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Heart Failure clinical trials in California
65 studies for Heart Failure are looking for participants at sites in California.
Cities in California
- San Francisco29 studies
- San Diego23 studies
- Los Angeles20 studies
- Mountain View14 studies
- Sacramento12 studies
- Santa Monica11 studies
- Santa Clarita7 studies
- Chula Vista6 studies
- West Covina6 studies
- San Bernardino5 studies
- Pomona5 studies
- Huntington Beach5 studies
- Torrance5 studies
- Orange5 studies
- Santa Maria4 studies
- Simi Valley4 studies
- Burbank4 studies
- Vista4 studies
- Concord4 studies
- Thousand Oaks3 studies
- Long Beach3 studies
- Pasadena3 studies
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
- University of California Davis, Sacramento
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Beverly Hills
- Research Site, Huntington Beach
- Research Site, Huntington Park
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- National Heart Institute, Beverly Hills
- UC San Diego Health - Sulpizio Cardiovascular Center, La Jolla
- Nutrition Research Center (SPH), Loma Linda
- and 10 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
- Keck Medicine of USC-Norris Healthcare Center - Transplant Clinic, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Valley Clinical Trials, Inc., Covina
- North Coast Cardiology, Encinitas
- Merced Vein and Vascular Center, Merced
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06935370A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Velocity Clinical Research-Chula Vista, Chula Vista
- University of California Irvine, Orange
- North America Research Institute, San Dimas
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288Alleviant ALLAY-HFrEF Study
- Keck Medical Center of USC, Los Angeles
- University California Los Angeles Medical Center, Los Angeles
- UC Davis Medical Center, Sacramento
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT06812533Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- National Heart Institute, Beverly Hills
- Valley Clinical Trials, LLC dba Flourish Research, Covina
- National Institute of Clinical Research, Huntington Beach
- and 9 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Huntington Beach
- Research Site, Inglewood
- Research Site, La Jolla
- and 10 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Sep 15, 2026 · NCT06677060Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Beverly Hills
- Research Site, Covina
- Research Site, Los Angeles
- and 6 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Sep 11, 2026 · NCT06307652A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Chula Vista, CA Investigative Site 10111, Chula Vista
- Huntington Beach, CA Investigative Site 10031, Huntington Beach
- Los Angeles, CA Investigative Site 10089, Los Angeles
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- Chula Vista, CA Investigative Site CON-10111, Chula Vista
- CON-10075 El Centro, CA Investigational Site, El Centro
- CON-10024 Sacramento, CA Investigational Site, Sacramento
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746Investigation of the BrioVAD System for the Treatment of Left Ventricular Heart Failure
- Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 to 100 · All sexes · Updated Sep 9, 2026 · NCT06310031Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Scripps Memorial Hospital, La Jolla
- Cedars Sinai Medical Center, Los Angeles
- Alta Bates Summit Medical Center, Oakland
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07069738Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure
- University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT03586336A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 162, Beverly Hills
- Local Institution - 120, San Diego
- Local Institution - 149, Vista
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Aug 31, 2026 · NCT07795814Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 0002), Los Angeles
- Lucile Packard Children's Hospital ( Site 0040), Palo Alto
- Loma Linda University Health System ( Site 0008), San Bernardino
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Aug 28, 2026 · NCT05714085AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- BioSolutions Clinical Research Center, Imperial
- Profound Research LLC, Pasadena
- University of California, San Francisco - Heart and Vascular Center, San Francisco
- and 2 more
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436NORM-HF Pivotal Study
- Cardiovascular Institute of San Diego, Chula Vista
- UC Davis, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07574593Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- John Muir Health, Concord
- Zuckerberg San Francisco General, San Francisco
- University of California San Francisco, San Francisco
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Lucile Packard Children's Hospital, Palo Alto
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- La Jolla
- Salinas
- Stanford
- and 2 more
RecruitingObservational study
All ages · All sexes · Updated Aug 20, 2026 · NCT00271180LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
- Tenax Investigational Site, Sacramento
- Tenax Investigational Site, San Francisco
- Tenax Investigational Site, Stanford
- and 1 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Aug 19, 2026 · NCT07288398A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Keck School of Medicine of USC-Usc, Los Angeles
- Stanford Health Care Hospital & Clinics, Palo Alto
- University Of California San Francisco Medical Center, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- InvivoCure -2, Alhambra
- Cardio Research of S. Cal, Beverly Hills
- Westside Medical Associates Los Angeles, Beverly Hills
- and 30 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Memorial Care Long Beach Medical Center, Long Beach
- UC Davis Medical Center, Sacramento
- Scripps Clinical Research Services, San Diego
- and 2 more
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- VA Long Beach Healthcare System, Long Beach, CA, Long Beach
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
Recruiting
Ages 60 and older · All sexes · Updated Aug 14, 2026 · NCT05996328OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Cedars-Sinai Medical Center, Los Angeles
- Stanford University, Palo Alto
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System
- Lucile Packard Children's Hospital, Palo Alto
RecruitingPhase 2
Ages 0 to 16 · All sexes · Updated Aug 10, 2026 · NCT06080074Assessment of CCM in HF With Higher Ejection Fraction
- John Muir Health, Concord
- University of California San Diego, La Jolla
- USC Keck School of Medicine, Los Angeles
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Aug 6, 2026 · NCT05064709A Trial of CRD-4730 in HFrEF
- Cardurion Investigative Site, Pasadena
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Aug 6, 2026 · NCT07750873A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Valley Clinical Trials, Covina
- UCSD NAFLD Research Center, La Jolla
- Valley Clinical Trials, Northridge
- and 3 more
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Aug 5, 2026 · NCT06979362Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
- Division of Research, Pleasanton
Recruiting
Ages 18 and older · All sexes · Updated Aug 5, 2026 · NCT07467668ELEVATE-HFpEF Clinical Study
- Sutter Health Hospital, San Francisco
Recruiting
Ages 40 and older · All sexes · Updated Aug 3, 2026 · NCT06678841Staged Kidney Transplantation During Combined Heart/Kidney Transplantation
- Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Jul 24, 2026 · NCT06877169Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
- UC San Francisco Medical Center, San Francisco
RecruitingPhase 3
Ages 2 to 11 · All sexes · Updated Jul 24, 2026 · NCT06597006Implementation and Interaction of Clinician And Patient-facing Tools Aiming to Intensify Neurohormonal Medicines for Heart Failure
- Sutter Health, Walnut Creek
Recruiting
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT06526988A Study to Evaluate Finerenone on Clinical Efficacy and Safety in Patients With Heart Failure Who Are Intolerant or Not Eligible for Treatment With Steroidal Mineralocorticoid Receptor Antagonists
- Chula Vista, CA Investigative Site FIN-10419, Chula Vista
- Chula Vista, CA Investigative Site FIN-10111, Chula Vista
- FIN-10407, Northridge, CA, Northridge
- and 12 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jul 10, 2026 · NCT06033950The STOP-MED CTRCD Trial
- University of California, Los Angeles, Los Angeles
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Jul 7, 2026 · NCT06183437From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.