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Heart Failure clinical trials in California
66 studies for Heart Failure are looking for participants at sites in California.
Cities in California
- San Francisco29 studies
- San Diego22 studies
- Los Angeles20 studies
- Mountain View14 studies
- Sacramento12 studies
- Santa Monica10 studies
- Santa Clarita7 studies
- West Covina6 studies
- Chula Vista6 studies
- Huntington Beach5 studies
- Burbank5 studies
- Orange5 studies
- Pomona5 studies
- Torrance4 studies
- San Bernardino4 studies
- Vista4 studies
- Simi Valley4 studies
- Santa Maria4 studies
- Concord4 studies
- Long Beach3 studies
- Thousand Oaks3 studies
- Pasadena3 studies
Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)
- The Regents of the University of California - Los Angeles (UCLA Pediatrics) ( Site 0002), Los Angeles
- Lucile Packard Children's Hospital ( Site 0040), Palo Alto
- Loma Linda University Health System ( Site 0008), San Bernardino
RecruitingPhase 2/3
29 Days – 17 Years · All sexes · Updated Nov 13, 2026 · NCT05714085A Study to Evaluate the Safety and Efficacy of AC01 Compared to Placebo in Participants With Chronic Heart Failure
- Progressive MD, InvivoCure, Van Nuys
RecruitingPhase 2
Ages 18 to 85 · All sexes · Updated Nov 12, 2026 · NCT07584967A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure
- Velocity Clinical Research-Chula Vista, Chula Vista
- University of California Irvine, Orange
- North America Research Institute, San Dimas
- and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06424288A Study to Test Whether Vicadrostat (BI 690517) in Combination With Empagliflozin Helps People With Heart Failure and a Weak Pumping Function of the Left Side of the Heart
- Valley Clinical Trials, Inc., Covina
- North Coast Cardiology, Encinitas
- Merced Vein and Vascular Center, Merced
- and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT06935370INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery
- Sutter Medical Center Sacramento, Sacramento
- California Pacific Medical Center, San Francisco
Recruiting
Ages 18 to 80 · All sexes · Updated Nov 12, 2026 · NCT06965504Left vs Left Randomized Clinical Trial
- University of California San Diego, La Jolla
Recruiting
Ages 18 and older · All sexes · Updated Nov 12, 2026 · NCT05650658Barostim-Enabled NEurohormonal Intervention For Improving Treatment of Heart Failure
- PIH Health Good Samaritan Hospital, Los Angeles
- Keck School of Medicine of USC, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Nov 9, 2026 · NCT07232030Trial to Evaluate Safety And Effectiveness of Mechanical Circulatory Support in Patients With Advancing Heart Failure
- Sutter Medical Center, Sacramento
- University of California at San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Nov 5, 2026 · NCT06526195Product Performance Report: Evaluate Long-term Reliability & Performance of Medtronic Marketed Cardiac Therapy Products
- La Jolla
- Salinas
- Stanford
- and 2 more
RecruitingObservational study
All ages · All sexes · Updated Nov 4, 2026 · NCT00271180Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
- National Heart Institute, Beverly Hills
- UC San Diego Health - Sulpizio Cardiovascular Center, La Jolla
- Nutrition Research Center (SPH), Loma Linda
- and 10 more
RecruitingPhase 3
Ages 18 to 85 · All sexes · Updated Nov 4, 2026 · NCT06736574Evaluating a Digital Aid to Improve ICD Decisions
- University of California, San Francisco, San Francisco
Recruiting
Ages 60 and older · All sexes · Updated Nov 3, 2026 · NCT07913204Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
- Scripps Memorial Hospital, La Jolla
- Cedars Sinai Medical Center, Los Angeles
- Alta Bates Summit Medical Center, Oakland
- and 3 more
Recruiting
Ages 18 and older · All sexes · Updated Nov 3, 2026 · NCT07069738ELEVATE-HFpEF Clinical Study
- Stanford University, Palo Alto
- Sutter Health Hospital, San Francisco
Recruiting
Ages 40 and older · All sexes · Updated Nov 3, 2026 · NCT06678841Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity
- National Heart Institute, Beverly Hills
- Valley Clinical Trials, LLC dba Flourish Research, Covina
- National Institute of Clinical Research, Huntington Beach
- and 9 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Oct 29, 2026 · NCT07037459A Study to Learn About the Study Medicine Called PF-07328948 in Adults With Heart Failure (BRANCH-HF)
- Comprehensive Cardiovascular Care, Santa Maria
- FOMAT Medical Research, Santa Maria
RecruitingPhase 2
Ages 18 to 79 · All sexes · Updated Oct 23, 2026 · NCT06991257Assessment of CCM in HF With Higher Ejection Fraction
- University of California San Diego, La Jolla
- USC Keck School of Medicine, Los Angeles
- Cedars Sinai Medical Center, Los Angeles
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 23, 2026 · NCT05064709Sensor-based Congestion ALert for Events in Peritoneal Dialysis (SCALE-PD)
- Desert Cities Dialysis, Victorville
RecruitingObservational study
Ages 21 and older · All sexes · Updated Oct 22, 2026 · NCT07059962Phase III Study Investigating Heart Failure and Cardiovascular Death With Baxdrostat in Combination With Dapagliflozin
- Research Site, Concord
- Research Site, Daly City
- Research Site, Huntington Beach
- and 12 more
RecruitingPhase 3
Ages 40 and older · All sexes · Updated Oct 21, 2026 · NCT06677060NORM-HF Pivotal Study
- Cardiovascular Institute of San Diego, Chula Vista
- UC Davis, Sacramento
Recruiting
Ages 18 and older · All sexes · Updated Oct 16, 2026 · NCT07574593A Study of EDG-15400 in Adults With Heart Failure With Preserved Ejection Fraction (EQUINOX-HFpEF)
