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Obesity clinical trials in Illinois

55 studies for Obesity are looking for participants at sites in Illinois.

Cities in Illinois

Home Self-administration of Maridebart Cafraglutide With Autoinjector in Adults Living With Obesity or Overweight

  • Alliance For Multispecialty Research - Oak Brook, Oak Brook
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07871409

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • Elevate Clinical Research, Gurnee
  • Knownwell, Schaumburg
  • Endeavor Health, Skokie
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351045

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

  • Research Site, Champaign
  • Research Site, Chicago
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07776509

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • Central Illinois Diabetes and Clinical Research, Springfield
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 9, 2026 ยท NCT07351058

Scalable TELeheaLth Cancer CARe: The STELLAR Program to Treat Cancer Risk Behaviors

  • Northwestern University-Feinberg School of Medicine, Chicago
Recruiting
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT05687604

Study of Olatorepatide in Adult Participants Living With Overweight or Obesity Without Diabetes

  • Charter Research LLC - Chicago, Chicago
  • Flourish Research, Ravenswood Rheumatology, Chicago
  • AMR Clinical - Chicago Oak Brook, Oak Brook
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07685808

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

  • Endeavor Health, Skokie
  • Central Illinois Diabetes and Clinical Research, a Division of Prairie Education and Research Cooper, Springfield
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Nov 6, 2026 ยท NCT07575399

A Study to Learn About Study Medicine Called Berobenatide in Adults With Knee Pain and Overweight or Obesity (VESPER-OA 1)

  • Northwestern Medicine, Chicago
  • Northwestern Memorial Hospital, Diagnostic Testing Center (Phlebotomy/EKG), Chicago
  • Northwestern Memorial Hospital, Investigational Drug Service, Chicago
  • and 2 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07919678

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

  • Cedar Crosse Research Center, Chicago
  • Northwestern University, Chicago
  • Endeavor Health - Family Medicine Administration, Evanston
  • and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 5, 2026 ยท NCT07595549

Efficacy, Safety, and Pharmacokinetics of Tirzepatide (LY3298176) Once Weekly Versus Placebo in Pediatric Participants 6 to Less Than 12 Years of Age Who Have Obesity (ADVANCE-SURMOUNT-KIDS)

  • Ann and Robert H Lurie Children's Hospital of Chicago, Chicago
  • University of Illinois at Chicago, Chicago
RecruitingPhase 3
Ages 6 to 11 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07817875

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • NorthShore University Health System, Skokie
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Great Lakes Clinical Trials - Ravenswood, Chicago
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07392190

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

  • Great Lakes Clinical Trials - Ravenswood, Chicago
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Nov 4, 2026 ยท NCT07353931

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Rush University Medical Center, Chicago
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Rush University Medical Center, Chicago
RecruitingPhase 3
Ages 18 to 70 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06937086

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Ann and Robert Lurie Children's Hospital of Chicago, Chicago
  • University of Illinois at Chicago, Chicago
RecruitingPhase 3
Ages 6 to 17 ยท All sexes ยท Updated Nov 4, 2026 ยท NCT06672549

A Study of Clazakizumab (LY5724886) in Adults With Elevated hsCRP and at Increased Risk for Cardiovascular Event

  • Accellacare - DuPage, Lombard
RecruitingPhase 2
Ages 18 and older ยท All sexes ยท Updated Nov 3, 2026 ยท NCT07783802

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Champaign
  • Research Site, Chicago
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 30, 2026 ยท NCT07784725

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Chicago Medical Research LLC, Hazel Crest
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Oct 29, 2026 ยท NCT07037459

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Chicago
  • Research Site, Melrose Park
  • Research Site, Oak Brook
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Oct 28, 2026 ยท NCT07784270

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • Great Lakes Clinical Trials - West Wilson Avenue /ID# 282378, Chicago
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 27, 2026 ยท NCT07752979

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

  • Christie Clinic, Champaign
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 26, 2026 ยท NCT07837973

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • Great Lakes Clinical Trials - Ravenswood, Chicago
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 8, 2026 ยท NCT07589608

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • Great Lakes Clinical Trials - Ravenswood, Chicago
RecruitingPhase 2
Ages 18 to 75 ยท All sexes ยท Updated Oct 7, 2026 ยท NCT06143956

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Flourish Research - Great Lakes Clinical Trials, Chicago
  • Endeavor Health, Skokie
  • Evanston Premier Healthcare Research LLC, Skokie
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT07684235

A Trial to Examine the Effects of a Weight Loss Program Emphasizing Protein, Dietary Fiber, and Exercise (30-30-30 Plan)

  • Biofortis Clinical Research, Addison
  • Illinois Institute of Technology, Chicago
RecruitingHealthy volunteers welcome
Ages 18 to 69 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT07789769

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

  • Endeavor Health, Skokie
RecruitingPhase 3
Ages 18 to 99 ยท All sexes ยท Updated Oct 5, 2026 ยท NCT07684144

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

  • Great Lakes Clinical Trials, Chicago
  • Clinical Investigation Spec Gurnee, Gurnee
  • Endeavor Health, Skokie
  • and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07720271

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • Chicago Research Center, Inc, Chicago
  • Endeavor Health, Skokie
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07668414

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

  • Endeavor Health, Skokie
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 24, 2026 ยท NCT07339423

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Schaumburg
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, Schaumburg
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 16, 2026 ยท NCT07743463

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

  • Walgreens - Store 11760, Oak Park
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 4, 2026 ยท NCT07745504

BRIDGE & Friends Trial

  • University of Illinois Chicago, Chicago
RecruitingHealthy volunteers welcome
Ages 50 to 79 ยท All sexes ยท Updated Sep 1, 2026 ยท NCT07798557

Assess the Effects of Replacing Foods High in Refined Carbohydrates With Avocado on Biomarkers of Inflammation.

  • Illinois Institute of Technology, Chicago
RecruitingHealthy volunteers welcome
Ages 21 to 74 ยท All sexes ยท Updated Aug 27, 2026 ยท NCT07566325

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

  • Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago
RecruitingPhase 2
Ages 7 to 25 ยท All sexes ยท Updated Aug 19, 2026 ยท NCT05082519

Digital InteGrated Behavioral treatmeNt for Comorbid obesITy and deprEssion Among Racial and Ethnic Adults Age 50 and Older

  • Department of Medicine, Vitoux Program on Aging and Prevention, Chicago
Recruiting
Ages 50 to 74 ยท All sexes ยท Updated Aug 18, 2026 ยท NCT06636058

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Chicago Clinical Research Institute INC, Chicago
  • Univer Of Illinois at Chicago, Chicago
  • Eagle Clinical Research, Chicago
  • and 3 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Aug 18, 2026 ยท NCT07567001

From ClinicalTrials.gov, data retrieved Nov 15, 2026. Each study sets its own eligibility; the study team decides who can join.