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Overweight clinical trials in California

64 studies for Overweight are looking for participants at sites in California.

Cities in California

A Research Study Investigating How Well the Medicine Zenagamtide Helps People With Excess Body Weight Lose Weight Compared to Semaglutide

  • First Valley Medical Group, Lancaster
  • Desert Oasis Healthcare, Palm Springs
  • Western University of Health Sciences, Pomona
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07668414

A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity

  • San Fernando Valley Health Institute, Canoga Park
  • Headlands Research California, LLC, Escondido
  • ImmuniMet, LLC, Modesto
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07595549

A Study of Orforglipron in Participants With Overweight at Risk of Development of Obesity-Related Complications or Progression to Class 1 Obesity

  • Orange County Research Center, Lake Forest
  • Healthy Brain Clinic, Long Beach
  • Los Angeles Institute for Metabolic Research, Los Angeles
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07794579

AMAZE 9: A Research Study Investigating How Well Zenagamtide Tablets Help People With Excess Body Weight Lose Weight

  • Providence Medical Foundation, Fullerton
  • Torrance Clinical Research Institute, Inc., Lomita
  • Diablo Clinical Research, Inc., Walnut Creek
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 28, 2026 · NCT07720271

Study to Assess the Effect and Safety of ALV-100 on Maintenance of Weight Loss

  • Profound Research, Oceanside
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 28, 2026 · NCT07837973

Safety and Efficacy of ABBV-295 in Adults With Obesity or Overweight With Weight-Related Comorbidities

  • John Muir Health - Concord /ID# 282469, Concord
  • NorCal Medical Research /ID# 283117, Greenbrae
  • Los Angeles Institute for Metabolic Research /ID# 282059, Los Angeles
  • and 4 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 25, 2026 · NCT07752979

Safety and Drug Concentrations of REGN20934 in Adults With Overweight or Obesity

  • Parexel International, Glendale
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 · All sexes · Updated Sep 25, 2026 · NCT07594093

A Study to Evaluate Effect of AZD6234 as an Adjunct to Incretin-based Therapies in Adult Participants With Obesity or Overweight With Weight-related Comorbidity With or Without Type 2 Diabetes Mellitus

  • Research Site, Escondido
  • Research Site, Lincoln
  • Research Site, Walnut Creek
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 25, 2026 · NCT07776509

A Platform Trial for Pediatric Participants With Obesity or Overweight (LY900040)

  • Loma Linda University School of Medicine, Loma Linda
  • Childrens Hospital of Los Angeles, Los Angeles
  • UCLA Mattel Children's Hospital, Los Angeles
  • and 2 more
RecruitingPhase 3
Ages 6 to 17 · All sexes · Updated Sep 24, 2026 · NCT06672549

Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight

  • Smart Cures Clinical Research, Anaheim
  • Cedars-Sinai Medical Center, Beverly Hills
  • United Medical Doctors - Los Alamitos, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937099

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

  • Smart Cures Clinical Research, Anaheim
  • Cedars-Sinai Medical Center, Beverly Hills
  • United Medical Doctors - Los Alamitos, Los Alamitos
  • and 1 more
RecruitingPhase 3
Ages 18 to 70 · All sexes · Updated Sep 24, 2026 · NCT06937086

A Study of Eloralintide (LY3841136) in Participants With Obesity, or Overweight Without Type 2 Diabetes

  • Neighborhood Healthcare Institute of Health, Escondido
  • Ark Clinical Research - Fountain Valley, Fountain Valley
  • Desert Oasis Healthcare Medical Group, Palm Springs
  • and 4 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07321886

Evaluating the Impact of Maridebart Cafraglutide on Cardiovascular Outcomes in Participants With Atherosclerotic Cardiovascular Disease and Overweight or Obesity

  • Valley Clinical Trials, LLC dba Flourish Research, Covina
  • Velocity Clinical Research- Huntington Park, Huntington Park
  • Orange County Research Center, Lake Forest
  • and 5 more
RecruitingPhase 3
Ages 45 to 99 · All sexes · Updated Sep 22, 2026 · NCT07037433

A Study to Evaluate Effect of AZD6234 in Adult Participants With Type 2 Diabetes Mellitus and Obesity or Overweight

  • Research Site, Bakersfield
  • Research Site, Gardena
  • Research Site, Lincoln
  • and 2 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07784270

A Study of Eloralintide (LY3841136) in Participants With Obesity or Overweight, and Type 2 Diabetes

  • San Fernando Valley Health Institute, Canoga Park
  • AMCR Institute, Escondido
  • NorCal Medical Research, Inc, Greenbrae
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07282600

A Study of Eloralintide (LY3841136) in Participants With Obstructive Sleep Apnea and Obesity or Overweight

  • Ark Clinical Research, Long Beach
  • Collaborative Neuroscience Research, LLC, Los Alamitos
  • Artemis Institute for Clinical Research, Riverside
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07369011

A Study of Eloralintide (LY3841136) in Participants With Persistent Obesity Who Are Treated With a Weekly Incretin

  • Irvine Clinical Research, Irvine
  • Scripps Whittier Diabetes Institute, La Jolla
  • EndoTrials Center for Clinical Research, La Mesa
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07392190

A Study to Investigate Weight Management With Macupatide and Eloralintide, Alone or in Combination, in Adult Participants With Obesity or Overweight

  • NorCal Medical Research, Inc, Greenbrae
  • Velocity Clinical Research, Huntington Park, Huntington Park
  • Peninsula Research Associates, Rolling Hills Estates
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 22, 2026 · NCT07589608

