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Heart Failure clinical trials in Orange, CA

5 studies for Heart Failure are looking for participants at sites in and around Orange (within about 30 miles). Open a study to see who can join and how to contact the study team.

Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction

RecruitingPhase 3
  • University of California, Irvine Medical Center, Orange
Ages 18 to 85 · All sexes · Updated Sep 24, 2026 · NCT06736574

A Study to Test Whether Vicadrostat in Combination With Empagliflozin Helps People With Heart Failure

RecruitingPhase 3
  • University of California Irvine, Orange
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT06424288

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

RecruitingPhase 3
  • University of California Irvine, Orange
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

AI-Enabled Direct-from-ECG Ejection Fraction (EF) Severity Assessment Using COR ECG Wearable Monitor

RecruitingObservational studyHealthy volunteers welcome
  • Orange County Heart Institute, Orange
Ages 18 and older · All sexes · Updated Jun 1, 2026 · NCT06699056

About Heart Failure

Heart failure, or congestive heart failure (CHF), means the heart can't pump enough blood. Learn about the signs, symptoms, and causes.

More about Heart Failure on MedlinePlus

Heart Failure trials in other cities

Other studies in Orange

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.