- Local Institution - 2, Beverly Hills
- Local Institution - 3, San Diego
- Local Institution - 4, Vista
RecruitingPhase 2
Ages 30 to 84 · All sexes · Updated Oct 13, 2026 · NCT07795814Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
- Research Site, Beverly Hills
- Research Site, Covina
- Research Site, Los Angeles
- and 6 more
RecruitingPhase 3
Ages 18 to 130 · All sexes · Updated Oct 13, 2026 · NCT06307652CSP #2025 - Geriatric OUt-of-hospital Randomized MEal Trial in Heart Failure: Veterans Affairs (GOURMET-VA)
- VA Long Beach Healthcare System, Long Beach, CA, Long Beach
- VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
- VA Greater Los Angeles Healthcare System, West Los Angeles, CA, West Los Angeles
Recruiting
Ages 60 and older · All sexes · Updated Oct 7, 2026 · NCT05996328Alleviant ALLAY-HFrEF Study
- Keck Medical Center of USC, Los Angeles
- University California Los Angeles Medical Center, Los Angeles
- UC Davis Medical Center, Sacramento
- and 2 more
Recruiting
Ages 18 and older · All sexes · Updated Oct 6, 2026 · NCT06812533A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy
- Valley Clinical Trials, Covina
- UCSD NAFLD Research Center, La Jolla
- Valley Clinical Trials, Northridge
- and 3 more
RecruitingPhase 2
Ages 40 to 84 · All sexes · Updated Oct 5, 2026 · NCT06979362Infusing Needed Iron to Target Insufficiency in Adults Treated for Evidence of Heart Failure
- Division of Research, Pleasanton
Recruiting
Ages 18 and older · All sexes · Updated Oct 1, 2026 · NCT07467668A Phase 1 AAV Gene Therapy Trial Evaluating Safety and Preliminary Efficacy of RP-A701 in Subjects With BAG3 Dilated Cardiomyopathy
- University of California, San Diego, San Diego
RecruitingPhase 1
Ages 18 to 65 · All sexes · Updated Oct 1, 2026 · NCT07137338HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
- University of California Davis, Sacramento
RecruitingObservational studyHealthy volunteers welcome
Ages 30 and older · All sexes · Updated Sep 29, 2026 · NCT05873634A Study to Investigate CV Outcomes With Elecoglipron Compared With Placebo in Adult Participants With HFpEF or HFmrEF
- Research Site, Beverly Hills
- Research Site, Huntington Beach
- Research Site, Huntington Park
- and 7 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07761117Evaluation of Liver Stiffness Performance, by FibroScan®, to Detect Elevated Central Venous Pressure (CVP)
- Keck Medicine of USC-Norris Healthcare Center - Transplant Clinic, Los Angeles
Recruiting
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT07222813A Study to Determine the Efficacy and Safety of Finerenone and SGLT2i in Combination in Hospitalized Patients With Heart Failure (CONFIRMATION-HF)
- Chula Vista, CA Investigative Site CON-10111, Chula Vista
- CON-10075 El Centro, CA Investigational Site, El Centro
- CON-10024 Sacramento, CA Investigational Site, Sacramento
- and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06024746A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
- Chula Vista, CA Investigative Site 10111, Chula Vista
- Huntington Beach, CA Investigative Site 10031, Huntington Beach
- Los Angeles, CA Investigative Site 10089, Los Angeles
- and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 10, 2026 · NCT06008197Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure
- University of California, San Francisco, San Francisco
Recruiting
Ages 18 and older · All sexes · Updated Sep 2, 2026 · NCT03586336AMBER-HFpEF: Assessment of CK-4021586 in a Multi-Center, Blinded Evaluation of Safety and Tolerability Results in HFpEF
- BioSolutions Clinical Research Center, Imperial
- Profound Research LLC, Pasadena
- University of California, San Francisco - Heart and Vascular Center, San Francisco
- and 2 more
RecruitingPhase 2
Ages 40 to 85 · All sexes · Updated Aug 27, 2026 · NCT06793371Retinal Fundus Imaging and OCT Imaging for Ocular Detection of ATTR-CM
- Research Site, Palo Alto
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 26, 2026 · NCT07690436Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
- John Muir Health, Concord
- Zuckerberg San Francisco General, San Francisco
- University of California San Francisco, San Francisco
Recruiting
Ages 21 and older · All sexes · Updated Aug 25, 2026 · NCT05677100Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
- Lucile Packard Children's Hospital, Palo Alto
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 · All sexes · Updated Aug 21, 2026 · NCT04278404A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive-HCM)
- Keck School of Medicine of USC-Usc, Los Angeles
- Stanford Health Care Hospital & Clinics, Palo Alto
- University Of California San Francisco Medical Center, San Francisco
RecruitingObservational study
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT05489705A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity
- InvivoCure -2, Alhambra
- Cardio Research of S. Cal, Beverly Hills
- Westside Medical Associates Los Angeles, Beverly Hills
- and 30 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001Alleviant ALLAY-HF Study
- Memorial Care Long Beach Medical Center, Long Beach
- UC Davis Medical Center, Sacramento
- Scripps Clinical Research Services, San Diego
- and 2 more
Recruiting
Ages 40 and older · All sexes · Updated Aug 14, 2026 · NCT05685303OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels
- Cedars-Sinai Medical Center, Los Angeles
- Stanford University, Palo Alto
RecruitingObservational study
Ages 18 to 99 · All sexes · Updated Aug 11, 2026 · NCT06939751From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.