CHOICE to AVOID or RESIST

  • Cedars-Sinai Medical Center, Beverly Hills
RecruitingHealthy volunteers welcome
Ages 18 to 80 · All sexes · Updated Sep 22, 2026 · NCT06521021

Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight

  • Ark Clinical Research - Fountain Valley, Fountain Valley
  • Wolverine Clinical Trials, Santa Ana
  • Encompass Clinical Research, Spring Valley
  • and 1 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 22, 2026 · NCT07353931

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Type 2 Diabetes

  • AURORA-2 Clinical Site, Banning
  • AURORA-2 Clinical Site, Chula Vista
  • AURORA-2 Clinical Site, Covina
  • and 6 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743450

A Study of Once-daily Oral ASC30 to Evaluate the Efficacy and Safety in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities

  • AURORA-1 Clinical Site, Banning
  • AURORA-1 Clinical Site, Chula Vista
  • AURORA-1 Clinical Site, Covina
  • and 5 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 16, 2026 · NCT07743463

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight Without Type 2 Diabetes

  • University of California Irvine, Irvine
  • Artemis Institute for Clinical Research, LLC, San Diego
  • Diablo Clinical Research, Inc., Walnut Creek
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351045

A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide

  • Wolverine Clinical Trials, Santa Ana
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 14, 2026 · NCT06897475

A Clinical Study to Evaluate the Effects of Enicepatide (RO7795068) in Participants With Obesity or Overweight and Type 2 Diabetes

  • Orange County Research Center, Lake Forest
  • Ark Clinical Research, Long Beach
  • Catalina Research Institute, LLC, Montclair
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 14, 2026 · NCT07351058

A Study of Aleniglipron in Adults With Obesity or Overweight and Type 2 Diabetes Mellitus (ACCOMPLISH-2)

  • ACCOMPLISH-2 Research Site, Escondido
  • ACCOMPLISH-2 Research Site, Fountain Valley
  • ACCOMPLISH-2 Research Site, La Jolla
  • and 4 more
RecruitingPhase 3Healthy volunteers welcome
Ages 18 to 79 · All sexes · Updated Sep 11, 2026 · NCT07654374

A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity

  • PAREXEL Glendale/LA EPCU, Glendale
RecruitingPhase 1
Ages 18 to 55 · All sexes · Updated Sep 9, 2026 · NCT07566390

Research Study on How Well Oral Semaglutide Works for Weight Loss in Adults With Excess Body Weight

  • Headlands Research California, LLC, Escondido
  • National Research Institute - Huntington Park, Huntington Park
  • Los Angeles Institute for Metabolic Research, Los Angeles
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 9, 2026 · NCT07770841

Effects of Dietary Supplements on Muscle Mass and Function While Using GLP-1 Medication

  • UCLA Center for Human Nutrition, Los Angeles
RecruitingHealthy volunteers welcome
Ages 18 and older · All sexes · Updated Sep 8, 2026 · NCT07806838

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

  • NorCal Medical Research, Inc, Greenbrae
  • Velocity Clinical Research, Huntington Park, Huntington Park
  • Peninsula Research Associates, Rolling Hills Estates
  • and 1 more
RecruitingPhase 2
Ages 18 to 75 · All sexes · Updated Sep 8, 2026 · NCT06143956

A Study to Investigate the Effectiveness of Tirzepatide (LY3298176) Following Initiation of Ixekizumab (LY2439821) in Participants With Moderate-to-Severe Plaque PsO and Obesity or Overweight in Clinical Practice (TOGETHER AMPLIFY-PsO)

  • First OC Dermatology Research Inc, Fountain Valley
  • Center For Dermatology Clinical Research, Inc., Fremont
  • Metropolis Dermatology, Los Angeles
  • and 1 more
RecruitingPhase 4
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT06857942

AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight

  • Torrance Clinical Research Institute, Inc., Lomita
  • Diablo Clinical Research, Inc., Walnut Creek
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 4, 2026 · NCT07533175

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)

  • Ark Clinical Research- Tustin, Fountain Valley
  • Long Beach Clinical Trials Services Inc, Long Beach
  • Ark Clinical Research- Long Beach, Long Beach
  • and 6 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684235

Efficacy and Safety of Ribupatide Administered Once Weekly in Participants Living With Obesity or Overweight and Diabetes

  • Kailera Clinical Site, Escondido
  • Kailera Clinical Site, La Mesa
  • Kailera Clinical Site, Montclair
  • and 3 more
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284901

Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-2-EXTENSION)

  • San Fernando Valley Health Institute, Canoga Park
  • Core Healthcare Group, Cerritos
  • Velocity Clinical Research Chula Vista, Chula Vista
  • and 1 more
RecruitingPhase 3
Ages 18 to 99 · All sexes · Updated Sep 3, 2026 · NCT07684144

Efficacy and Safety of Ribupatide in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

  • Kailera Clinical Site, Escondido
  • Kailera Clinical Site, Toluca Lake
RecruitingPhase 3
Ages 18 and older · All sexes · Updated Sep 3, 2026 · NCT07284875

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

  • Neighborhood Healthcare, Escondido
RecruitingPhase 3
Ages 8 to 18 · All sexes · Updated Aug 31, 2026 · NCT07253285

Effects of Watermelon or Low-fat Cookie Consumption on Wellness

  • School of Exercise and Nutritional Sciences, San Diego
RecruitingHealthy volunteers welcome
Ages 18 to 50 · All sexes · Updated Aug 28, 2026 · NCT06323070

From ClinicalTrials.gov, data retrieved Sep 29, 2026. Each study sets its own eligibility; the study team decides who can join.