce Stress in People With Epilepsy

Recruiting
  • Houston Neuroscience Brain Center, Houston
Ages 18 and older · All sexes · Updated Apr 23, 2026 · NCT07509177

Intracranial Investigation of Neural Circuity Underlying Human Mood

Recruiting
  • Baylor College of Medicine, Houston
Ages 21 to 70 · All sexes · Updated Mar 4, 2026 · NCT05871372

A Long-term Study of the Safety and Effectiveness of RAP-219 in Adults With Focal Onset Seizures

RecruitingPhase 2
  • Baylor College of Medicine, Houston
Ages 18 to 70 · All sexes · Updated Jan 23, 2026 · NCT07219407

Stopping TSC Onset and Progression 2B: Sirolimus TSC Epilepsy Prevention Study

RecruitingPhase 2
  • University of Texas HSC at Houston, Houston
1 Day – 6 Months · All sexes · Updated Jan 22, 2026 · NCT05104983

Managing Agitated Delirium With Neuroleptics and Anti-Epileptics as a Neuroleptic Sparing Strategy

RecruitingPhase 2/3Healthy volunteers welcome
  • MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Nov 18, 2025 · NCT05431595

Mapping and Modulating the Spatiotemporal Dynamics of Socio-Affective Processing

RecruitingHealthy volunteers welcome
  • Baylor College of Medicine, Houston
Ages 22 to 70 · All sexes · Updated Oct 27, 2025 · NCT05418894

Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder

RecruitingHealthy volunteers welcome
  • Michael E. DeBakey VA Medical Center, Houston
  • The University of Texas health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Jan 9, 2025 · NCT06695767

About Epilepsy

Epilepsy is a brain disorder that causes people to have seizures. The seizures may be mild or severe. Learn about causes, diagnosis, and treatment.

More about Epilepsy on MedlinePlus

Epilepsy trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.