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Obesity clinical trials in North Carolina

62 studies for Obesity are looking for participants at sites in North Carolina.

Cities in North Carolina

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • PharmQuest Life Sciences LLC, Greensboro
  • Piedmont Healthcare/Research, Statesville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

  • Medication Management, LLC, Greensboro
  • Accellacare - Wilmington, Wilmington
  • Jeffrey Coleman, OD, Wilmington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

  • Medication Mgmnt, LLC_Grnsboro, Greensboro
  • Accellacare of Raleigh, Raleigh
  • Accellacare-Salisbury PMG Res, Salisbury
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

  • TMA Headlands, Wilmington
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07837973

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • Medication Management /ID# 281965, Greensboro
  • Monroe Biomedical Research /ID# 282009, Monroe
  • Centricity Research - Morehead city /ID# 283264, Morehead City
  • and 2 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07752979

AMAZE 1: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Lose Weight

  • UNC Eastowne Medical Office, Chapel Hill
  • PharmQuest Life Sciences LLC, Greensboro
  • Accellacare and KDCILM, LLC, Wilmington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 24, 2026 · NCT07339423

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • UNC Children's Hospital, Chapel Hill
  • Duke Children's Primary Care, Durham
  • Lucas Research, Inc, Morehead City
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Coastal Research Institute - Fayetteville, Fayetteville
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Coastal Research Institute - Fayetteville, Fayetteville
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)

  • University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 to 75 · All sexes · Updated Sep 23, 2026 · NCT06724406

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

  • Monroe Biomedical Research, Monroe
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Novant Health Heart and Vascular Institute, Charlotte
  • Velocity Clinical Research - Durham, Durham
  • Moses H Cone Memorial Hospital, Greensboro
  • and 7 more
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Monroe
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • PharmQuest Life Sciences, LLC, Greensboro
  • West Clinical Research, Morehead City
  • Trial Management Associates - Wilmington - Floral Parkway, Wilmington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • University of North Carolina Medical Center, Chapel Hill
  • Medication Management, Greensboro
  • Carteret Medical Group, Morehead City
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • Medication Management, Greensboro
  • Monroe Biomedical Research, Monroe
  • Lucas Research, Inc, Morehead City
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee

  • Carolina Research Center, Shelby
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07153471

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Charlotte
  • AURORA-2 Clinical Site, Durham
  • AURORA-2 Clinical Site, Greenville
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, Charlotte
  • AURORA-1 Clinical Site, Greenville
  • AURORA-1 Clinical Site, Morehead City
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

Maridebart Cafraglutide in Heart Failure With Preserved or Mildly Reduced Ejection Fraction and Obesity

  • Asheville Cardiology Associates, Asheville
  • Duke University Health System, Durham
  • Ima Clinical Research - Lenoir, Lenoir
  • and 2 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 16, 2026 · NCT07037459

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

  • Lucas Research, Inc., Morehead City
  • Shelby Clinical Research, Shelby
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • Centricity Research Morehead City Multispeciality, Morehead City
  • Wake Forest University Health Sciences, Winston-Salem
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

Tirzepatide in Obesity-Driven Endometrial Cancer

  • Lineberger Comprehensive Cancer Center, Chapel Hill
RecruitingEarly phase 1
Ages 18 and older · Women · Updated Sep 11, 2026 · NCT07065552

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Charlotte
  • ACCOMPLISH-2 Research Site, Durham
  • ACCOMPLISH-2 Research Site, Fayetteville
  • and 2 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • Medication Management, Greensboro
  • Monroe Biomedical Research, Monroe
  • Lucas Research, Inc, Morehead City
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

  • Revival Research Institute, LLC, Cary
  • Onsite Clinical Solutions - Huntersville, Huntersville
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight

  • PharmQuest, Greensboro
  • KDCILM, LLC & Accellacare US, Inc., Wilmington
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07745504

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Accellacare of Hickory, Hickory
  • Carolina Research Center Inc, Shelby
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

  • Kailera Clinical Site, Greensboro
  • Kailera Clinical Site, Monroe
  • Kailera Clinical Site, Morehead City
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

  • West Clinical Research, Morehead City
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

  • Kailera Clinical Site, Morehead City
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284875

Efficacy and Safety of Ribupatide Administered Once Weekly Compared With Semaglutide and Placebo in Participants Living With Obesity Who Do Not Have Diabetes

  • Kailera Clinical Site, Morehead City
  • Kailera Clinical Site, Morrisville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 1, 2026 · NCT07284979

Efficacy, Safety and Tolerability of Switching From Glucagon-like Peptide-1 Receptor Agonists (GLP-1RA) to Maridebart Cafraglutide in Adults With Obesity or Overweight (MARITIME-SWITCH)

  • Centricity Research Morehead City Specialty, Morehead City
  • Accellacare of Raleigh, Raleigh
  • Accellacare Research of Wilmington, Wilmington
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Aug 27, 2026 · NCT07575399

A Study to Evaluate Effect of AZD6234 in Adult Participants With Obesity or Overweight With Weight-related Comorbidity Without Type 2 Diabetes Mellitus

  • Research Site, Statesville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 25, 2026 · NCT07784725

Using Tailored mHealth Strategies to Promote Weight Management Among Adolescent and Young Adult Cancer Survivors

  • University of North Carolina at Chapel Hill, Chapel Hill
Recruiting
Ages 18 to 39 · All sexes · Updated Aug 24, 2026 · NCT06848491

Caloric Restriction and Activity to Reduce Chemoresistance in B-ALL

  • Levine Children's Hospital, Charlotte
RecruitingPhase 2
Ages 7 to 25 · All sexes · Updated Aug 19, 2026 · NCT05082519

A Research Study to Look at How Well NNC0487-0111 Works Compared to Placebo in People With Heart Failure and Obesity

  • Peak Clinical Trials, Apex
  • Hawthorne Health NC, Concord
  • Duke University, Durham
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT07567001

AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain

  • Piedmont Healthcare/Research, Statesville
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Aug 17, 2026 · NCT07509307

Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea Not on Positive Airway Pressure (PAP) Therapy

  • Monroe Biomedical Research, Monroe
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Aug 14, 2026 · NCT07226765

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.