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Multiple Myeloma clinical trials in Illinois

30 studies for Multiple Myeloma are looking for participants at sites in Illinois.

Cities in Illinois

Testing the Investigational Medication Combination of Daratumumab and Teclistamab Compared to the Usual Treatment (Daratumumab, Pomalidomide, Dexamethasone or Daratumumab, Carfilzomib, Dexamethasone) for Patients With High-risk Multiple Myeloma Refractory or in First Relapse

  • Illinois CancerCare-Bloomington, Bloomington
  • Illinois CancerCare-Canton, Canton
  • Illinois CancerCare-Carthage, Carthage
  • and 10 more
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT06948084

A Long-term Study for Participants Previously Treated With Ciltacabtagene Autoleucel

  • Northwestern University, Chicago
  • University of Chicago, Chicago
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05201781

A Study Comparing JNJ-79635322 and an Anti-B-cell Maturation Antigen (BCMA)xCD3 Bispecific Antibody in Participants With Relapsed or Refractory Multiple Myeloma

  • City of Hope Chicago, Zion
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07258511

A Study Comparing JNJ-79635322 and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

  • Rush University System for Health, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07518186

A Study of Teclistamab in Combination With Daratumumab and Lenalidomide (Tec-DR) and Talquetamab in Combination With Daratumumab and Lenalidomide (Tal-DR) in Participants With Newly Diagnosed Multiple Myeloma

  • University Of Illinois Medical Center, Chicago
  • Loyola University Medical Center, Maywood
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT05552222

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed Multiple Myeloma

  • University of Chicago Medicine Comprehensive Cancer Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT05789303

TAPUR: Testing the Use of Food and Drug Administration (FDA) Approved Drugs That Target a Specific Abnormality in a Tumor Gene in People With Advanced Stage Cancer

  • Cancer Treatment Centers of America-Chicago, Chicago
RecruitingPhase 2
Ages 12 and older · All sexes · Updated Sep 22, 2026 · NCT02693535

Study of Arlocabtagene Autoleucel (BMS-986393) a GPRC5D-directed CAR T Cell Therapy in Adult Participants With Relapsed or Refractory Multiple Myeloma

  • Northwestern Memorial Hospital, Chicago
  • University of Chicago Medical Center, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT06297226

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Relapsed Refractory Multiple Myeloma (DURGA-4)

  • Research Site, Chicago
  • Research Site, Park Ridge
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07391657

Post-Autologous Transplant Maintenance With Isatuximab and Lenalidomide in Minimal Residual Disease Positive Multiple Myeloma

  • University of Illinois at Chicago, Chicago
RecruitingPhase 2
Ages 18 and older · All sexes · Updated Aug 28, 2026 · NCT05344833

MagnetisMM-32: A Study to Learn About the Study Medicine Called Elranatamab in People With Multiple Myeloma (MM) That Has Come Back After Taking Other Treatments (Including Prior Treatment With an Anti-CD38 Antibody and Lenalidomide)

  • Endeavor Health - Swedish Hospital, Chicago
  • Endeavor Health - Evanston Hospital, Evanston
  • Endeavor Health - Glenbrook Hospital Ambulatory Care Center, Glenview
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 24, 2026 · NCT06152575

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

  • OSF Saint Anthony's Health Center, Alton
  • Advocate Outpatient Center - Aurora, Aurora
  • Advocate Good Shepherd Hospital, Barrington
  • and 40 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 19, 2026 · NCT04566328

AZD0120 in Relapsed/Refractory Multiple Myeloma (DURGA-1)

  • Research Site, Chicago
RecruitingPhase 1/2
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT05850234

Study of AZD0120 in Newly Diagnosed Multiple Myeloma Ineligible for ASCT

  • Research Site, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 14, 2026 · NCT07764978

A Study to Learn About the Effects of Cemsidomide in Combination With Elranatamab in Relapsed/Refractory Multiple Myeloma Subjects

  • Loyola University Medical Center, Maywood
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Aug 12, 2026 · NCT07280013

Mosaic Trial for Stem Cell Transplant Recipients

  • Northwestern University Feinberg School of Medicine, Chicago
Recruiting
Ages 18 and older · All sexes · Updated Aug 3, 2026 · NCT06960993

Moving Forward With Myeloma: A Lifestyle Intervention for Individuals With Multiple Myeloma

  • Loyola University Chicago, Maywood
Recruiting
Ages 18 and older · All sexes · Updated Jul 22, 2026 · NCT07236502

A Study to Assess Adverse Events of Intravenously (IV) Infused Etentamig (ABBV-383) in Adult Participants With Relapsed or Refractory Multiple Myeloma

  • Hope And Healing Cancer Services /ID# 268536, Hinsdale
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jul 13, 2026 · NCT05650632

Integrated Cancer Repository for Cancer Research

  • Rush-Copley Cancer Care Center, Aurora
  • Rush-Copley Healthcare Center, Yorkville
RecruitingObservational studyHealthy volunteers welcome
Ages 19 to 110 · All sexes · Updated Jun 29, 2026 · NCT02012699

Personalized Autologous Transplant for Multiple Myeloma

  • University Illinois Chicago, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Jun 15, 2026 · NCT04483206

Comparing Combinations of Drugs to Treat Newly Diagnosed Multiple Myeloma (NDMM) When a Stem Cell Transplant is Not a Medically Suitable Treatment

  • Saint Anthony's Health, Alton
  • Rush - Copley Medical Center, Aurora
  • Saint Joseph Medical Center, Bloomington
  • and 41 more
RecruitingPhase 3
All ages · All sexes · Updated Jun 10, 2026 · NCT05561387

Phase 3 Study of Teclistamab in Combination With Lenalidomide and Teclistamab Alone Versus Lenalidomide Alone in Participants With Newly Diagnosed Multiple Myeloma as Maintenance Therapy Following Autologous Stem Cell Transplantation

  • University of Chicago, Chicago
  • University of Illinois Medical Center at Chicago, Chicago
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Jun 4, 2026 · NCT05243797

Study of Oral Administration of LP-118 in Patients With Relapsed or Refractory CLL, SLL, MDS, MDS/MPN, AML, CMML-2, MPN-BP, ALL, MF, NHL, RT, MM or T-PLL.

  • University of Chicago, Chicago
RecruitingPhase 1
Ages 13 and older · All sexes · Updated May 5, 2026 · NCT04771572

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma (TRIgnite-1)

  • University of Chicago Medical Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Apr 1, 2026 · NCT05862012

Hypofractionation (Radiation) Trial for Multiple Myeloma

  • The University of Chicago Comprehensive Cancer Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Mar 30, 2026 · NCT06270888

A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)

  • Northwestern, Chicago
RecruitingPhase 1/2
Ages 12 and older · All sexes · Updated Mar 24, 2026 · NCT04988555

Real World Treatment Experience of Patients With Breast, Lung, Ovarian, Multiple Myeloma, or Acute Myelogenous Leukemia Using Remote Symptom Monitoring

  • Northshore University Health System, Evanston
RecruitingObservational study
Ages 18 and older · All sexes · Updated Feb 23, 2026 · NCT05974150

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

  • City of Hope at Chicago, Zion
RecruitingObservational studyHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Feb 20, 2026 · NCT07225738

Free From Maintenance Drug Therapy in Multiple Myeloma (The FREEDMM Trial) for Minimal Residual Disease (MRD

  • University of Illinois Cancer Center, Chicago
RecruitingPhase 1
Ages 18 and older · All sexes · Updated Dec 18, 2025 · NCT05192122

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.