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Pain clinical trials in California

30 studies for Pain are looking for participants at sites in California.

Cities in California

An Open-Label, Safety and Efficacy Study of Cebranopadol in Participants With Acute Pain With Surgical or Non-Surgical Origin

  • Adneuris Site 001118, Riverside
RecruitingPhase 3
Ages 18 to 75 ยท All sexes ยท Updated Sep 28, 2026 ยท NCT07845071

Enhanced Pain Coping in Cancer (EPIC): A Study of Managing Treatment-Related Joint Pain in Breast Cancer Survivors

  • University of California San Diego (Data collection and Data analysis), San Diego
RecruitingPhase 2
Ages 18 and older ยท Women ยท Updated Sep 22, 2026 ยท NCT06728579

Evaluation of IV AMBTX-01 (Neridronate) for Treatment of CRPS Type 1 (CRPS-RISE)

  • Ambros Clinical Trial Site, La Jolla
  • Ambros Clinical Trial Site, Napa
  • Ambros Clinical Trial Site, Pasadena
  • and 1 more
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Sep 10, 2026 ยท NCT07210515

High Potency Cannabis: Acute and Protracted Effects

  • UCLA Center for Cannabis and Cannabinoids, Los Angeles
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 55 ยท All sexes ยท Updated Sep 4, 2026 ยท NCT06859723

Effect of Magnesium on Neuromonitoring

  • University of California San Francisco Hospital, San Francisco
RecruitingPhase 4
Ages 18 and older ยท All sexes ยท Updated Aug 21, 2026 ยท NCT06975072

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

  • Lucile Packard Children's Hospital, Palo Alto
RecruitingObservational studyHealthy volunteers welcome
Ages 0 to 20 ยท All sexes ยท Updated Aug 21, 2026 ยท NCT04278404

Aromatherapy and Its Impact on Preoperative Anxiety, Postoperative Pain, and Patient Experience

  • Kaiser Permanente Stockton Ambulatory Surgery Unit, Stockton
RecruitingHealthy volunteers welcome
Ages 18 and older ยท All sexes ยท Updated Aug 18, 2026 ยท NCT07771205

Anesthetics and Analgesics in Children

  • Lucile Packard Children's Hospital, Stanford
RecruitingObservational study
Ages 0 to 17 ยท All sexes ยท Updated Aug 5, 2026 ยท NCT03427736

Randomized Controlled Trial of the STEIN Protocol: A Neuroplastic Pain Education and Guided Breathing Intervention During Awake Cataract Surgery

  • Stein Eye Institute - University of California Los Angeles, Los Angeles
Recruiting
All ages ยท All sexes ยท Updated Jul 23, 2026 ยท NCT07715591

Biofield Therapy for the Support of Immunotherapy-related Symptoms Among Adult Cancer Patients - A Pilot Study

  • UCI Health Susan Samueli Integrative Health Institute, Irvine
  • UCI Health, Orange
Recruiting
Ages 18 and older ยท All sexes ยท Updated Jul 10, 2026 ยท NCT07581080

Regional Blocks for Lateral Condyle Fractures

  • Orthopaedic Institute for Children, Los Angeles
RecruitingPhase 4Healthy volunteers welcome
Ages 4 to 12 ยท All sexes ยท Updated May 5, 2026 ยท NCT03796572

Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response

  • VA Loma Linda Healthcare System, Loma Linda, CA, Loma Linda
  • VA Long Beach Healthcare System, Long Beach, CA, Long Beach
  • VA Palo Alto Health Care System, Palo Alto, CA, Palo Alto
Recruiting
Ages 18 and older ยท All sexes ยท Updated May 4, 2026 ยท NCT04142177

A Randomized Controlled Trial of a Nutritional Intervention for Endometriosis

  • UCSD Health, La Jolla
Recruiting
Ages 18 to 45 ยท Women ยท Updated Apr 28, 2026 ยท NCT07090096

Clinical Trial Exploring the Outpatient Treatment of Phantom Limb Pain With Ketamine Administration in a Six Month Study With a Minimum Remission Period of 7 Days Between Treatment Session. 25-30 Subjects With an Ongoing History of Significant PLP.--FDA and IRB Approved.

