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Breast Cancer clinical trials in Baltimore, MD
44 studies for Breast Cancer are looking for participants at sites in and around Baltimore (within about 30 miles). Open a study to see who can join and how to contact the study team.
Recruiting for a study here? Feature it at the top of this page — $99 for 30 days →
Evaluation of Lasofoxifene Combined With Abemaciclib Compared With Fulvestrant Combined With Abemaciclib in Locally Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation
RecruitingPhase 3
- Johns Hopkins Kimmel Cancer Center, Baltimore
S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity
RecruitingPhase 3
- UM Upper Chesapeake Medical Center, Bel Air · 22 mi away
A Clinical Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) in People With Breast Cancer (MK-2870-032)
RecruitingPhase 3
- Mercy Medical Center - Baltimore ( Site 0015), Baltimore
Phase 3 Study of RLY-2608 + Fulvestrant vs Capivasertib + Fulvestrant as Treatment for Locally Advanced or Metastatic PIK3CA-mutant HR+/HER2- Breast Cancer
RecruitingPhase 3
- Sidney Kimmel Comprehensive Cancer Center (SKCCC) at Johns Hopkins, Baltimore
A Study Evaluating the Efficacy and Safety of Inavolisib Plus CDK4/6 Inhibitor and Letrozole vs Placebo + CDK4/6i and Letrozole in Participants With Endocrine-Sensitive PIK3CA-Mutated, Hormone Receptor-Positive, HER2-Negative Advanced Breast Cancer
RecruitingPhase 3
- University of Maryland, Baltimore
- Velocity Clinical Research, Annapolis · 22 mi away
E-Mindfulness Approaches for Living After Breast Cancer
RecruitingPhase 3
- Maryland Proton Treatment Center, Baltimore
- University of Maryland/Greenebaum Cancer Center, Baltimore
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
- and 7 more
Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection
RecruitingObservational studyHealthy volunteers welcome
- Mercy Medical Center, Baltimore
- Sinai Hospital of Baltimore, Baltimore
- MedStar Franklin Square Medical Center/Weinberg Cancer Institute, Baltimore
- and 2 more
Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics
RecruitingObservational study
- University of Maryland/Greenebaum Cancer Center, Baltimore
- Sinai Hospital of Baltimore, Baltimore
- UM Saint Joseph Medical Center, Towson · 8 mi away
- and 1 more
A Study of LY4337713 in Participants With FAP-Positive Solid Tumors
RecruitingPhase 1
- United Theranostics, Glen Burnie · 9 mi away
Evaluating the Addition of Adjuvant Chemotherapy to Ovarian Function Suppression Plus Endocrine Therapy in Premenopausal Patients With pN0-1, ER-Positive/HER2-Negative Breast Cancer and an Oncotype Recurrence Score Less Than or Equal to 25
RecruitingPhase 3
- University of Maryland/Greenebaum Cancer Center, Baltimore
- Mercy Medical Center, Baltimore
- Greater Baltimore Medical Center, Baltimore
- and 8 more
ROSETTA Breast-01: The Effects and Safety of Pumitamig in Patients With Triple-Negative Breast Cancer
RecruitingPhase 3
- Saint Agnes Hospital, Clinical Research Center, Baltimore
EXActDNA-003 / NSABP B-64: Study of Molecular Residual Disease Detection in Breast Cancer (MRD)
RecruitingObservational study
- Weinberg Center at Mercy, Baltimore
- Greater Baltimore Medical Center, Baltimore
- Sinai Hospital of Baltimore, Baltimore
- and 3 more
Prospective Evaluation Of High-Dose Systemic Methotrexate In Patients With Breast Cancer And Leptomeningeal Metastasis
RecruitingPhase 2
- Sidney Kimmel Comprehensive Cancer Center, Baltimore
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
RecruitingPhase 2
- Johns Hopkins University, Baltimore
A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer
RecruitingPhase 1/2
- Maryland Oncology Hematology - Annapolis, Annapolis · 22 mi away
The Cancer of the Pancreas Screening-5 CAPS5)Study
RecruitingPhase 3
- Johns Hopkins Hospital, Baltimore
A Study to Learn About the Study Medicine Called PF-07248144 in Combination With Fulvestrant in People With HR-positive, HER2-negative Advanced or Metastatic Breast Cancer Who Progressed After a Prior Line of Treatment.
