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Scleroderma clinical trials in Houston, TX

9 studies for Scleroderma are looking for participants at sites in and around Houston (within about 30 miles). Open a study to see who can join and how to contact the study team.

Testing an Immunotherapy Anti-cancer Drug, Nivolumab, for Advanced Cancers in Patients With Autoimmune Disorders, AIM-NIVO

RecruitingPhase 1
  • UT MD Anderson Cancer Center, Houston
Ages 18 and older · All sexes · Updated Sep 23, 2026 · NCT03816345

A Study to Test Whether Nerandomilast Helps People With Systemic Sclerosis

RecruitingPhase 3
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Sep 17, 2026 · NCT07497087

Platform Clinical Study for Conquering Scleroderma

RecruitingPhase 2
  • University of Texas Houston - Division of Rheumatology and Clinical Immunogenetics, Houston
Ages 18 and older · All sexes · Updated Aug 18, 2026 · NCT06195072

A Phase 1/2 Study of NKX019 in Subjects With Immune-Mediated Diseases (Ntrust-2)

RecruitingPhase 1/2
  • Nkarta Investigational Site, Houston
Ages 18 to 75 · All sexes · Updated Aug 7, 2026 · NCT06733935

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

RecruitingPhase 2
  • Artiva Investigational Site Bellaire, Bellaire · 7 mi away
Ages 18 and older · All sexes · Updated Jul 31, 2026 · NCT06991114

A Study of Microbiome Transplantation for the Treatment of Constipation and/or Significant Bloating in Patients With Systemic Sclerosis

RecruitingPhase 2
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Jul 8, 2026 · NCT06827977

Phase I/II Study of AD-PluReceptor Plus Tafasitamab-cxix and Lymphodepleting Chemotherapy in Patients With Autoimmune Disorders

RecruitingPhase 1/2
  • MD Anderson Cancer Center, Houston
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Apr 15, 2026 · NCT06434363

Interrogating the Pathophysiological Mechanisms of Constipation in Patients With Systemic Sclerosis

Recruiting
  • The University of Texas Health Science Center at Houston, Houston
Ages 18 and older · All sexes · Updated Jun 26, 2025 · NCT05989763

Study to Evaluate the Efficacy, Safety, and Tolerability of Efzofitimod in Patients With Systemic Sclerosis (SSc)-Related Interstitial Lung Disease (ILD) (SSc-ILD)

RecruitingPhase 2
  • aTyr Investigative Site, Houston
Ages 18 and older · All sexes · Updated May 7, 2025 · NCT05892614

About Scleroderma

Scleroderma is an autoimmune disease that causes inflammation and thickening in the skin and other areas of the body. The exact cause of scleroderma is unknown.

More about Scleroderma on MedlinePlus

Scleroderma trials in other cities

Other studies in Houston

From ClinicalTrials.gov, data retrieved Sep 30, 2026. Each study sets its own eligibility; the study team decides who can join.