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Melanoma clinical trials in Saint Paul, MN

6 studies for Melanoma are looking for participants at sites in and around Saint Paul (within about 30 miles). Open a study to see who can join and how to contact the study team.

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Saint John's Hospital - Healtheast, Maplewood · 5 mi away
  • and 1 more
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05136196

A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors

RecruitingPhase 2
  • Health Partners Cancer Center at Regions Hospital, Saint Paul
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT06172478

A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases

RecruitingPhase 2
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Sep 15, 2026 · NCT04511013

Collecting Blood Samples From Patients With and Without Cancer to Evaluate Tests for Early Cancer Detection

RecruitingObservational studyHealthy volunteers welcome
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 40 to 75 · All sexes · Updated Sep 2, 2026 · NCT05334069

Assessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology Clinics

RecruitingObservational study
  • Regions Hospital, Saint Paul
  • United Hospital, Saint Paul
  • Minnesota Oncology Hematology PA-Maplewood, Maplewood · 5 mi away
  • and 3 more
Ages 18 and older · All sexes · Updated Mar 17, 2026 · NCT06418204

A Phase 1/2a Study of DB-1311/BNT324 in Advanced/Metastatic Solid Tumors

RecruitingPhase 1/2
  • Research Site 121, Saint Paul
Ages 18 and older · All sexes · Updated Nov 21, 2025 · NCT05914116

About Melanoma

Melanoma is the most serious type of skin cancer. Most have a black or black-blue area. Learn the 'ABCDE' of what to watch for and treatment options.

More about Melanoma on MedlinePlus

Melanoma trials in other cities

Other studies in Saint Paul

From ClinicalTrials.gov, data retrieved Oct 1, 2026. Each study sets its own eligibility; the study team decides who can join.