  • Shamynds, Sacramento
  • Ketamine Research Foundation, San Anselmo
  • Mystic Health, Santa Monica
RecruitingPhase 2/3
Ages 18 to 65 ยท All sexes ยท Updated Mar 18, 2026 ยท NCT07276542

Virtual Reality (VR) for Interventional Radiology (IR) Procedures

  • Children's Hospital Los Angeles, Los Angeles
RecruitingObservational study
Ages 8 and older ยท All sexes ยท Updated Mar 9, 2026 ยท NCT07427862

Prehospital Analgesia INtervention Trial (PAIN)

  • University of California, San Diego, San Diego
  • Zuckerberg San Francisco General Hospital, San Francisco
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Mar 9, 2026 ยท NCT05437575

Phase 1 Study of SBS-147 in Healthy Adults

  • AltaSciences, Inc, Cypress
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 55 ยท All sexes ยท Updated Mar 3, 2026 ยท NCT07335913

The Effect of Intraoral Transcutaneous Electrical Nerve Stimulation in Orthodontics Pain

  • University of the Pacific, Arthur A. Dugoni School of Dentistry, San Francisco
RecruitingHealthy volunteers welcome
Ages 12 and older ยท All sexes ยท Updated Feb 17, 2026 ยท NCT06573996

Virtual Reality vs. Music Relaxation for Reducing Anxiety and Pain During Breast Biopsies

  • Westwood, Los Angeles
Recruiting
Ages 18 and older ยท Women ยท Updated Feb 5, 2026 ยท NCT07310004

Optimizing Chronic Pain Care With Mindfulness and Chronic Pain Management Visits

  • UCSD Health, La Jolla
RecruitingPhase 3
Ages 18 and older ยท All sexes ยท Updated Feb 3, 2026 ยท NCT06387290

Defense and Veterans Center for Integrative Pain Management (DVCIPM) Pain Registry Biobank

  • Naval Medical Center San Diego, San Diego
RecruitingObservational studyHealthy volunteers welcome
Ages 18 to 80 ยท All sexes ยท Updated Jan 28, 2026 ยท NCT04004286

Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain

  • UCLA Mattel Children's Hospital Ronald Reagan Hospital, Los Angeles
Recruiting
Ages 16 to 30 ยท All sexes ยท Updated Jan 7, 2026 ยท NCT06374238

Age-dependent Effects of Smoked and Oral Delta-9-THC

  • UCLA Center for Cannabis and Cannabinoids, Los Angeles
RecruitingPhase 1Healthy volunteers welcome
Ages 18 to 65 ยท All sexes ยท Updated Jan 7, 2026 ยท NCT05865470

DoD AtMS for Posttraumatic Peripheral Neuropathic Pain

  • Veterans Medical Center - San Diego, San Diego
Recruiting
Ages 18 and older ยท All sexes ยท Updated Dec 24, 2025 ยท NCT07301177

THC and CBD: A Controlled Human Study Probing a Harm Reduction Strategy

  • UCLA Center for Cannabis and Cannabinoids, Los Angeles
RecruitingPhase 1Healthy volunteers welcome
Ages 21 to 55 ยท All sexes ยท Updated Dec 17, 2025 ยท NCT06859710

VR AI Meditation for Pain

  • Cedars-Sinai Medical Center, Los Angeles
Recruiting
Ages 18 and older ยท All sexes ยท Updated Nov 26, 2025 ยท NCT07122843

Comparison of Transforming Powder Dressing to NPIAP Recommended Standard of Care Therapies in Stage 2, 3 and 4 Pressure Injuries

  • San Diego VA, San Diego
RecruitingHealthy volunteers welcome
Ages 18 to 85 ยท All sexes ยท Updated Nov 20, 2025 ยท NCT05496296

Perfusion MRI-targeted Joint Embolization for Chronic Musculoskeletal Pain of the Shoulder, Hip and Knee

  • VA Palo Alto Healthcare System, Palo Alto
RecruitingObservational study
Ages 25 to 80 ยท All sexes ยท Updated Aug 7, 2025 ยท NCT05700682

Freedom-1 Study for Chronic Knee Pain

  • Western Clinical Research, Placentia
Recruiting
Ages 18 and older ยท All sexes ยท Updated Feb 13, 2025 ยท NCT03877653

The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome

  • Altman Clinical and Translational Research Institute, La Jolla
  • University of California, San Diego, San Diego
RecruitingPhase 1
Ages 21 to 75 ยท All sexes ยท Updated Jun 7, 2024 ยท NCT06393101

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.