RecruitingPhase 3
- Mercy Medical Center - Baltimore, Baltimore
- Mfsmc-Hjwci, Baltimore
- MedStar Franklin Square Cancer Center at Loch Raven, Baltimore
- and 1 more
A Study of Sacituzumab Tirumotecan (MK-2870) as a Single Agent and in Combination With Pembrolizumab (MK-3475) Versus Treatment of Physician's Choice in Participants With HR+/HER2- Unresectable Locally Advanced or Metastatic Breast Cancer (MK-2870-010)
RecruitingPhase 3
- Greenebaum Comprehensive Cancer Center ( Site 0036), Baltimore
A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies
RecruitingPhase 1/2
- Research Site, Baltimore
Phase 1 Study of CLR 125 in Triple Negative Breast Cancer
RecruitingPhase 1
- United Theranostics, Glen Burnie · 9 mi away
Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer
RecruitingPhase 2
- Maryland Proton Treatment Center, Baltimore
Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy
RecruitingPhase 3
- Maryland Proton Treatment Center, Baltimore
Palazestrant in Combination With Ribociclib for the First-line Treatment of ER+/HER2- Advanced Breast Cancer
RecruitingPhase 3
- Clinical Trial Site, Baltimore
- Clinical Trial Site, Baltimore
- Clinical Trial Site, Annapolis · 22 mi away
Evolutionary Clinical Trial for Novel Biomarker-Driven Therapies
RecruitingPhase 2
- Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
PET Dynamics to Response-Adapted Neoadjuvant Therapy in TNBC
RecruitingPhase 2
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
Cardiometabolic Screening Program
Recruiting
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
A Pivotal Phase II Clinical Trial of Utidelone Injection Plus Capecitabine in HER2-negative Breast Cancer Patients With Brain Metastases
RecruitingPhase 2
- The Johns Hopkins Sidney Kimmel Cancer Center, Johns Hopkins School of Medicine, Baltimore
Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial
RecruitingPhase 3
- Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore
A Study of Izalontamab Brengitecan Versus Chemotherapy in Participants With Previously Untreated, Locally Advanced, Recurrent Inoperable, or Metastatic Triple-negative Breast Cancer Ineligible for Anti-PD(L)1 Drugs (IZABRIGHT-Breast01)
RecruitingPhase 2/3
- Local Institution - 1035, Baltimore
Phase 3 Study to Evaluate the Efficacy and Safety of HER2/Neu Peptide GLSI-100 (GP2 + GM-CSF) in HER2/Neu Positive Subjects
RecruitingPhase 3
- Maryland Oncology Hematology, Annapolis · 22 mi away
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
RecruitingPhase 2
- The John Hopkins Hospital, Baltimore
EXoPERT EMERALD Clinical Study
RecruitingObservational studyHealthy volunteers welcome
- John Hopkins University, Baltimore
CD40 Agonist, Flt3 Ligand, and Chemotherapy in HER2 Negative Breast Cancer
RecruitingPhase 1
- Johns Hopkins University, Baltimore
Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors
RecruitingPhase 1
- Advanced Molecular Imaging and Therapy, Glen Burnie · 9 mi away
- United Theranostics - Chesapeake, Glen Burnie · 9 mi away
De-Escalation of Breast Radiation Trial for Hormone Sensitive, HER-2 Negative, Oncotype Recurrence Score Less Than or Equal to 18 Breast Cancer (DEBRA)
RecruitingPhase 3
- University of Maryland/Greenebaum Cancer Center, Baltimore
- Greater Baltimore Medical Center, Baltimore
- Saint Agnes Hospital, Baltimore
- and 7 more
The Effects of Treating Insomnia on Behavioral Weight Loss Outcomes in Survivors of Breast Cancer
Recruiting
- Sidney Kimmel Comprehensive Cancer Center, the Avon Foundation Breast Center at Johns Hopkins, Baltimore
- Johns Hopkins Bayview, Baltimore
- Johns Hopkins Kimmel Cancer Center at Greenspring Station, Lutherville · 9 mi away
GammaPod Dose Escalation Radiation for Early Stage Breast Cancer
Recruiting
- UMMC, Baltimore
- Baltimore Washington Medical Center, Glen Burnie · 9 mi away
- Upper Chesapeake Health, Bel Air · 22 mi away
A Study of CLSP-1025 in Adult Patients With Solid Tumors That Harbor the p53 R175H Mutation
RecruitingPhase 1
- Johns Hopkins - Sidney Kimmel Comprehensive Cancer Center, Baltimore
Metabotyping of Broccoli Microgreen in Obese Breast Cancer Survivors
Recruiting
- Breast Evaluation and Treatment Program, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore
Study in Patients With Breast Cancer Leptomeningeal Metastasis
RecruitingObservational study
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
RecruitingObservational study
- Massive Bio SYNERGY-AI site, Baltimore
- Massive Bio SYNERGY-AI site, Towson · 8 mi away
MammaPrint, BluePrint, and Full-genome Data Linked With Clinical Data to Evaluate New Gene EXpression Profiles
RecruitingObservational study
- Mercy Medical Center, Baltimore
- Johns Hopkins Hospital, Baltimore
- Luminis Health Center for Cancer & Blood Disorders, Annapolis · 22 mi away
A Trial of AMXI-5001 for Treatment in Patients With Advanced Malignancies
RecruitingPhase 1/2
- Johns Hopkins, Baltimore
First in Human Phase 1 Study of AG01 Anti-Progranulin/GP88 Antibody in Advanced Solid Tumor Malignancies
RecruitingPhase 1
- University of Maryland Greenebaum Comprehensive Cancer Center, Baltimore
About Breast Cancer
Breast cancer is a cancer that starts in the breast tissue, when cells change and grow out of control. Learn about the types, diagnosis, and treatments.
More about Breast Cancer on MedlinePlus
Breast Cancer trials in other cities
- New York City, NY144 studies
- Houston, TX126 studies
- Boston, MA110 studies
- Nashville, TN78 studies
- Los Angeles, CA73 studies
- Edison, NJ70 studies
- Queens, NY67 studies
- Durham, NC63 studies
- St. Louis, MO63 studies
- Chicago, IL59 studies
- Dallas, TX54 studies
- Philadelphia, PA51 studies
Other studies in Baltimore
- Non-Small Cell Lung Cancer60 studies
- Prostate Cancer45 studies
- Lung Cancer41 studies
- Cancer (all types)36 studies
- Colorectal Cancer30 studies
- Pancreatic Cancer30 studies
- Metastatic Cancer26 studies
- Obesity24 studies
- Bladder Cancer24 studies
- Ovarian Cancer23 studies
- Heart Failure23 studies
- Stroke20 studies
From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.