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Head and Neck Squamous Cell Carcinoma clinical trials in Baltimore, MD

15 studies for Head and Neck Squamous Cell Carcinoma are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.

A Study of Amivantamab in Addition to Standard of Care Agents (SOC) Compared With SOC Alone in Participants With Recurrent/Metastatic Head and Neck Cancer

RecruitingPhase 3
  • University of Maryland Greenebaum Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07276399

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

RecruitingPhase 1/2
  • University of Maryland School of Medicine, Baltimore
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06385080

Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma

RecruitingPhase 2
  • University of Maryland/Greenebaum Cancer Center, Baltimore
  • UM Baltimore Washington Medical Center/Tate Cancer Center, Glen Burnie · 9 mi away
Ages 18 to 79 · All sexes · Updated Sep 22, 2026 · NCT04671667

Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment

RecruitingPhase 3
  • University of Maryland/Greenebaum Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06589804

Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery

RecruitingPhase 2
  • Greater Baltimore Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT02734537

Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors

RecruitingPhase 2
  • Research Site, Baltimore
Ages 18 and older · All sexes · Updated Sep 11, 2026 · NCT06535607

A Longitudinal Multi-Omic Biomarker Profiling Study of Patients With Head & Neck Squamous Cell Carcinoma (HNSCC)

RecruitingObservational study
  • University of Maryland, Baltimore
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT06163534

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

RecruitingPhase 2
  • Greater Baltimore Medical Center, Baltimore
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT06532279

Study of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid Tumors

RecruitingPhase 1
  • Exelixis Clinical Site #14, Baltimore
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT05176483

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

RecruitingPhase 2/3
  • Site #0112, Baltimore
Ages 18 and older · All sexes · Updated Jul 17, 2026 · NCT06788990

Study With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic Tumors

RecruitingPhase 1
  • Johns Hopkins Hospital /ID# 254056, Baltimore
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT04777994

A Study of Ficlatuzumab in Combination With Cetuximab in Participants With Recurrent or Metastatic (R/M) HPV Negative Head and Neck Squamous Cell Carcinoma

RecruitingPhase 3
  • University of Maryland, Baltimore
Ages 18 and older · All sexes · Updated Apr 9, 2026 · NCT06064877

A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation

RecruitingPhase 1
  • Johns Hopkins - Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Feb 13, 2026 · NCT06778863

Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)

RecruitingPhase 2
  • Maryland Proton Treatment Center, Baltimore
  • University of Maryland Greenebaum Cancer Center, Baltimore
  • Baltimore Washington Medical Center, Glen Burnie · 9 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Nov 10, 2025 · NCT06088381

A Phase I/II Study of VLS-1488 in Subjects With Advanced Cancer

RecruitingPhase 1/2
  • Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore
Ages 18 and older · All sexes · Updated Nov 4, 2025 · NCT05902988

Head and Neck Squamous Cell Carcinoma trials in other cities

Other studies in Baltimore

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.