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Melanoma clinical trials in Birmingham, AL

11 studies for Melanoma are looking for participants at sites in and around Birmingham (within about 30 miles). Open a study to see who can join and how to contact the study team.

DESTINY-PANTUMOUR04

RecruitingObservational study
  • Research Site, Birmingham
Ages 18 to 130 · All sexes · Updated Sep 25, 2026 · NCT07124000

Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma.

RecruitingPhase 3
  • University of Alabama at Birmingham: The Kirklin Clinic, Birmingham
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT05727904

Pan-tumor MRD Study

RecruitingObservational study
  • Alabama Oncology, Birmingham
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT06605404

Comparing the Effectiveness of Less Invasive Procedures With the Current Standard of Care for the Treatment of Older Adults With Early-Stage Melanoma

RecruitingPhase 3
  • University of Alabama at Birmingham Cancer Center, Birmingham
Ages 75 and older · All sexes · Updated Sep 24, 2026 · NCT07068074

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • University of Alabama at Birmingham Cancer Center, Birmingham
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

RecruitingObservational study
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT05059444

DOC1021 Dendritic Cell Immunotherapy for Refractory Melanoma

RecruitingPhase 1/2
  • The University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07288112

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

RecruitingPhase 1/2
  • Children's Hospital of Alabama, Birmingham
12 Months – 30 Years · All sexes · Updated Aug 25, 2026 · NCT04851119

Project: Every Child for Younger Patients With Cancer

RecruitingObservational study
  • Children's Hospital of Alabama, Birmingham
Up to age 25 · All sexes · Updated Aug 25, 2026 · NCT02402244

Comparative Effectiveness Trial of Two Supportive Cancer Care Delivery Models for Adults With Cancer

Recruiting
  • University of Alabama at Birmingham, Birmingham
Ages 18 and older · All sexes · Updated Apr 30, 2026 · NCT05297734

SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry

RecruitingObservational study
  • Massive Bio SYNERGY-AI site, Birmingham
All ages · All sexes · Updated Oct 28, 2025 · NCT03452774

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Birmingham

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.